Was there an uptick in autoimmune conditions after COVID vaccines?
A few years ago I experienced intense vaginal itching. I tried various over the counter creams, none of which helped. In desperation I went to a walk-in clinic (I was unable to get in to my primary care doctor) and I was examined by a Medical Assistant who prescribed a steroid cream. She said that there was a stronger one that she hesitated to prescribe because it can cause thinning of the skin. The cream was not successful and eventually I was able to see my PCP who said this was Lichen Planus and prescribed Betamethasone cream. That, thankfully was effective. The following year when I had my yearly health check I complained that my legs were very itchy. My PCP looked at them and said that I could try an OTC steroid cream. This was shortly after I had a COVID booster. I then made an appointment with my dermatologist and asked if he thought I was having a reaction to a new medication that I was taking for blood pressure. He said "this isn't a drug reaction, I think this is Lichen Planus!" He prescribed Betamethasone and it was effective although I still get occasional red, itchy bumps. I have learned (from Mayo Clinic Connect) that this is an autoimmune condition and wonder now if an uptick in autoimmune conditions has been seen since the administration of COVID vaccines.
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Note from the Community Director
The vaccines that help protect against COVID-19 are safe and effective. Clinical trials tested the vaccines to make sure of those facts. Healthcare professionals, researchers and health agencies continue to watch for rare side effects, even after hundreds of millions of doses have been given in the United States.
Side effects that don't go away after a few days are thought of as long term. Vaccines rarely cause any long-term side effects.
If you're concerned about side effects, safety data on COVID-19 vaccines is reported to a national program called the Vaccine Adverse Event Reporting System in the U.S. This data is available to the public. The U.S. Centers for Disease Control and Protection (CDC) also has created v-safe, a smartphone-based tool that allows users to report COVID-19 vaccine side effects.
If you have other questions or concerns about your symptoms, talk to your healthcare professional.
From Mayo Clinic: COVID-19 vaccines: Get the facts
Interested in more discussions like this? Go to the Autoimmune Diseases Support Group.
Connect

Hi All,
One year post COVID vaccine I also developed multiple autoimmune problems. I had a reaction 5 min post vaccine injection with high blood pressure >200 and malaise. They took me to ER - it got resolved in 4 hrs. But 1 year later I developed purple fingers with Raynaud, scleroderma or systemic sclerosis with skin discolorations and thickening, restrictive lung disease, and joint stiffness and inflammatory arthritis. Multiple unexplained food and drug allergies as well.
Please share you experience in a greater detail. What is your current diagnosis? Did you test positive for ANA and SCL-70 tests?
@altabiznet Cellcept and IVIG infusions.
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1 Reaction@admeliora, I'm so sorry you are suffering. And you are right the research isn't reflecting the connections. Even the last big study out of Korea does not indicate that many of the conditions suffered by people who actually had Covid 19 are being experienced by those who had the vaccine.
I consider that most of our medications are not adequately researched before the rush to market. But this rush to market wasn't profit driven. It was a pandemic that killed seven million people. Most of us made the choice not to risk dying after weeks or months of abject misery.
It is known in medical science that our bodies are manipulating the immune system with an inactive virus in the same ways that the active virus activates the immune system.
I had the vaccine the day it became available to me and have had every boost since. I'm grateful that Moderna began studying the vaccine early, before it became evident exactly how miserably deadly the covid vaccine would become.
It's hard to know if you are better off with the side effects; you may never have contracted Covid. My neighbors refused the vaccine; they and all four of their children suffered the virus; two of the children have long Covid.
Rest assured, though there won't be a vaccine for the next pandemic. We won't have to make a choice.
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2 Reactions@philipnewbury
Any improvements?
What is your dose level of Cellcept and for how long you have been taking it? Also, how many IVIG infusions before you see improvement?
Many thanks for sharing.
@gently
Thank you for your concern. I had Moderna when it came out too. My immune system went nuts. I don’t feel this is a forum to discuss it except to say the mRNA factor was a key to alot of this mess. PEG was in alot of allergy meds pre-Covid for decades. When the vaccine was produced, what they decided to do with it in the vaccine is a very serious matter. The result for me is my allergy list doubled from 45 lifetime pre-vaccine (already high) to 102 in less than 4 years. Others have exponential allergies to meds in comparison also as a result. I am told my immune system is now fighting my body. I’ll say it is! I’m going to leave it at that. The question I have now is I was not an anti-vaxer. What would I do now if I need any other vaccine? I can’t have a single one anymore. But if I could, I wouldn’t. That doesn’t make me an anti-vaxxer. I really question what they did with that one, why, and what will happen with any new vaccines as a result of the liberty they took.
@admeliora
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2 ReactionsAdmeliora, I respect your privacy and thank you for telling what you can in this forum. Was PEG a known prior allergen for you.
Were you aware of cause soon enough to file a CICP, or were you even made aware of the program.
The hrsa data base probably barely reflects the extent of the problem.
This https://www.med.unc.edu/neurology/car-t-cell-therapy-autoimmune-disease-treatment/ might be too scary to even contemplate I hope something changes and you can recover from these last long years.
@pm56
I'm totally in agreement with you on the covid trigger, not as much on the vaccine trigger, but I know there are two words in the English language that are overused and seldom true... never and always.
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1 Reaction@pm56
Interesting reading about your history. I had just been reading about my newly diagnosed RA and symptoms. I had just been wondering if when I had COVID 3+ years ago if that triggered my symptoms. My Rheumatologist when he first saw me said that my symptoms looked like they had been around for about 3 years. I never took the vaccine (and will never) as seeing all the serious side effects like blood clots.
This is all very eye opening from reading what might be the triggers to auto immune diseases.
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4 Reactions@gently
I for one, didn't take the vaccine (won't ever) did get a mild COVID about 3 years ago and recently diagnosed with RA.
Interesting!
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1 Reaction@betsyhase could very well be. In many cases I don’t think we’ll ever know for sure, but that is my rheumatologist’s own personal view and I’m inclined to believe her. I’ve never been sicker than I have been since I got Covid.
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3 Reactions