Weight Gain with Evenity

Posted by susanew @susanew, Feb 11, 2025

Some have said they gained some weight when taking Evenity. Any idea at about what shots you noticed this? I am now going to be taking shots #9 and I do notice about a 4 to 5 lb. gain. Anyone else notice a gain in weight and if so, when was it noticeable?

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Profile picture for ojaimama @ojaimama

I noticed it immediately, withinn the first 1-2 weeks. It was gradual through the 12 shots. 8-9 lbs gained after 12 shots with exercising more and eating less. It's now late Jan 2026 .Last shot was late Aug 2025. STILL eating less (than before Evenity) and exercising more and the weight will not come off. Evenity changed my metabolism for sure and I am so frustrated.

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That is exactly what happened to me while receiving the Evenity injections!
Everything about me changed!
So disappointed!

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I have just finished my 12 month treatment. I have gained 15 pounds since I began. I have even reduced caloric intake, to no avail.

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I am getting my 4th Evenity injection next week for spine surgery in Sept. I have noticed ankle & foot edema & trouble with weight. Is this something anyone else has experienced?

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Did you notice any ankle & foot edema? I am struggling with this

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I have edema in my feet & ankles. Anyone else have this? So frustrating

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I'm coming up on my 8th injection and no, I haven't had any weight gain. I've had no side effects other than the usual soreness at the injection site.

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I just got my fifth round of shots, and I noticed that I am gaining about a half a pound a month without dietary changes. And I doubt that it’s all bone mass. Hope this effect goes away when treatment is complete.

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Profile picture for sunbeam10 @sunbeam10

I just got my fifth round of shots, and I noticed that I am gaining about a half a pound a month without dietary changes. And I doubt that it’s all bone mass. Hope this effect goes away when treatment is complete.

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@sunbeam10 Anecdotal but I gained eight pounds over my treatment and it's all gone now. My last dose was at the beginning of April.

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Profile picture for oopsiedaisy @oopsiedaisy

@sunbeam10 Anecdotal but I gained eight pounds over my treatment and it's all gone now. My last dose was at the beginning of April.

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@oopsiedaisy: I’m Jealous! If you don’t mind my asking…was your added “fullness” mostly in midriff? My weight has stayed the same, but after 12 months Evenity I have added a little roll around my middle (all my shots were in my stomach).
Please share your actions to make your results back to “ normal” since April! I await your reply! Thanks for your help!

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Profile picture for dbamos1945 @dbamos1945

@oopsiedaisy: I’m Jealous! If you don’t mind my asking…was your added “fullness” mostly in midriff? My weight has stayed the same, but after 12 months Evenity I have added a little roll around my middle (all my shots were in my stomach).
Please share your actions to make your results back to “ normal” since April! I await your reply! Thanks for your help!

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@dbamos1945 Yes, it was the dreaded muffin top/stomach roll. Not that I don't still have some extra pudge around my middle which came on with menopause, even though I exercise and watch my diet.

I do think some of it was water retention as well.

I haven't made any changes since I stopped Evenity. My exercise routine and diet have remained the same for the past few years.

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