1. < Women's Health

spotting then bleeding after knee injection for injury

Posted by lee60 @lee60, Jul 1, 2022

I am 63, menopausal for 8 years. One episode abnormal vaginal bleeding in late 50's d/t taking BHRT. Ultrasound and endometrial biopsy results normal. 10 days after receiving 80mg Kenalog in knee joint started spotting and now on day 15, bleeding is heavier. No other symptoms like cramping, bloating etc. Stopped BHRT 2 years ago. Anyone experienced this? Any suggestions on what to do?

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Mentor
Lori, Volunteer Mentor | @loribmt | Jul 2, 2022

Hi @lee60, well that has to be rather unnerving. This is pretty late in the game to have any spotting or bleeding. In my opinion, if you’ve been menopausal for 8 years and are experiencing any type of unusual symptoms from your reproductive system, I’d say, hightail it to your gynecologist to have this checked out ASAP. Your ultrasound and biopsy are no longer current so you really need to have this new development evaluated.
Will you please make an appointment to put your mind at ease and then let me know?

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1 reply
lee60 | @lee60 | Jul 3, 2022
In reply to @loribmt "Hi @lee60, well that has to be rather unnerving. This is pretty late in the game..." + (show)
@loribmt

Hi @lee60, well that has to be rather unnerving. This is pretty late in the game to have any spotting or bleeding. In my opinion, if you’ve been menopausal for 8 years and are experiencing any type of unusual symptoms from your reproductive system, I’d say, hightail it to your gynecologist to have this checked out ASAP. Your ultrasound and biopsy are no longer current so you really need to have this new development evaluated.
Will you please make an appointment to put your mind at ease and then let me know?

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Thanks for your comment! I'm planning to do just that. My regular gynecologist retired 2 years ago and I'm having to find one (which I SHOULD have done when he did, lesson learned). I've been a nurse for over 40 years so I have heard of this bleeding happening after cortisone shots, just never seen it. Curious as to how often it happens considering the number of people that get these shots to help with joint pain. Will keep you posted!

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1 reply
Mentor
Lori, Volunteer Mentor | @loribmt | Jul 3, 2022
In reply to @lee60 "Thanks for your comment! I'm planning to do just that. My regular gynecologist retired 2 years..." + (show)
@lee60

Thanks for your comment! I'm planning to do just that. My regular gynecologist retired 2 years ago and I'm having to find one (which I SHOULD have done when he did, lesson learned). I've been a nurse for over 40 years so I have heard of this bleeding happening after cortisone shots, just never seen it. Curious as to how often it happens considering the number of people that get these shots to help with joint pain. Will keep you posted!

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Oh wow, that’s really interesting! I’ve never heard of bleeding as a side effect from cortisone shots. But you sparked my curiosity and I was surprised by the number of articles which popped up stating just that! I learned something new.
But I’d still have that checked out. ☺️

I scanned our Connect site and look what I found! Another member with your similar experience! Meet @toromama. I’m not sure she’s signed into Connect at this time but you might find her post relevant.
https://connect.mayoclinic.org/discussion/spotting-following-cortisone-injection/

REPLY
sadie1967 | @sadie1967 | Aug 31, 2023

Hello!
I began getting cortisone shots in my knees last spring, and have had them multiple times since.
11 days after first round of shots, I started my period after being 2 years into menopause.
The orthopedist and clinic had never heard of this. My doctor had never heard of this. After multiple tests and biopsies it was determined to be a side effect.
I had shots last week, and guess what started when I woke up today?!
There is so little information on this correlation - but I'm here to tell you, it exists.
It is a bummer side effect, but it is worth it so I can move comfortably. Hot flashes, maxi pads and all 🙂

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1 reply
lizzyleolee | @lizzyleolee | Mar 17 6:09pm
In reply to @sadie1967 "Hello! I began getting cortisone shots in my knees last spring, and have had them multiple..." + (show)
@sadie1967

Hello!
I began getting cortisone shots in my knees last spring, and have had them multiple times since.
11 days after first round of shots, I started my period after being 2 years into menopause.
The orthopedist and clinic had never heard of this. My doctor had never heard of this. After multiple tests and biopsies it was determined to be a side effect.
I had shots last week, and guess what started when I woke up today?!
There is so little information on this correlation - but I'm here to tell you, it exists.
It is a bummer side effect, but it is worth it so I can move comfortably. Hot flashes, maxi pads and all 🙂

Jump to this post

Same here...I am at the biopsy phase waiting for result. I spotted 10 days post injection and had 2nd injection and am spotting again 10 days later. My ultrasound showed 6/7mm lining so she wanted biopsy. Did you have a thickening of the uterus lining?

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2 replies
patmastcomcast | @patmastcomcast | Mar 18 7:33am
In reply to @lizzyleolee "Same here...I am at the biopsy phase waiting for result. I spotted 10 days post injection..." + (show)
@lizzyleolee

Same here...I am at the biopsy phase waiting for result. I spotted 10 days post injection and had 2nd injection and am spotting again 10 days later. My ultrasound showed 6/7mm lining so she wanted biopsy. Did you have a thickening of the uterus lining?

Jump to this post

I also had spotting after hip injection. Endometrial lining went up from over 4 to eventually 8. I had neg biopsies but was talked into a hyscopy d and c. Only had 2 small polops everything negitive. I havnt had anymore shots since august,almost 8mths ago and no spotting. Go figure.

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1 reply
sadie1967 | @sadie1967 | Mar 18 7:43am
In reply to @lizzyleolee "Same here...I am at the biopsy phase waiting for result. I spotted 10 days post injection..." + (show)
@lizzyleolee

Same here...I am at the biopsy phase waiting for result. I spotted 10 days post injection and had 2nd injection and am spotting again 10 days later. My ultrasound showed 6/7mm lining so she wanted biopsy. Did you have a thickening of the uterus lining?

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That is exactly my journey! It was showing 7mm so they did some biopsies and they came back clear. So now I just expect to have a period after the shots. It’s so weird!

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1 reply
lizzyleolee | @lizzyleolee | Mar 18 1:13pm
In reply to @sadie1967 "That is exactly my journey! It was showing 7mm so they did some biopsies and they..." + (show)
@sadie1967

That is exactly my journey! It was showing 7mm so they did some biopsies and they came back clear. So now I just expect to have a period after the shots. It’s so weird!

Jump to this post

Just got the call this morning from nurse! Benign findings...so weird is right!

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lizzyleolee | @lizzyleolee | Mar 18 1:16pm
In reply to @patmastcomcast "I also had spotting after hip injection. Endometrial lining went up from over 4 to eventually..." + (show)
@patmastcomcast

I also had spotting after hip injection. Endometrial lining went up from over 4 to eventually 8. I had neg biopsies but was talked into a hyscopy d and c. Only had 2 small polops everything negitive. I havnt had anymore shots since august,almost 8mths ago and no spotting. Go figure.

Jump to this post

It is a rare side effect, apparently. I guess it is better that they don't say it is possible cause some women may not call their gyno for check up. Although scary to have the biopsy and wait, I definitely feel relief knowing why I am having the spotting. 🙂

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