Slow testosterone growth

@jeffmarc I suspect his testosterone is being measured in nmol/L, not ng/dl. So you would multiply ny 28.8 to convert. So 1.7 would be about 49

@jeffmarc

You real fighter, Bro!

\\ I did stop taking Orgovyx For eight months.

At what point in time? I mean, before resistance?
And what was the PSA status over the next 8 months?

\\After 19 days on only three pills, my PSA went from .2 to 1. That’s an 800% increase in 19 days.

Let me correct you, Bro 500% 🙂 (1/0.2)x100%
mmm, nighmare speed. Honesty, I dont understand why, with low PSA there is a small number of cells, no?

\\I was on Zytiga for 2 1/2 years and have been on Nubeqa For almost 3 years. Nubeqa Will fail eventually, and I will go on a PARP inhibitor after that.

OMG, Erleada will protect me for only about 1-1.5 years 🙁 My doctor predicted that Erleada would work for at least 5 years and even with a resistance phase

Have you had prostate removal surgery?

How did the cancer start: stage, initial PSA, metastases?

Regarding genetics and aggressive cancer.

It's harder for younger people because our cells divide faster 🙁

Do you think the saying "Don't make it angry and give it some fuel instead of completely blocking it" applies to cancer? Maybe it really does transform into an ultra-aggressive form only because it's being "tormented." In other words, cancer's aggressiveness is proportional to the aggressive measures taken. What if you give it fuel in portions, as if calming it down? The metaphor is certainly silly and crude, but I think you understand what I mean. That's exactly what I saw in your story, am I wrong?

\\After seven years on ADT,
\\I was on Zytiga for 2 1/2 years and have been on Nubeqa For almost 3 years.

Have you been taking only ADT for 7 years? Without Zytiga?

Let me ask you,

How tall are you? What was your weight like at the beginning of your cancer, in the middle (after 8 years of illness), and now? Are you thin? Is your body fat low? Is your muscle tone high?

How far do you run? Long runs to the point of exhaustion? What kind of strength training, endurance training?

Do you get nervous often? Where do you live? In the city or in the countryside, in the fresh air? Damn, sorry, Bro, but do you have sex or not? Thanks so much for the answers!

Amazing story! I'm still in shock that you're fighting cancer so hard! You're special!

@denis76
Is this true Denis
“ suspect his testosterone is being measured in nmol/L, not ng/dl. So you would multiply ny 28.8 to convert. So 1.7 would be about 49”

If that is true, and that is what is happening, then I can see why the doctor wants to remove the testicles. He could try putting you on Zytiga instead of Erleada. It does reduce testosterone further than ADT, but that may not be enough. I’ve only heard of one or two other cases like this where the testosterone doesn’t get dropped to at least below 20.

Actually Erleada does not drop testosterone at all.

I brought this subject up earlier. Even if you have testosterone. Erleada suppresses testosterone so that it does not allow the prostate cancer to use it. So it keeps the PSA down with testosterone.

@jeffmarc

Does Zytiga work the same way as Erleada?

By the way, Jeff, I should tell you. Back when my testosterone level was 1.1, I was very active. I'd get up early in the morning, run 3 km, and walk a lot throughout the day. I walked a lot and did a lot of exercise. I was so tired that at lunch, I'd fall over and sleep for an hour.

Six months later, I changed my lifestyle: I stopped running, stopped walking a lot, and stopped exercising. I'm constantly sitting at home and moving little.

The question arises: did the lifestyle change affect my testosterone? And is there a concept of testosterone utilization with movement? In other words, should I exercise daily or sit still and move little, what do you think?

Besides changing my lifestyle, I changed my diet and started eating everything in sight (meat, ice cream, and everything else). Again, could this have had an effect?

And finally, my testosterone levels haven't changed over the past four months, and the change was 0.06, which seems to be a measurement error. Perhaps I'm wrong in my reasoning regarding the onset of cancer resistance; in fact, my testosterone levels have plateaued. I usually get my testosterone levels tested in the morning, when they're at their highest. Maybe I should get them tested in the afternoon instead? Plus, I've been completely abstaining from sex for two years now. What would happen if I started again? Is there a concept of testosterone depletion?

My erectile function is perfectly fine but I read that prolonged abstinence from sex reduces testosterone synthesis and production, but there are other risks, such as blood stagnation in the genital area and other side effects. I chose abstinence as part of my strategy.

Thank you.

@denis76
Zytiga goes to all of the places that create testosterone in your body and shuts them down. It also has a lot more side effects than Erleada. Those probably wouldn’t be a problem for you since you’re so young. It’s just that your testosterone is so high that I am not sure it would make a significant difference.

If you were riding a bike or any other type exercise equipment that was pushing against your perineum that can raise your PSA a little, But not very much. Maybe .1.

If you are running heavily, it can raise your testosterone walking is unlikely to make any change at all. What you eat will have a minimal effect on your testosterone level.

You should continue to be active and running if possible. ADT causes a lot of fatigue and the way to get around it is to exercise. That’s why I run on the track twice a day. That’s another reason I go to the gym three times a week. Not only will your muscles deteriorate when you are on ADT, but you get fatigue which can be offset by the exercising. I know it sounds like it doesn’t make sense, but it is true and it’s something that we talk about in the online meetings all the time.

Having sex is not a problem if you don’t do it two days before getting your testosterone checked. Even right after it only makes a small change in your testosterone level. The way they measure it where you are it probably would make, at the most, a .1 difference.

@jeffmarc

\\ It’s just that your testosterone is so high that I am not sure it would make a significant difference.

Yes, but how can we determine the cause of elevated testosterone levels? Cancer or other factors?

Let me remind you that my doctor, after seeing my testosterone and PSA results, told me that my PSA and testosterone levels were stable and recommended eating foods that lower testosterone. My doctor is a very skilled specialist and works at a leading medical center.

My only concern is that despite changing medications, my levels are slowly rising and not falling, although they should be falling because I'm taking ADT and Erleada. Does this mean I started Erleada too late and the cancer is too late to stop?

I understand there are no answers to my questions. If Zytiga is truly stronger than Erleada, then I need to quickly quit and demand an oncology consultation. Otherwise, I have no chance.

Our healthcare system simply can't physically prescribe Zytiga to me because there's no funding and "they'll send me into space with my monstrous problem."

Yet Zytiga is sold here, but I can't buy it without a prescription! What a contradiction! Double standards: some people can take it, while others can't!