Switching from quietapine (serequil) to trazodone

Posted by ajohnstonperx @ajohnstonperx, Jun 2 2:57pm

I started off at 25mg of quietapine and it worked for a few months and then stopped working so I went up to 50mg again it worked for a while then stopped so I went up to 75mg and when it stopped working again I called my doctor to either up my dose again or try switching to something else. He told me it's quite common to switch back and forth between quietapine and trazodone so I've been on trazodone for almost a week and it has been kicking my ass. I wake up absolutely exhausted every day and I just can't seem to wake up all day. I know quitting quietapine can cause withdrawals but I was hoping switching to trazodone would make it so I didn't withdrawal. Has anyone else switched from quietapine to trazodone? How did it go? Did you withdrawal? Did it work? I'm planning on calling my doctor's "phone in" clinic on Saturday but wanted to see what other peoples experience was first. I also feel like I need to add that I have mild bipolar disorder but I am on medication specifically for that but apperently quietapine is supposed to help with that where as trazadone can actually make it worse..

Hi @ajohnstonperx and welcome to Mayo Clinic Connect. It can be frustrating when a medication that was working so well suddenly stops working.

Here is an article that references some good substitutes for serequil. It does state that no one medicine is perfect, but there are certain benefits to each one.
Top Mood Stabilizers for Bipolar Disorder: https://www.psychiatrictimes.com/view/top-mood-stabilizers-bipolar-disorder

I used to take trazodone as a sleep aide. What did your doctor prescribe it to you for?

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@amandaburnett

Hi @ajohnstonperx and welcome to Mayo Clinic Connect. It can be frustrating when a medication that was working so well suddenly stops working.

Here is an article that references some good substitutes for serequil. It does state that no one medicine is perfect, but there are certain benefits to each one.
Top Mood Stabilizers for Bipolar Disorder: https://www.psychiatrictimes.com/view/top-mood-stabilizers-bipolar-disorder

I used to take trazodone as a sleep aide. What did your doctor prescribe it to you for?

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The quietapine was prescribed for sleep, I later found out after I was off of it that it was used for bipolar disorder, and he switched me from quietapine to trazadone for sleep.

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