Trial for new epilepsy med

Posted by cathy5161 @cathy5161, May 18, 2025

Shortly starting an open label clinical trial to evaluate a new epilepsy drug called vormatrigine, developed by Praxis Precison Meds. It's 14 weeks long, divided into extensive screening, and a number of visits with a great deal of assessments and procedures. Belive this is first phase, which I'm sure with no placebo, looking for side effects and adverse reactions to study drug. 50 or so participants, across the globe, who have focal onset or tonic-clonic seizures, all getting same dosage, are the first guinea pigs.
1. Anyone heard of this trial or study drug?
2. Anyone actually doing it?
3. Any other thoughts or comments?

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Ignore last sentence.

Scary episode on vacation in late June. Rare mistake of taking all epilepsy at midnight, then again at 7 am. Didn't realize it until I started feeling really weird. Got off couch and was absolutely impossible to walk a straight line. Lasted 3 hours. Kept calling the 24 hour trial emergency line but no one answered (it was Sunday). Very disturbing and scary. I skipped Sunday night's meds.

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Hi @cathy5161
What you've been through sounds very scaring. If I understand correctly, this happened while you were still participating in the trial, correct?
I'm so happy to hear that you haven't experienced any withdrawal effects—that's truly a blessing. 🙏
I hope your appointment with your doctor next week goes well. Please keep me posted on how everything goes.
Chris

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