Statins & Praluent my experience and a NEW GENERIC STATIN

Posted by kallettla @kallettla, May 23, 2025

I tried generic Lipitor and it gave me terrible leg cramps. They went away within just a few days after I discontinued them. Then I tried 10 mg generic Crestor and body aches crept up on me. I was sore to the touch. I thought I needed to go to PT. Then, I tried stopping them and the body aches went away within a week.

Onto Praluent. I have high LP (a) and my Dr said it was well tolerated, unfortunately, not by me. I had symptoms I described in an earlier post. After my second injection, I had an allergic reaction. I have Mast Cell Activation Syndrome and often have allergic (anaphylaxis) reactions to fragrances. This was the first time I had an actual allergic reaction to a medication. I described details in a former post.

I contacted my Dr, allergist, and pharmacist. I believe pharmacists know more about drugs than Dr's and so does ChatGPT in many instances. No one knows what it could have been...active ingredient or inactive that gave me the allergic reaction.

What I want to tell you is that I am going to try Crestor once a week. If that doesn't work out ....my pharmacist said there is a statin that just became generic that doesn't have all the side effects of the others! He said it is very powerful and so it has low mg. It is called PITAVASTIN.

Has anyone tried it?

Interested in more discussions like this? Go to the Heart & Blood Health Support Group.

Maybe I will bring up to cardiologist as my advanced lipid profile is bad. Praluent is an injectable like Repatha I believe. My insurance doesn't cover it. I was on Zetia and Repatha and Zetia just wouldn't bring down my cholesterol but was always floating close to normal. Repatha was awesome until I just couldn't take the on andf off nausea, fatigue and muscle pain. I did drop a few pounds from not eating. Doctors say it doesn't have myalgia symptoms, but it exacerbated the pain I already had. It is hard to tell what a side effect is and what is something you have that is just worse. I had such a horrible time with statins that now I don't know what is my autoimmune and what is a medication side effect. I have been off all cholesterol for just 4 weeks and most pain has subsided. Still have hip, upper back and legs.

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