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Rare serious side effect of Eliquis: Muscle weakness

Posted by cmauncc1 @cmauncc1, Dec 27, 2021

In late July 2017 I was admitted for very high heart rate and Afib. Had been, and still am, on minimal meds. Hospitalist put me on Eliquis, 5mg 2X/day.

Within a month my leg muscles were weakening to the point where I could no longer play Pickleball or walk golf. Within a few weeks my Cardiologist did an ablation and inserted a loop recorder. For the next 2-1/2 years the loop recorder saw MINIMAL Afib, under 0.5%; the ablation did its job.

By November 2017 I needed a walker. By December 2017 I needed to be wheelchair pushed through an Ice Sculpture display as there was no way I could walk the 25-30 minutes of the exhibit.

When I finally got to see a Neurologist at Shands (Univ of FL, Gainesville) in July 2018, he ran an extensive battery of blood work tests but could find nothing to explain the muscle weakness.

Has anyone else encountered similar muscle effects following being prescribed Eliquis?

Interested in more discussions like this? Go to the Heart Rhythm Conditions Support Group.

techcat50 | @techcat50 | Jan 5 12:12pm
In reply to @sandy811jakester "For 2 years I experienced my legs weakening. My legs would give out for no apparent..." + (show)
@sandy811jakester

For 2 years I experienced my legs weakening.
My legs would give out for no apparent reasons. After many tests, my neurologist suggested an MRI of my thoracic spine and they found a cyst. He referred me to a neurosurgeon who removed the cyst and fused t4-t7. That was in Feb of 2023.

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Hi, how are you doing now after the surgery?

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1 reply
sandy811jakester | @sandy811jakester | Jan 5 12:53pm
In reply to @techcat50 "Hi, how are you doing now after the surgery?" + (show)
@techcat50

Hi, how are you doing now after the surgery?

Jump to this post

Doing well.
Legs have not given out since surgery. Had to wear a brace for about 2 months. Then back stimulator for about 10 weeks.
Using a cane to walk due to balance but all in all happy I had it done

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techcat50 | @techcat50 | Jan 5 1:17pm

Thanks for the update. Glad you're doing well. I'm considering vein ablation as well.

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joaf37 | @joaf37 | Jan 6 8:34am

Me as well .. these comments today were of special interest.

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cominer1 | @cominer1 | Jan 10 4:32pm

HOW OLD ARE THESE COMMENTS ABOUT ELIQUIS ? 2024 OR 2025

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timheart1 | @timheart1 | 6 days ago

Hi I replaced Eliquis w/ Garligin form Natural Slim. Garlic and ginger capsule, take 3 times a day. I have been on it for years, it works fabalous as a blood thinner with no side effects. I know is works because if a cut myself I bleed and bleed.

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