What antihistamines are okay to take with blood thinners?

Hi @zeke2u Members in Connect aren’t able to prescribe medications and your situation is unique to you so what works for some members may not be the right choice for you. Considering you take blood thinners, and possibly other medications, it’s really best if you check with your doctor or pharmacist to see what antihistamine would be safe for you to use.
Do you suffer from seasonal allergies?

I haven't gone to look for an answer, although the previous response is bang-on...for a first orientation. But, at first glance, the antihistamine is more likely to cause an 'arousal' response to the heart as caffeine would. It should have no impact on an unrelated medication that is used to retard the onset of clotting.

Note that we use the term 'blood thinners' indiscriminately and often incorrectly. If you are on a DOAC (Direct Oral Anti-Coagulant) such as rivaroxaban or apixaban, almost certainly there is no contraindication...but I will check for you. I can't say about warfarin because I have never taken it, nor been prescribed it.

Stand-by...

[less than a minute later...] https://www.webmd.com/interaction-checker/default.htm

So, as I suspected, no problem WITH DOACs. There could be problems with statins, cold medication/decongestants, WARFARIN. etc....so read the entire article, please.

And as suggested previously, always give your primary care giver/GP the chance to advise you when you seek a self-remedy of ANY KIND.

I am on a DOAC - Xarelto - for Factor 5 clotting and it has worked well for me with one huge exception. I had an eye surgery in 2018 to insert a drainage tube for glaucoma. Two hematologists told me to stop the Xarelto for two days beforehand, but I stopped it for four days just out of caution. There was a bleed at the surgery and then about a month later, the day of my post-surgical checkup, everything went black and there was a huge pain in my head. I thought I was having a stroke and went to my appt. By that time a little vision had returned. I was reassured that everything still looked okay, looked good in fact, but before I left the building it all turned black again. My eye wall had collapsed from a huge bleed.
Two surgeries to drain blood followed and I kept being assured that the blood would reabsorb or be drained but that didn't happen. My hematologist explained that Factor V makes a very tough clot.
A retina specialist explained to me that all these - I think he called them neo-nics - drugs are very problematic for surgery, because the veins in the eye are tiny and weak. He said you need to be off them for ten days before surgery even if you don't have a genetic clotting disorder. When I asked him how he knew this, he said retina specialists work with a lot of older eye patients who need eye surgery and he had seen this happen before. I saw him for a couple of years and although there was a teeny improvement, basically I lost that eye. You don't want to be 80 years old and lose an eye; six years later I still have mixed dominance, no depth perception, and am quite off balance in general.
If you're on these drugs and need eye surgery, ask a LOT of questions.