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Recently started Bupropion (Wellbutrin)

Posted by lalyfa @lalyfa, Jul 3, 2018

3 months ago I started taking Bupropion XL 150mg. It seemed to help me in several ways and I was happy with it. No “fuzzy” brain feeling, I woke up in the morning feeling refreshed, eliminated no reason crying spells, etc. I thought I could use a little stronger strength but I didn’t want to increase unless I really needed to. Since I made progress with the 150mg I decided to stay there! Then about 10 days ago a family situation occurred which sent me in a tail spin! Finally, settled done from that then I had a big issue with my mentally-challenged brother who lives with me (I am his caregiver). Since then I feel like the Bupropion is not working as it was. Crying a lot for no reason, waking up in the morning feeling terrible, no motivation. Is it normal for this to happen where I felt better than have a set back? I am now going to increase to 300mg to see if that helps. I don’t like to have to increase my anti-depressant dose but hopefully this will be the right dose for me! Again I’m just curious if anyone else went through something like this?

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mikekennedy759 | @mikekennedy759 | Jan 15, 2024
In reply to @danielledep "I started Bupropion XL (150 mg) almost seven weeks ago. Is it possible to start experiencing..." + (show)
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I started Bupropion XL (150 mg) almost seven weeks ago. Is it possible to start experiencing new side effects at the six week mark?

About three days into my sixth week I started randomly having a tremor in my left hand when I gripped something tight. It stopped after about half an hour but I still felt “shaky” for a few days in my arms and hands. Now five days later and I had a quick bout of shaking and tremor in my right hand and not while gripping. I can describe the feeling as how it feels when your foot or hand falls asleep and you’re getting the sensation back. I feel that way in my arms and hands mostly. When I wake up my legs do also feel a bit shaky.

I’ve read that tremors can be a side effect, but is it common for this to develop after you’ve already been on the medication for six weeks without experiencing this up until this point?

I made a doctor’s appointment to rule anything serious out, but it only just came to me that maybe it’s a result of the medication.

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danielledep @danielledep

Like Laurie said, it takes time for the medication to starting functioning in your body. Usually weeks. I have had some minor symptoms like dry mouth and irritability. I have had tremors, but I might have them from some other condition.

I remember who I was before the medication so I have been ok with it. It is good that you are talking to your doctor about it. Never be afraid to do so. Remember, everyone has different reactions to medications.

For what its worth, a psychiatrist friend of mine recommended Wellbutrin/Bupropion as an anti-depressant for me. He does not treat me, but I sometimes turn to him (and he checks on me) for a second opinion/guidance if I have any concerns.

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