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What helps to slow testosterone growth?
Good afternoon, dear friends.
I'm 49 years old. My cancer is genetic (ATM gene mutation).
Three years after diagnosis, initial PSA 530 (Gleason 4+5), three bone metastases, and metastases to the pelvic, cervical, and pulmonary lymph nodes. The prostate is still there, but they didn’t perform surgery on me because the doctor said it was dangerous.
Chemotherapy and ADT (Zoladex 10.8) began in May 2024
I completed eight chemotherapy sessions over six months and Zoladex 10.8 injections. After chemotherapy (October 2024), my testosterone level was 1.1 and has been slowly increasing throughout 2025 despite switching to Diphelerin 3.75. My testosterone level is 1.61 (as of November 2025).
Six months after the double combination of chemotherapy and ADT (Zoladex 10.8), I was given Erleada , start February 2025
My urologist-oncologist isn't alarmed and says everything is fine. He says I can try going back on Zoladex 10.8, but another specialist says I should stay on the medication I take monthly (Diphelerin 3.75). For now, I'm taking it monthly (once every 28 days).
I've heard that testosterone levels should be below 0.7 to minimize risks.
Furthermore, I'm told that if my testosterone levels rise to 1.7, I'll need to have my testicles removed.
PS I've noticed that my testosterone levels have slowed down recently over the past 4 months, reaching 0.06. 1.55 - August 2025, 1.61 - November 2025
Please share any advice or thoughts on what I should do.
1. Continue taking diphereline 3.75
2. Change the ADT drug to a different one
3. Immediately demand removal of my testicles
4. Other options
I've now introduced testosterone-lowering foods into my diet, such as green tea (3 cups a day), mint, and licorice root. I cut out sex completely and started moving less.
I'm terrified of the tests scheduled for mid-January 2026 🙁
Thank you very much, and stay healthy 🙂
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Hello 2 All Friends! Guys!
I got tested yesterday:
My testosterone up to 1.4 from 1.0, my PSA continue to fall - 0.02.
I haven't changed my medications.
Why is my testosterone fluctuating up and down? 🙁
I have to admit, for four months I've been quitting my diet and eating everything, mostly meat, ice cream, and fast food.
I'm confused as to what's causing my testosterone again lite to rise.
@jeffmarc
Dear Jeff, what do you think is happening?
@denis76 From 1 to 1.4 is really nothing to worry about when it comes to T.
T can rise after exercise as well…but at these castrate levels, you are really fine.
Phil
@denis76
I am not sure if you are measuring testosterone With nanograms per deciliter (ng/dL) in the U.S., or nanomoles per liter (nmol/L) international.
1.4*28.85=40.39 Ng/dL
Figuring you were using the international measurement a 40 Testosterone is pretty darn high For someone on ADT.
I’m wondering if you’ve had genetic testing? I know that one other person had the same problem because they had a genetic problem of ATM, which made it so that Androgens like Lupron didn’t get their PSA down correctly, But antiandrogen’s like Firmagon did work properly.
There is another possibility, however. Your body may just be becoming Resistant to the ADT type, you are on now. I’m having that exact problem, I’ve been on Orgovyx For three years and my Testosterone is starting to rise. I may have to switch over to Lupron to see if it will make a difference. Just depends on what the blood test show over the next few months.
Talk to your doctor about androgen versus antiandrogen versions of ADT drugs, and whether a change may be needed for you.
Good to hear your PSA is not changing, At least you are not becoming Castrate resistant.