Strontium citrate (Algaecal) and fractures

Posted by pami @pami, Apr 15, 2024

I am looking to see if there are any studies done that show a reduced chance of fracture from using Strontium citrate (Algaecal) as opposed to calcium. Everything I have read only mentions increase of density using it. Does anyone have doctor input or a study showing an decrease in bone fractures?

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@bayhorse

Thanks for this info. I have been warned off calcium supplements by one of my docs because of cardiovascular concerns, but I believe she was thinking more of the 1,000-1,200 mg./day type supplements. I will check Algaecal to see how much calcium is included.

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A lot of people take vit k to counter any problems with calcium being depostited in the cardiovascular system.
Below is a discussion post on what Inspire posters use in terms of Vit K. Vit K is thought of as a calcium director to put calcium in your bones instead of your cardio system. Vit k is even used in some countries as a osteoporosis treatment. Might ck it out.
There are research reports (see one linked below) and even several books written about it one is: Vitamin K and the calcium paradox
https://www.inspire.com/groups/bone-health-and-osteoporosis/discussion/mk-4-mk-7-and-osteoporosis/
https://pmc.ncbi.nlm.nih.gov/articles/PMC4566462/

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@kathleen1314

A lot of people take vit k to counter any problems with calcium being depostited in the cardiovascular system.
Below is a discussion post on what Inspire posters use in terms of Vit K. Vit K is thought of as a calcium director to put calcium in your bones instead of your cardio system. Vit k is even used in some countries as a osteoporosis treatment. Might ck it out.
There are research reports (see one linked below) and even several books written about it one is: Vitamin K and the calcium paradox
https://www.inspire.com/groups/bone-health-and-osteoporosis/discussion/mk-4-mk-7-and-osteoporosis/
https://pmc.ncbi.nlm.nih.gov/articles/PMC4566462/

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@kathleen1314 Thanks for your response. The inspire.com conversation was difficult to follow, other than making the point that there's controversy re: whether K2 in the form of MK4 is as or more useful than MK7. I really really did appreciate the nih link with the article re: K2 & calcium. It backs up my doctor's order to quit the calcium supplements. Now, however, I have to determine if I'm getting enough K2. She has had me on a NuMedica supplement of D3-5000 + K2-200 (MK7), taken just 4 days a week. My levels have been good. But after reading the article, I am wondering if I ought to be taking K2 daily. Has anyone determined a maximum safe dose for K2? Does the form of K2 matter when you're figuring maximums? Perhaps I should be taking some MK-4 on the days I don't take my NuMedica supplement.

I do worry about calcium deposits in soft tissue as well as from the standpoint of cardiovascular risk because I have had to have 3 breast biopsies (fortunately benign results)due to calcifications. This just keeps happening. The breast doc says there's nothing I can do to prevent this, but I am wondering whether extra K2 would help. Just don't want to overdo!

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@bayhorse

@kathleen1314 Thanks for your response. The inspire.com conversation was difficult to follow, other than making the point that there's controversy re: whether K2 in the form of MK4 is as or more useful than MK7. I really really did appreciate the nih link with the article re: K2 & calcium. It backs up my doctor's order to quit the calcium supplements. Now, however, I have to determine if I'm getting enough K2. She has had me on a NuMedica supplement of D3-5000 + K2-200 (MK7), taken just 4 days a week. My levels have been good. But after reading the article, I am wondering if I ought to be taking K2 daily. Has anyone determined a maximum safe dose for K2? Does the form of K2 matter when you're figuring maximums? Perhaps I should be taking some MK-4 on the days I don't take my NuMedica supplement.

I do worry about calcium deposits in soft tissue as well as from the standpoint of cardiovascular risk because I have had to have 3 breast biopsies (fortunately benign results)due to calcifications. This just keeps happening. The breast doc says there's nothing I can do to prevent this, but I am wondering whether extra K2 would help. Just don't want to overdo!

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Firstly, the best way to read the Inspire post is not to get lost in the replies, but to read the post which has enumerated several of the best thoughts in the posting.
Next, let's talk about your calcium; you need to know if you are getting enough calcium. Let me suggest that you look at your dietary intake by using cronometer; they have a simple daily input program that will tell you about not only your calcium intake but most of your nutritional intake. Ck it out; you may not need any calcium supplemention or you may just need a little.
But now in case you do need more calcium you can either go the dietary route or take some supplements.
But I think that you are missing from the research that no matter how you fill your calcium needs if your body is putting that calcium in your cardio system instead of in your bones etc. then you have a problem.
The calcium/cardio problem is not tied to just to supplementation. It is amplified by supplementation. Supplementation only has the potential of making your existing problem worse, attentuating it, as the research says.
That calcium/cardio problem, if you have it, is that your body is not regulating your calcium well and is putting it in places where it is dangerous for you.
Vit k regulates calcium; it is the traffic cop for calcium and puts it where it is more likely to help and not hurt you. The research paper points this out by saying "because some evidence points to health problems at elevated levels.
That issue could be remedied, however, if the right amount of vitamin K2 were to be added to a high-calcium regimen. Vitamin K2 promotes arterial flexibility by preventing accumulation of arterial calcium,10,47,62 and supplementation with it could correct calcium amounts in the body that are out of balance. Thus, calcium in tandem with vitamin K2 may well be the solution for bringing necessary bone benefits while circumventing an increased risk for heart disease."
The recommended dose for mk7 for patients in the book was 200-240mcg daily. Daily recommended amount is more like is 150 to 180 µg per day.
The 200mcg seems to be what you are taking in your NuMedica supplement of D3-5000 + K2-200 (MK7).
Note on the Inspire discussion that many replies mentioned syncopations as a possible side effect of vit k. Because of this many posters obtain their vit k thru their diet as much as possible.
Calcium deposits in your breast may show that you are prone to deposit calcium, but they may just be caused by lots of other benign conditions which have nothing to do with your cardio system.
Still, there is some research connecting the two: https://www.ahajournals.org/doi/10.1161/CIRCIMAGING.121.013526

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to pami
here you find the articles on strontium effect on fractures
https://pubmed.ncbi.nlm.nih.gov/14749454/
https://pubmed.ncbi.nlm.nih.gov/15728210/
However, there are some data about strontium causing CVD and also thrombosis. I am about to start taking it, but
afraid of these negative effects.

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@melia7

to pami
here you find the articles on strontium effect on fractures
https://pubmed.ncbi.nlm.nih.gov/14749454/
https://pubmed.ncbi.nlm.nih.gov/15728210/
However, there are some data about strontium causing CVD and also thrombosis. I am about to start taking it, but
afraid of these negative effects.

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Are you going to take strontium renelate or strontium citrate? I am not sure they have the same effect on bone. I listened to a podcast about strontium citrate. He said it doesn't fill in the bones like calcium. I also know from my sister taking it and then quitting that you lose all the density you gained when you stop. I hope it works for you. I am still apprehensive about fracture risk.

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There were 2 small studies using strontium citrate along with other micronutrients. One from Canada was the COMB study the other was from Duquesne University in the US which was more detailed in that they looked at the bone composition. They both showed reduced fractures and bone strengthening similar to Fosamax. I thing it was called the Mots study. I used the recommendations from both , in part, and I reversed my osteoporosis to osteopenia while taking prednisone. I plan to continue. Calcium
was dietary.

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@pami

Are you going to take strontium renelate or strontium citrate? I am not sure they have the same effect on bone. I listened to a podcast about strontium citrate. He said it doesn't fill in the bones like calcium. I also know from my sister taking it and then quitting that you lose all the density you gained when you stop. I hope it works for you. I am still apprehensive about fracture risk.

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I am going to use strontium citrate but first I decided to check my heart, etc. My father had infarcts and thrombosis and I do not want to increase my risks of this.

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@karenjaninaz

There were 2 small studies using strontium citrate along with other micronutrients. One from Canada was the COMB study the other was from Duquesne University in the US which was more detailed in that they looked at the bone composition. They both showed reduced fractures and bone strengthening similar to Fosamax. I thing it was called the Mots study. I used the recommendations from both , in part, and I reversed my osteoporosis to osteopenia while taking prednisone. I plan to continue. Calcium
was dietary.

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Could you please post those links to the two small studies please?

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@karenjaninaz

There were 2 small studies using strontium citrate along with other micronutrients. One from Canada was the COMB study the other was from Duquesne University in the US which was more detailed in that they looked at the bone composition. They both showed reduced fractures and bone strengthening similar to Fosamax. I thing it was called the Mots study. I used the recommendations from both , in part, and I reversed my osteoporosis to osteopenia while taking prednisone. I plan to continue. Calcium
was dietary.

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You mean that you took strontium at the same time when you used prednisolone?

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Yes I’ve Been on prednisone since 2014 for polymyalgia rheumatica .

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