Prolia treatment for osteoporosis

Posted by Veruska @veriska, Mar 7, 2017

I received the results from my bone test and they have recommended I start Prolia. I have read the side effects and I am concerned. Has anyone use this drug and if so what side effects have you experienced. Thank you

Unfortunately, none of the drugs available to those of us with osteoporosis are optimal.

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@mabel343

The only drug that actually builds new bone is Forteo, which is a daily injection. There is a new drug just coming on the market, but I don't know anything about it. If you experience side effects with Forteo you can just stop, where Prolia is in your system for at least six months. As I understand the way Prolia works, it stops the natural breakdown of old bone, and suppresses the immune system to do so, allowing you to hold onto old bone that shows up on the dexa as increased bone density. I stopped Prolia after three injections, due both to the many side effects that greatly impacted my quality of life and learning the facts about how it works. There is the risk of rebound fractures when stopping Prolia. I did not go on a relay drug after my last Prolia injection in June of 2018, and have not experienced any fractures. I strongly advise doing your own research before starting any of these drugs. I caved to pressure and fear mongering and started Prolia without doing enough research myself.

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Mabel343… I so agree with you not to cave in to the pressure and start the shots & drugs…Yes do your research!!! Just visit Osteostrong
and see the scientific research done!. Also you can find locations nearest to you.

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@debbiem

A good thing to remember is that we rebuild our bones every 10 years (I've even read on some ortho sites that its every 7 years). And we continue to do that until we die….So….we just need to be conscious of what we're putting in our mouth that helps bone growth, what hinders it, be sure to stay hydrated, and exercise. As a bone doctor told me a few years ago when I was sent to him for a -3.4 score, it depends on heredity, diet, bone architecture, bone strength, etc not just on a DEXA score which actually doesn't measure TRUE density (mass per unit of volume), but measures AREA density (mass per unit of area). Plus, he told me that my bone loss was most likely due to all the prednisone I had been on for many years….which, if I got off of I could probably speed up bone growth fairly quickly.

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Some good points made to know and to remember….thank you.

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@mabel343

The only drug that actually builds new bone is Forteo, which is a daily injection. There is a new drug just coming on the market, but I don't know anything about it. If you experience side effects with Forteo you can just stop, where Prolia is in your system for at least six months. As I understand the way Prolia works, it stops the natural breakdown of old bone, and suppresses the immune system to do so, allowing you to hold onto old bone that shows up on the dexa as increased bone density. I stopped Prolia after three injections, due both to the many side effects that greatly impacted my quality of life and learning the facts about how it works. There is the risk of rebound fractures when stopping Prolia. I did not go on a relay drug after my last Prolia injection in June of 2018, and have not experienced any fractures. I strongly advise doing your own research before starting any of these drugs. I caved to pressure and fear mongering and started Prolia without doing enough research myself.

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Just remember that Forteo is a synthetic parathyroid hormone. Synthetic PTH can cause Alzheimers. It increases bone growth temporarily…but you will lose any benefits within 4 weeks of quitting it….that's why most doctors put patients on prolia or another drug after coming off Forteo. It causes erosion of the GI tract, can cause bone cancer (black box warning on the drug info sheet). Forteo also increases calcium in the blood which can actually weaken bone strength. It also decreases magnesium. 60% of magnesium is found in our bones. It also increases cortisol, which blocks calcium absorption and decreases bone cell growth. These stats are what helped me make the decision to NOT take it. Instead….I take boron, Vita D, Vita K2, omegas, Vita C, among other supplements, stay super hydrated with water, do OsteoStrong, and walk/take stairs every chance I get.

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@debbiem beginning to think that the risks of all these osteoporosis drugs outweigh the so-called benefits.
You're right. Originally my doctor wanted me on Forteo for 18mos followed by Prolia.
All this bone building that then has the potential to disappear it's like an illusion. And then almost all the drugs have the ability to also break your bones. It's very weird.

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@lexusgs300

JK, Look in to other Options for improve all reverse Osteoporosis without drugs!!! Look for Osteostrong center in your area they are getting some amazing results, I was in Osteopenia, in ten months I have reversed it!!!:-) Best you go only once a week for 10 minutes…

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@lexusgs300 Osteostrong sounds potentially interesting but there are none anywhere close to me. If there was one I would consider using it along with one of the drugs. I have two excellent endocrinologists and I trust them, along with a good friend who is a retired gynecologist who has his wife on Reclast, and my PCP, whose mother is on Reclast. I think for most people the drugs along with exercise and diet provide the best results. I have had a fracture and do not want a second one.
JK

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@contentandwell

@lexusgs300 Osteostrong sounds potentially interesting but there are none anywhere close to me. If there was one I would consider using it along with one of the drugs. I have two excellent endocrinologists and I trust them, along with a good friend who is a retired gynecologist who has his wife on Reclast, and my PCP, whose mother is on Reclast. I think for most people the drugs along with exercise and diet provide the best results. I have had a fracture and do not want a second one.
JK

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@contentandwell It makes me feel a little better to see these comments about Reclast as I may be getting an infusion in the summer.

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@sue225

@contentandwell It makes me feel a little better to see these comments about Reclast as I may be getting an infusion in the summer.

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@sue225 I am waiting until I am beyond an MRI I have to have in April for something else. If all goes well with that I will do Reclast. The problems with it are far fewer than the potential of a broken bone, but even so, it is unnerving knowing it can cause other problems. Almost every drug can cause other problems too though. For instance, the darned prednisone I have to take has caused osteoporosis. Am I nervous about it? Of course.
JK

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I've just joined and appreciate reading through some of these posts. A few people have indicated they have decided to stop taking any meds. That's what I'm planning to do. I'm glad to hear there are others! I'm stopping fosamax. (I have only taken it for a few months.) I've done more reading about how it affects bones. Some of you have mentioned these issues. I have celiac disease, dx 15 years ago, that's why I have the osteoporosis. I exercise 5x a week and beginning to finally do strength training. I take calcium, magnesium and Vitamin D3. When I first saw my doctor to decide what I should take she told me, 'the most important thing is to see that you don't fall, more important than taking the medicine'. I take that to be aware, keep up with exercise, work on balance, etc.

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@joy4trees

I've just joined and appreciate reading through some of these posts. A few people have indicated they have decided to stop taking any meds. That's what I'm planning to do. I'm glad to hear there are others! I'm stopping fosamax. (I have only taken it for a few months.) I've done more reading about how it affects bones. Some of you have mentioned these issues. I have celiac disease, dx 15 years ago, that's why I have the osteoporosis. I exercise 5x a week and beginning to finally do strength training. I take calcium, magnesium and Vitamin D3. When I first saw my doctor to decide what I should take she told me, 'the most important thing is to see that you don't fall, more important than taking the medicine'. I take that to be aware, keep up with exercise, work on balance, etc.

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Welcome @joy4trees, to Connect and to this timely, complex and important discussion of bones and how they need some help as they grow old with us. Our mission is to improve the quality of all of our members' lives. Since you have been reading posts on this issue, do you have a sense of what all of your options are and where they might fall on a risk analysis chart?

Your plan is to avoid medication. If that is your choice may I introduce you to my friend Debra Rose, the author of "Fallproof". You can find the book on Amazon. Debra is a professor of kinesiology and a noted trainer of physical therapists in how to help us learn how not to fall. ( She actually is a friend.)

And I remember that the surgeon who performed my reverse shoulder replacement told me as I walked out the door….."don't fall, Chris, I can't fix you."

Please let us know of findings and thoughts that might help others.
Be safe and protected.
Chris

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@artscaping

Welcome @joy4trees, to Connect and to this timely, complex and important discussion of bones and how they need some help as they grow old with us. Our mission is to improve the quality of all of our members' lives. Since you have been reading posts on this issue, do you have a sense of what all of your options are and where they might fall on a risk analysis chart?

Your plan is to avoid medication. If that is your choice may I introduce you to my friend Debra Rose, the author of "Fallproof". You can find the book on Amazon. Debra is a professor of kinesiology and a noted trainer of physical therapists in how to help us learn how not to fall. ( She actually is a friend.)

And I remember that the surgeon who performed my reverse shoulder replacement told me as I walked out the door….."don't fall, Chris, I can't fix you."

Please let us know of findings and thoughts that might help others.
Be safe and protected.
Chris

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Thanks, I've not heard of 'Fallproof'. Sounds like a good resource.

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