WBC count keeps getting lower and lower

I would not speculate very much as to why your WBC is dropping. Of course it is a common thing to see WBC drop for a person dealing with any of a number of diseases or treatments for those diseases. However, from reading your query it doesn't sound like you are aware of any thing. What was the occasion that you received a Blood Count test in the first place? If you are not seeing an Oncologist then I would suggest that you do so rather quickly. If you are indeed seeing one and he/she doesn't see any reason for the drop, then I suggest that you get a second opinion. Much better to find the cause sooner rather than later. Best of luck to you.

Thank you for your reply.
I have osteoporosis and that in and on itself requires me to receive a blood count and other lab tests pretty often. And I would do a blood count every 2-3 months regardless as a part of a basic health and wellness check.

I'm not seeing an oncologist or hematologist because I haven't had a reason for that until now.
I'm not going to lie, but your comment scared me a little bit 🙁

Best regards

My WBC has been low for years, near or below normal range. I asked my oncologist if that compromised my immune system, and he said "no" my other blood work was normal range. I'm 69 and have a few autoimmune diseases, no cancer (just MGUS), and am otherwise healthy and very active. It would be good to check with your doctor on this and get an evaluation of all of your test results.

Thank you for reply.

I've heard about the fact that some people have naturally lower levels of WBC that don't signal any health issue. The thing that worries me is that my counts keep getting lower and lower over time.
I will discuss it with my doctor for sure, as soon as possible

Best regards

You should seek the expertise of a Hemotologist. None of us here are doctors. From my experience it is not good to worry. You need to know what is going on, then you can deal with your diagnosis.

Thank you for your reply!
The motivation for my post was not to seek a diagnosis, I'm fully aware that it cannot happen... But rather, I wanted to read some similar experiences.

Sophie: Understand, but most the people here have serious issues. I noticed you replied on one post that it made you fearful because your symptoms are similar to that responder. I do not want you to be fearful or worry because those emotions are not helpful. I ended up in some rabbit holes when I was waiting for confirmation of my diagnosis. I could have spent the energy much better at the time.

I had the same thing happen to me. I was being dismissed until I pointed out that my WBC count had been dropping steadily over a year’s span. I was then referred to a hematologist who performed a bone marrow biopsy with Next-Generation Sequencing (NGS).. It was determined that I have clonal cytopenias of undetermined significance (CCUS) with a low level mutation in the KMT2C gene. My hematologist wants to see me every 6 months, and I’m in a watch and wait scenario. It could turn into something down the road. My main goal is to reduce the inflammation in my body by exercise and eating better. My WBC has never gotten as low as your 2.1, so I think a referral to a hematologist is the right direction for you. Also, besides my absolute neutrophils, glucose, A1C, and cholesterol, my other bloodwork looks fine.

Per my hematologist, “ This condition may never develop into a blood disease but does increase the risk of a pulmonary disease known as myelodysplastic syndrome. Therefore, it should be monitored periodically to ensure there is no progression of the low white blood cell count and/or the development of additional abnormalities.”

More info on CCUS:
https://blog.dana-farber.org/insight/2019/04/what-is-clonal-cytopenia-of-undetermined-significance-ccus/

Thank you for your reply.
I have an appointment booked soon, so my WBC will be tested once again and we will see from there. My doctor mentioned that maybe this low WBC count is a consequence of some past infection, but then again, the drop has been pretty steady over the course of months, which is the thing that worries the most.

I will try not to panic and just follow my doctor's advice

Best wishes to you!

Definitely get to a hematologist and a bone marrow biopsy will give you a lot of answers. At least give you some ideas of what your body is doing.