Weaning off Metoprolol

Posted by kenny48 @kenny48, May 11, 2018

Hi,
I've been taking both flecainide and metoprolol now for eight years, as a prophylactic for Afib. I recently moved to North Carolina and have a new Cardiologist. Have had a lot of PVC's this past two months, and had to wear a heart monitor for an entire month. He said that although I had a lot of PVC's I didn't have even one PAC! He also noted that my BPM was low in the low fifties most of the time. He asked why I was taking metropolol. I told him that the only thing my previous doctor had said was " it makes the flecainide, work better". He suggested I stop taking the metoprolol to see how I do without it. Unfortunately I read a lot of information on the internet. I read that it can be very dangerous to stop taking it. I take 25 mg metoprolol succinate, split in half. Once in the morning with my flecainide, and then again in the evening for a second dose. He wants me to take half in the morning and skip the evening dose for two days, then stop entirely. Has anyone else stopped taking this drug in a similar manner? I'm worried that the cut off is too soon.

Liked by healthytoday

I also was on metoprolol 25mg and flecainide 100 mg each. Managed a total of 1 month and felt so awful that I was taken off. Weaned off over 5 days with no issues.

Liked by joma7862

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I was on 25mg twice a day. While on it, I gained weight and could not get it off. I got out of breath easily. I told my doctor about it and he scheduled a nuclear stress test. The stress test found no problems except leaving my bank account a grand lighter. Not the kind of weight loss I was looking for. So, I quit taking Metropolol cold turkey a week ago. I had no issues. Maybe because I was on a smaller dose. Already, taking three flights of stairs does not leave me winded. I'm bothered by the fact my doctor discounted the side effects. Now to get the weight off.

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I'm very surprised at these reports. I've been taking Metoprolol for several years now And I also take eliquis, and that's all I take. It's been evaluated several times, and my A-fib is said to be under control. Yes, I have certainly aged, but am not suffering from your symptoms. I'm surprised to see that long list. I am new to this list, so hi everybody.

Liked by Soliloquized

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It depends on your medical condition. I'm on Toprol XL for high blood pressure, but also have hypothroidism that is resulting in a very low heart beat. I'm not happy that I trusted my doctor and she put me on this drug that I can't get off without life threatening side effects.

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I am on metoprolol 100mg and I am experiencing side effects. I plan to call my cardiologist off today to tell them about the side effects. I have a irregular heart beat too fast but this morning I woke up to the worse dizziness I have ever had and looking at the side effects it's making the fluttering worse not better. If you been taking 100mg how long does it take to break down in your system for some of side effects to be less. Kim

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@anxious60

I am on metoprolol 100mg and I am experiencing side effects. I plan to call my cardiologist off today to tell them about the side effects. I have a irregular heart beat too fast but this morning I woke up to the worse dizziness I have ever had and looking at the side effects it's making the fluttering worse not better. If you been taking 100mg how long does it take to break down in your system for some of side effects to be less. Kim

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Metoprolol Tartrate:
The mean elimination half-life of metoprolol is 3 to 4 hours; in poor CYP2D6 metabolizers the half-life may be 7 to 9 hours.

Metroprolol Succinate:
Elimination is mainly by biotransformation in the liver, and the plasma half-life ranges from approximately 3 to 7 hours. 

This drug has a short half-life. Though not related, Xanax averages 11.2 hours, Klonopin 35 hours, and Valium 100 hours, once they have reached a steady state. I give this example to show how short the half-life of Metroprolol is.

I wouldn't do anything without your cardiologist's knowledge and hopefully approval, or approval of another doctor familiar with your health and conditions, like that which may happen to those seeking Emergency Room Treatment.

I'd think that within 48 hours, the Metroprolol would be out of your system, for all intents and purposes.

I'm taking 200 mg Metoprolol Succinate in the morning, 25 mg Metoprolol Tartrate mid-afternoon, and 150 mg Metoprolol Succinate at night. My cardiologist prescribed 200 mg Metoprolol Succinate in the morning and 200 mg Metoprolol Succinate in the evening, but my family doctor is aware how I'm taking it and did not object. Prior to my afib I was taking Acebutolol 200 mg three times a day, it's another Beta-Blocker, I no longer take that, but it seems I'm fairly tolerant of significant doses of, at different times of course, different Beta-Blockers.

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@joma7862

I would like to know how to reduce Toprol XL from 25 mg to 1/2 of the tablet. Toprol XL is reducing my heart beat to the low 50's and one day it was 48. I also take Losartan Potassium that my doctor increased to 50 mg a day, but can go up to 100 mg a day if needed. Even taking 1/2 tablet of Toprol XL speeds up my heart and increases my blood pressure even when I take other blood pressure pills. I feel trapped by this drug.

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@joma7862 I, too, am trying to wean off Toprol XL. I have been taking 12.5 mg for at least 13 years. Today is the first day where I halved the 12.5 and my blood pressure is rising. My doctor wants me to do this for two weeks then stop. I am thinking this medicine has caused my hair to thin a lot. I am also on Cozaar which has had several voluntary recalls due to a carcinogen contamination. I'm not sure what I am going to switch to. After all, most generic forms are manufactured overseas where there's no safety regulations enforced.

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@oldertoo

@joma7862 I, too, am trying to wean off Toprol XL. I have been taking 12.5 mg for at least 13 years. Today is the first day where I halved the 12.5 and my blood pressure is rising. My doctor wants me to do this for two weeks then stop. I am thinking this medicine has caused my hair to thin a lot. I am also on Cozaar which has had several voluntary recalls due to a carcinogen contamination. I'm not sure what I am going to switch to. After all, most generic forms are manufactured overseas where there's no safety regulations enforced.

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Let me know if this works. I have not cut down to 12.5mg due to rising blood pressure when I try.

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is memory loss regained when metoprolol is stopped

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@jonpat

is memory loss regained when metoprolol is stopped

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I would like to know about memory loss too and if everyone has brain fog taking Metoprolol.

Liked by Soliloquized

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Welcome to Connect, @katydid77,

I found a few published studies the effects (positive and negative) of cardiovascular medicine on the brain, which you might like to read:
– Neuropsychiatric consequences of cardiovascular medications https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181843/
– Beta-blockers: Acting in the Brain But Healing the Heart https://www.medscape.com/viewarticle/578687

While we wait for other members to return with their insights, could you share a bit more about yourself? Have you been taking Metoprolol for a long time?

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@katydid77

I would like to know about memory loss too and if everyone has brain fog taking Metoprolol.

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Oh heck no. I'm on nearly 400 mg of Metoprolol Succinate in divided doses, and 500 mg of Dilantin in divided doses, and taking Ranitidine (Zantac), Singulair, and Xyzal (all three of those for Chronic Urticaria) and Zocor for Cholesterol, according to literature, I should be a babbling sleepwalker, but honestly, I feel fine.

Results vary between individuals, in no way, shape, or form am I insinuating that certain people aren't experiencing brain fog even with lower doses, we all react differently to medications, I just wanted to assure you Brain Fog isn't necessarily a result.

One caveat. Dilantin can depress Vitamin D levels, and lack of sunlight in the winter the same, and at one time I'd get Seasonal Affective Disorder (SAD) so on my own, I started taking 2000 IU of Vitamin D3 once a day, 365 days of the year, and it made a HUGE difference in my Seasonal Depression, I'm not sure if it helps with cognition too. Always consult with your doctor or pharmacist before adding supplements, either vitamin or minerals.

Here's just one of the interactions possible between Vitamin D3 and one of the prescriptions I take, but my doctors are aware that I take it and the Neurologist tested me to be sure I was taking enough, which I am. Plus I'm not taking a High Dose of vitamin D3:

""MONITOR: Coadministration of thiazide diuretics with high dosages of calcium and/or vitamin D has been associated with reports of hypercalcemia in some patients. Thiazide diuretics inhibit the renal excretion of calcium and may also enhance responsiveness of bone and renal tubule to parathyroid hormone, thus concurrent use of large amounts of calcium or vitamin D can lead to excessively high plasma levels of calcium. Patients who are particularly susceptible include those with hyperparathyroidism, those being treated for osteoporosis, and those receiving high dosages of vitamin D for hypoparathyroidism. Metabolic alkalosis and the milk-alkali syndrome have been reported during prolonged therapy with thiazide diuretics and calcium.""

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@joma7862

Let me know if this works. I have not cut down to 12.5mg due to rising blood pressure when I try.

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I've been on metoprolol about 8 months for one bout of afib. I was prescribed 25mg twice daily. I took that for 2 days and my pulse was in the 40s so went down to once a day. It was still low 50s so I went to 12.5 and have been on that for most of the time. My resting pulse is mid 60s which is lower than it's been my whole life. I'm sensitive to most drugs and metoprolol I think is one of them. I'm having terrible back and hip pain to the point of it affecting how I walk. I've told my cardiologist and my pcp but they both say metoprolol isn't the cause especially at such a low dose. Tonight I started halving the 12.5 and will use that for a week and then stop. If after a few weeks if the pain goes away I'll know it was the drug and see what alternative drug is suggested by my cardiologist. Has anyone else had back and hip pain?

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Are you taking statins also? Statins can cause muscle pain and loss. If you are, there is a recommendation to take CoQ10 supplements as well.
I take both statins and metoprolol tartrate, also at 12.5 mg twice per day. I doubt my pains are due to the latter, but I've never tried eliminating them. I also cut mine to half dose because of the effect it had on my heartbeat.

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@jackj

Are you taking statins also? Statins can cause muscle pain and loss. If you are, there is a recommendation to take CoQ10 supplements as well.
I take both statins and metoprolol tartrate, also at 12.5 mg twice per day. I doubt my pains are due to the latter, but I've never tried eliminating them. I also cut mine to half dose because of the effect it had on my heartbeat.

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All I take is metoprolol and vitamin d3.

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