Since 2001 I have slowly been gaining weight. In May of 2001 I weighed about 140 now I am pushing 310. The last year I put on 50 lbs alone and now my doctor is staring to see there are issues. I do have PCOS, IBS, Diabetes, and Asthma and they are very cautious to add me on meds that might harm my liver (I am in the beginning stages of liver disease). So far we have ruled out issues with my heart and the only thing they can find wrong in my lungs is the asthma. Has anyone ever experienced anything like this? I have tired and tried to lose weight and all I seem to do is gain weight. For one week I did weigh my daily and I would lose/gain anywhere form 5 to 10 lbs. Im lost and getting really aggravted at this. The other issue is I have extreme swelling in my hands and feel. They put me on HCT and took me off the Lasix but the only way to keep them down is to take both of them together (even at the risk of kidney damage). Is there anything i can suggest to my dr to test for? Also I have started having issues with my bladder and dont empty it nearly enough or at all.