Transplant: Amoxicillin for dental appointment

Posted by hello1234 @hello1234, Nov 17, 2021

Hi all,
I have an 8am morning dentist appointment next week. The dentist would like me to take 2,000mg amoxicillin one hour before the appointment to prevent infection. Normally at 7am I take my Cellcept and Envarsus XR. What do you do in this instance? Has anyone taken amoxicillin with Cellcept and Envarsus XR? Do you take amoxicillin when you visit your dentist or go for a dental cleaning? Thanks everyone!!

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@hello1234

@contentandwell If you find any good solutions to the sciatica, please let me know! There are sciatica exercise videos posted on YouTube by several physical therapists. I would think your orthopedic doctor may be a good resource too. It seems that the sciatica nerve gets inflamed and then feels like "pins and needles". If I walk too much, I can get it sometimes. If I sit too much, I can sometimes get it…. It's very arbitrary for me.
Thanks for all the good info JK!! 😊

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@hello1234 There is a lot of good info on this site:
https://www.emedicinehealth.com/what_triggers_sciatica/article_em.htm
including this:
Triggers for sciatic nerve pain include:
"Sitting too much
Being overweight/obese
Wearing high heels or uncomfortable/uncushioned shoes
Wearing overly tight, form-fitting pants, shorts, or skirts
Carrying bulky items in a back pocket, such as wallets and phones"

I strongly suspect my current flare has to do with sitting too much. I've been trying to Christmas shop on the computer.
JK

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@contentandwell

@hello1234 There is a lot of good info on this site:
https://www.emedicinehealth.com/what_triggers_sciatica/article_em.htm
including this:
Triggers for sciatic nerve pain include:
"Sitting too much
Being overweight/obese
Wearing high heels or uncomfortable/uncushioned shoes
Wearing overly tight, form-fitting pants, shorts, or skirts
Carrying bulky items in a back pocket, such as wallets and phones"

I strongly suspect my current flare has to do with sitting too much. I've been trying to Christmas shop on the computer.
JK

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Thank you for the great info @contentandwell I think sitting too long at the computer may be my reason too…Holiday Shopping Season! 😊

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@hello1234

Good morning @athenalee 😊 Hey, did you say you were in the hospital for a month and a week?….Is that the normal amount of hospital time after a liver transplant?

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No. I had a severe reaction to prednisone. But they didn’t want to take me off it for at least a week. I had wicked hallucinations! I kept trying to run away as I thought the nurses had kidnapped me. Then, there were bugs on the walls. My dog came to visit. Weird.

And, then I had to stay longer as I wasn’t getting enough protein and they kept me on the feeding tube the whole time…plus, I left with it.

And, I had some infection issues and trouble with ascites which had to be drained off…yuck. Not a pretty site. Funny, I was roaming through my photos the other day and found one just before my transplant when I weighed in at 137 due to ascites (107 now!). Having never been pregnant, I had new found great admiration for pregnant woman. And, one of my favorite homecoming experiences was getting to wear my favorite shoes again!

How long were you in the hospital for your transplant? Any issues? How’d you cope with Covid during your pre-transplant and hospital stay?

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@athenalee

No. I had a severe reaction to prednisone. But they didn’t want to take me off it for at least a week. I had wicked hallucinations! I kept trying to run away as I thought the nurses had kidnapped me. Then, there were bugs on the walls. My dog came to visit. Weird.

And, then I had to stay longer as I wasn’t getting enough protein and they kept me on the feeding tube the whole time…plus, I left with it.

And, I had some infection issues and trouble with ascites which had to be drained off…yuck. Not a pretty site. Funny, I was roaming through my photos the other day and found one just before my transplant when I weighed in at 137 due to ascites (107 now!). Having never been pregnant, I had new found great admiration for pregnant woman. And, one of my favorite homecoming experiences was getting to wear my favorite shoes again!

How long were you in the hospital for your transplant? Any issues? How’d you cope with Covid during your pre-transplant and hospital stay?

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@athenalee I had no idea that you experienced such an ordeal post-transplant. Over a month in the hospital. (And on top of all of this, due to covid you had no visitors). After the month and a week was over, did you go home or did you need to live close to the hospital in nearby long term housing? I'm not sure how far you live from Boston?
My post kidney transplant experience was pretty textbook (I am very, very,
very grateful!). I had my surgery on Thursday and I was discharged on Sunday morning. They were talking about Saturday, but it became Sunday morning which was no problem. Then I stayed at long term housing (rental) in Jacksonville for one month to be close to Mayo for my regularly scheduled 6am lab work and afternoon doctor appointments. They took great care of me! Of course my Tac was adjusted regularly too. The great thing about Mayo's lab is they have the Tac number in a few hours and my nurse would call me with any adjustment. At my local lab in South Florida, they have the Tac results in 5 DAYS, not five HOURS! My local hospital sends the blood vial to Labcorp on Monday and I normally get the Tac result on Friday. (That's another wonderful thing about Mayo…their lab and testing centers are extraordinary.) All in all, it was a great experience and I happily left with my new kidney! My only concern now is my elevated LIVER enzymes that are probably caused by the immune suppression drugs. My fear is ultimately they may need to further adjust or reduce my meds, which can increase the likelihood of rejection. My kidney numbers are doing so well. I wish the same was happening with the liver. I am not sure if they can just keep the liver enzymes running high without ultimately damaging the organ. I assume they are always weighing the pros and cons, similar to your awful prednisone side effects. They decided to keep you on the drug in spite of the adverse reactions. I am not sure if the liver will be same thing or if they will be forced to make an adjustment since these meds are lifetime and may cause damage to the liver after time?
I am so happy that you are through that early experience and now back to long chilly walks and dancing in the kitchen!! 💃😊💃

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@hello1234

Good morning @leahdrose 😊 Is today the day you have your appointment with your UCLA transplant nephrologist? I am thinking of you and looking forward to hearing about your visit! Please remember to ask about the protocol biopsy schedule at UCLA. I am interested in comparing it to Mayo's protocol schedule since I am very apprehensive about so many biopsies too. I hate the idea of an even tiny possibility of upsetting my fabulous new kidney. I know you feel the same way. Good luck on your visit! ❤

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@hello1234 My apologies for not keeping in touch soon. I just got a part-time remote job, and it has been hectic.
They identified the rejection was elevated through the Prospera blood test. It is more comprehensive and detects early rejection which later shows up on the usual creatinine test. I was told it is fairly new and existed a couple of years ago. I did another test today. The creatinine is better from 1.12 last week to 1.04. I also did another Prospera test as recommended by my UCLA nephrologist. If it goes further up, then they will schedule biopsy. In looking at the five test results, they were all in upward pattern. Most likely, the test today is up too. Last week, they also took antigens test. It came out good as no antibodies were detected against the antigens. There's always good news and bad news. Like everyone else, I entrust our doctors recommend the best course of action to keep us on the right track.

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@leahdrose

@hello1234 My apologies for not keeping in touch soon. I just got a part-time remote job, and it has been hectic.
They identified the rejection was elevated through the Prospera blood test. It is more comprehensive and detects early rejection which later shows up on the usual creatinine test. I was told it is fairly new and existed a couple of years ago. I did another test today. The creatinine is better from 1.12 last week to 1.04. I also did another Prospera test as recommended by my UCLA nephrologist. If it goes further up, then they will schedule biopsy. In looking at the five test results, they were all in upward pattern. Most likely, the test today is up too. Last week, they also took antigens test. It came out good as no antibodies were detected against the antigens. There's always good news and bad news. Like everyone else, I entrust our doctors recommend the best course of action to keep us on the right track.

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Hi @leahdrose 😊 No need to apologize! I am so happy to hear from you!
It's nice to hear that you have a remote part time job that you are enjoying. With covid, a remote job is perfect and recovering from the kidney transplant makes the part time hours advantageous too!
It sounds like your appointment at UCLA went well. I know what you mean about a mixed bag of good test numbers and a few test numbers that need to be watched…..That's my experience too.
It's great to know about the blood test that monitors for signs of rejection! My doctor recently mentioned a test called "Allosure" which sounds very similar to the test you mentioned. (Maybe it's just a different brand or manufacturer).
It sounds like you will continue to monitor and the good news is nothing sounds urgent. I like the idea that you will only biopsy if the blood test shows it's needed.
I was also happy to hear that you have great confidence in your UCLA transplant doctors and team. They have an excellent reputation!
Please keep me posted on your results from today and whether things are calming down or you need the biopsy.
A lot of your blood work results sound really good so I am hoping that you will be pleasantly surprised.
Will you receive the results from today's blood work this week?

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@hello1234

@athenalee I had no idea that you experienced such an ordeal post-transplant. Over a month in the hospital. (And on top of all of this, due to covid you had no visitors). After the month and a week was over, did you go home or did you need to live close to the hospital in nearby long term housing? I'm not sure how far you live from Boston?
My post kidney transplant experience was pretty textbook (I am very, very,
very grateful!). I had my surgery on Thursday and I was discharged on Sunday morning. They were talking about Saturday, but it became Sunday morning which was no problem. Then I stayed at long term housing (rental) in Jacksonville for one month to be close to Mayo for my regularly scheduled 6am lab work and afternoon doctor appointments. They took great care of me! Of course my Tac was adjusted regularly too. The great thing about Mayo's lab is they have the Tac number in a few hours and my nurse would call me with any adjustment. At my local lab in South Florida, they have the Tac results in 5 DAYS, not five HOURS! My local hospital sends the blood vial to Labcorp on Monday and I normally get the Tac result on Friday. (That's another wonderful thing about Mayo…their lab and testing centers are extraordinary.) All in all, it was a great experience and I happily left with my new kidney! My only concern now is my elevated LIVER enzymes that are probably caused by the immune suppression drugs. My fear is ultimately they may need to further adjust or reduce my meds, which can increase the likelihood of rejection. My kidney numbers are doing so well. I wish the same was happening with the liver. I am not sure if they can just keep the liver enzymes running high without ultimately damaging the organ. I assume they are always weighing the pros and cons, similar to your awful prednisone side effects. They decided to keep you on the drug in spite of the adverse reactions. I am not sure if the liver will be same thing or if they will be forced to make an adjustment since these meds are lifetime and may cause damage to the liver after time?
I am so happy that you are through that early experience and now back to long chilly walks and dancing in the kitchen!! 💃😊💃

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I like the way you were discharged and had long term housing. Was that through Mayo? Sounds better than a hospital. But I had too many issues, or they would have booted me out earlier. Since I live alone, me and FT (feeding tube) went to friends for two weeks, before I got to go home.

You go for the MRI this week for your liver, right? Try not to worry too much. Eat healthy, watch your salt, plenty of water. And, dance! 💃🏼

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@hello1234

Hi @leahdrose 😊 No need to apologize! I am so happy to hear from you!
It's nice to hear that you have a remote part time job that you are enjoying. With covid, a remote job is perfect and recovering from the kidney transplant makes the part time hours advantageous too!
It sounds like your appointment at UCLA went well. I know what you mean about a mixed bag of good test numbers and a few test numbers that need to be watched…..That's my experience too.
It's great to know about the blood test that monitors for signs of rejection! My doctor recently mentioned a test called "Allosure" which sounds very similar to the test you mentioned. (Maybe it's just a different brand or manufacturer).
It sounds like you will continue to monitor and the good news is nothing sounds urgent. I like the idea that you will only biopsy if the blood test shows it's needed.
I was also happy to hear that you have great confidence in your UCLA transplant doctors and team. They have an excellent reputation!
Please keep me posted on your results from today and whether things are calming down or you need the biopsy.
A lot of your blood work results sound really good so I am hoping that you will be pleasantly surprised.
Will you receive the results from today's blood work this week?

Jump to this post

@hello1234. I assume today's tests include Tacrolimus, BK and CMV viruses. It takes a few days for the results to come. Last week's Tacrolimus was high, so dosage was reduced from 6 and 6 to 6 and 5. My nephro thinks the Cellcept, currently 1 and 1, is too low. However, it's the most I can tolerate. Otherwise, I'll end up again with nasty on and off infections and diarrhea. He mentioned about switching it to Mycofortic. I read it is usually given with Cyclosporine. If that's the case, I smell another adjustment. Hayst 🙁

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@leahdrose

@hello1234. I assume today's tests include Tacrolimus, BK and CMV viruses. It takes a few days for the results to come. Last week's Tacrolimus was high, so dosage was reduced from 6 and 6 to 6 and 5. My nephro thinks the Cellcept, currently 1 and 1, is too low. However, it's the most I can tolerate. Otherwise, I'll end up again with nasty on and off infections and diarrhea. He mentioned about switching it to Mycofortic. I read it is usually given with Cyclosporine. If that's the case, I smell another adjustment. Hayst 🙁

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Good morning @leahdrose 😊 I know several kidney transplant patients, including one that just celebrated his 12 year post kidney transplant anniversary (Yeah!!) 🎉 that are taking Mycofortic so don't be concerned if you are switched. They couldn't tolerate Cellcept either (all for different reasons). I didn't hear that they were also taking Cyclosporine, they didn't mention that drug too. So I am not sure if you need to take both together or not. Please keep me posted on your test results and don't be concerned if they have to switch you from Cellcept. It sounds like they are taking excellent care of you and your new kidney!
Love to you.
…. and please enjoy a very Happy Thanksgiving Holiday!! ❤

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@athenalee

I like the way you were discharged and had long term housing. Was that through Mayo? Sounds better than a hospital. But I had too many issues, or they would have booted me out earlier. Since I live alone, me and FT (feeding tube) went to friends for two weeks, before I got to go home.

You go for the MRI this week for your liver, right? Try not to worry too much. Eat healthy, watch your salt, plenty of water. And, dance! 💃🏼

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Good morning @athenalee 😊 Yes, you are correct!
This Friday morning are my liver tests to try and diagnose my elevated liver enzymes.
I think everyone is pretty confident that it's the medications that are causing it, but I think they also want to check for any damage since the enzymes have been elevated since my transplant over a year ago. I will definitely keep you posted on my results!
Also, I started Fosamax and I think it's causing even higher liver numbers and I may need to change to Prolia for my osteoporosis.
Thank you for always being so supportive Athena!!
Talk to you soon…and Happy Thanksgiving Day! ❤ I am thankful for your friendship.

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@hello1234

Good morning @athenalee 😊 Yes, you are correct!
This Friday morning are my liver tests to try and diagnose my elevated liver enzymes.
I think everyone is pretty confident that it's the medications that are causing it, but I think they also want to check for any damage since the enzymes have been elevated since my transplant over a year ago. I will definitely keep you posted on my results!
Also, I started Fosamax and I think it's causing even higher liver numbers and I may need to change to Prolia for my osteoporosis.
Thank you for always being so supportive Athena!!
Talk to you soon…and Happy Thanksgiving Day! ❤ I am thankful for your friendship.

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Happy Thanksgiving 🦃 @hello1234 my friend! I’m sending positive good liver enzymes vibes your way! Let us know what happens and what your team says.

I’ll be curious too what they say about Alendronate. It’s not supposed to interact with Tac, but does have hepatotoxicity listed as a rare side effect.

Athena 🤗

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@hello1234

Good morning @athenalee 😊 Yes, you are correct!
This Friday morning are my liver tests to try and diagnose my elevated liver enzymes.
I think everyone is pretty confident that it's the medications that are causing it, but I think they also want to check for any damage since the enzymes have been elevated since my transplant over a year ago. I will definitely keep you posted on my results!
Also, I started Fosamax and I think it's causing even higher liver numbers and I may need to change to Prolia for my osteoporosis.
Thank you for always being so supportive Athena!!
Talk to you soon…and Happy Thanksgiving Day! ❤ I am thankful for your friendship.

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@hello1234, Tests tomorrow? I'll be thinking of you and hoping for successful diagnosis of your cause of elevated liver enzymes.
@leahdrose, I have my fingers crossed that your doctors will find information in your tests so that your problem can be treated.

I look forward to hearing your updates.
I hope that you both had a pleasant Thanksgiving Day.

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