Mayo Clinic Connect
I am wondering how fast it generally takes for one to feel the benefits of Sinemet? Thx.
Liked by Teresa, Volunteer Mentor
Hi Susan, @susan62
Well, when I started my doctor did a titration start-up. First week, I took 1/2 tab, once a day. Second week, 1/2 tab, twice a day. The third week, I was suppose to take 1/2 tab three times a day. However, before the end of the second week, I felt like I was missing something so I started taking 1/2 tab three times a day and was beginning to notice a difference.
How are you starting the Sinemet? Are you noticing any difference yet? What dosage are you taking 25/100?
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Hi Teresa. Just started Sinemet yesterday. I am to take 1/2 tab twice a day for a week then 1/2 tab three times a day. I am to call her in 25 days. I went for a PT evaluation yesterday and discussed a treatment program with the PT gal. She was WONDERFUL! She was so encouraging and upbeat. For the first time since being diagnosed with PD I have felt really hopeful. She said I was a good candidate for an intensive treatment program that is 4 times a week for 4 weeks. I am definitely going to do it. She also gave me a number of exercises to do to start off with. She is a Godsend!
Such good news! I'm glad that you feel encouraged. I agree with you that PTs are the best! You sound highly motivated to help yourself and that is helpful to your medical team as well.
Keep up the great work and especially the great attitude. Will you keep in touch and let me know how the Sinemet and PT are working for you?
Most certainly! You and the other PD patients are very helpful!
Hi Teresa. Your Sinemet regimen seems to be very similar to what my doctor has prescribed for me. I am now taking 1/2 tab twice a day for a week which will end on Friday. Then on Friday I am to take it three times a day. What times do you take it each day! The 1/2 tab twice a day isn’t doing much if anything. I will see a neurologist at the Mayo on the 5th of Sept. The Sinemet is what my neurologist who is in Minneapolis prescribed.
Well, I now take a full tab 2 times a day and in the middle of the day I take a Stalevo. The Stalevo is Sinemet plus an added ingredient (entacapone) to make the Sinemet last longer.
You are still on a low dose with just a 1/2 tab twice a day. It is always better to start slowly and work up. Once you see the Mayo doctor you should have a better idea if it is working for you. While Sinemet is the gold-standard for PD there are other meds that you can try. It is quite early in your treatment just now.
What areas of symptoms are you still experiencing?
Liked by Lisa Lucier, Connect Moderator
Thx again Teresa
@susan62 I'm glad to share my experiences with you, Susan. Keep asking questions when you feel concerned!
As I recall you have an appointment coming up soon at Mayo. How are you feeling after taking the Sinemet for a while now? Are you noticing any difference?
Have been taking the Sinemet for 10 days now on the 1/2 tablet 3x a day, as per the Neurologist I have seen in Minneapolis. Pain seems a little better during the day, but in the evening and at bedtime it is not good. Particularly when I go to bed. Honestly it is wearing me down. Will have an EMG on Weds and then see another Neurologist on Thursday at the Mayo. Sincerely pray that he will be able to help me with the pain. I continue to walk 3+ miles a day, garden and keep quite active. With be involved with the Big and Loud Program for the month of November. Thx for your concern.
It is good to hear from you. I hope that your appointment with the doctor at Mayo will offer you some help with the pain problem. Some adjustment in the meds may be necessary, but the doctor can figure that out.
Do you have a lot of stiffness first thing in the morning? I hope to hear from you again after your appointment.
I feel the most like myself before being diagnosed with PD in the morning before I get out of bed. I would not say that I feel stiff. Slowly the discomfort and pain starts to creep back into my arm. As I think I have said, the pain takes different forms, from an electrical small buzz to a sharp pain, to a strong ache, to pins and needles, to a burning and to a twisting. It moves around and comes and goes. The twisting feeling is the worst. It is this pain that wears on me the most. I still excercise and keep very active. I can deal with the rest of the symptoms, but honestly it is this pain that makes it hard to keep positive.
Yes, I will let you know how my appointments go. Communicating with you helps a lot.
Liked by Teresa, Volunteer Mentor, Lisa Lucier, Connect Moderator
I agree. The twisting feeling is the worst. My main area of pain is my right thigh. That is where I have the twisting, pins and needles and cramping occurs. I hope you get relief soon.
I have been thinking about you. As I recall, you had an appointment at Mayo last week. If you are comfortable sharing about that appointment, I would love to hear if you were offered any new suggestions or help with your current pain problem.
Hi Teresa. Thx for your continued interest. I had an EMG when I was down at the Mayo last Wed and I have no nerve damage. Hallelujah!!! I then saw a neurologist on Friday. He was WONDERFUL!!! I can’t say enough about how wonderful the Mayo Clinic is and everyone there is so helpful and concerned about helping you. I could tell you numerous very positive stories of family and friends experiences there too. Anyway, the doctor said that I am at the very beginning stage of PD and that I was getting a very low dosage of Sinemet. He increased the dosage which I am doing gradually every day. He feels confident that it should help with the pain in my arm. He said to call him if it doesn’t respond. Otherwise I am to see him again in 2 1/2 months. He strongly encouraged me to continue to be active by walking 3 miles daily, gardening and generally staying active. No problem on that with me. He also said that with the medication, excercise and working the Big and Loud Program I should have 10-20 years where my symptoms don’t change much. THAT made both my husband and me very hopeful. If one can, I STRONGLY encourage anyone who has some disease or major health issue to go to the Mayo. It’s good for your body and your mental health.
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