I have been tolerating the Big 3 for almost a year. I have had negative AFB sputum cultures since March. Over the last few weeks, I started experiencing nausea. It was intermittent at first , but now it’s daily. I’ve tried peppermints, ginger ale, even Zofran, without relief. I don’t have any history of reflux/GERD, but have tried taking Omeprozole without success. I take the antibiotics M-W-F and have tried spreading them out over the course of the day, taking all with food now, but to no avail. Has anyone experienced nausea so late in the treatment? Any suggestions for nausea control would be greatly appreciated!