What treatments have helped or not for generalize granuloma annulare?

Posted by bmh @bmh, Jul 9, 2024

I have tried 3 different topical creams, no help. Triamincilone, chlobesol, bethamethasone. Kenalog injections do work but they will not inject me anymore as I have too many. I tried otezla, after 2 months, just more lesions and I couldn't take the side effects anymore. Now I am going to try a jak inhibitor called opzelura cream. I'll test that for 2-3 months. If that doesn't help ill try Hydroxychloroquine pills. Most don't bother me, some itch. I just keep getting more, probably close to 100 and growing more. Anyone have had any success or fails?

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Originally I was prescribed
Clobetasol propionate 0.05% cream and used for 3 months. Not effective at all. And increased /red and elevated rim around patches.
Now using Tofacitinib ointment 2X/ day for 6 months. Positive, slow results. New spots arise but with immediate application they don't spread. Redness has paled. I do have "scars" from older lesions and not sure if they'll disappear.

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