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Reclast infusion long term side effects

Posted by tiza @tiza, Feb 4 7:41am

Hello,
I’m new to this forum.
I had a Reclast Infusion in May 2025. After a year dealing with knee pain issues my Dexa Scan results were terrible.
My endocrinologist had already suggested I’d need it, after doing some research I refused it for about 5 years.
Since the infusion, I’ve had digestive problems and pain on my left ribs. Strangely, on the first 24 hours after the infusion this is the exact place where I had intense sharp pain. It’s mostly during the night and in the morning.
Anyone experiencing the same?
Thank you!

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Davi Ford | @davi73ford | 18 hours ago
In reply to @tummis05 "2 weeks before I was due for Reclast infusion I learned I needed a tooth extracted..." + (show)
Profile picture for tummis05 @tummis05

2 weeks before I was due for Reclast infusion I learned I needed a tooth extracted and a bridge put in. The endocrinologist said to not reschedule Reclast until all the dental work was completed. I come from a family of dentists and dental hygienists. They have all told me NOT to do Reclast. Even the oral surgeon that extracted my tooth was lecturing me (angrily) on not doing it. I have a temporary bridge right now and soon getting the permanent one put in and I have had a lot of time to think about Reclast and decided against it. The risk isn't worth the reward bcz there doesn't seem to be any reward in doing it! When I first saw my endocrinologist she asked me if I had heartburn or stomach issues and bcz I said I had heartburn she said I have no option but to do the Reclast. I am weary of this response also. How bad are the oral meds for us folks with occasional heartburn? Are the endocrinologists told to push the Reclast on their patients?
I have a bone scan and appointment with endocrinologist in May and at that time I have to re-evaluate this whole situation. I am having a hard time believing that there is a medication that can restore bone health. Can anyone make me a believer?

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@tummis05
I had 2 of the 3 Reclast imfusions. After the first, but before the second, I began having dental problems. At that time, I did not associate it with the Reclast. After my 2nd infusion, my dental problems escalated. I now have had both canines and a couple of other teeth removed. I currently have several teeth in stages of decay, along with teeth that are in various stages of breakage, and now my bridge is loosening. I can also feel with my finger, the bottom ridge of my teeth where the gum is receding. And, while not being actually diagnosed with it, it has been suggested that I may also have Osteonecrosis. Within the past few days, I have noticed a swollen gland right at my jawbone, which hurts when touched, and the pain goes up into my bone and teeth on that side. Needless to say, I refused the third infusion of Reclast, and am searching for a dental specialist (unsure of proper dental title). For diagnosis and treatment. I think you made a very wise choice to refuse Reclast!

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kristie2 | @kristie2 | 10 hours ago
In reply to @maine "There is no medication that can restore bone health. Period. The gain from Reclast is temporary...." + (show)
Profile picture for maine @maine

There is no medication that can restore bone health. Period. The gain from Reclast is temporary. You can only have the infusion ONCE. Then the next year they will be pushing a different infusion while you're still reeling from the side effects of the first one. I've been there, my advice is don't do it.

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@maine The infusion is once a year for 3 years for reclast. I have had one so far with no side effects so far. I’m debating if I will continue. I had Evenity and then Prolia for 2 injections and now reclast. Hopefully my next DEXA will be better and allow me to see if my hormone replacement will give me enough protection.

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