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Prednisone Side Effects

Posted by Anonymous-aeaf6ea1 in Men's Health, Oct 23, 2011

I live with someone that takes this medication and he is like Jekyll and Hyde sometimes. People have told me that this medication can make people act like that. Anyone else have experience taking prednisone long term? I don't know if I can handle living with him for the rest of my life. He gets verbally abusive when he gets angry and he can blow a fuse at any time. There is no way to know when he is going to get ticked off about something. He is very difficult to live with and the abuse has taken its toll on me.

Tags: mens health, mental health, womens health, Other, medicines


Posted by @debera, Oct 27, 2011

Prednisone is not something a person wants to stay on for a long time as I think it can harm the liver long term and yes it can make you mean. Why is he on the prednisone?


Posted by @nativefloridian, Oct 27, 2011

He has been on and off prednisone for the past ten years. Unfortunately, he now believes he should remain on it for the rest of his life. He is not well, mentally or physically and the only good thing the prednisone does is keep his joints from hurting so much now. He was diagnosed with ulcerative colitis about 15 years ago and the only medicine that seemed to help since then has been prednisone. He has already had cataract surgery at the age of 41, had his colon removed completely and has osteoporosis.


Posted by @debera, Oct 28, 2011

I am sorry to hear this. God Bless and I will pray.


Posted by @nativefloridian, Oct 29, 2011

thanks for the prayers, they are much needed as he is very sick, mentally, emotionally and physically now. There is not much i can do anymore, except leave him alone or he rages at me. I have had enough and I will do my best to have compassion for his illness. That is best and if he chooses to stay on this medication he will probably suffer more side effects, there is simply nothing more to do other than watch him go to specialist after specialist for the rest of his life. He sees a neurologist, gastroenterologist, general practitioner, colon & rectal surgeon, orthopedic group and any other doctor that he thinks will be beneficial. I think if he were to take the energy he expends seeing all of these specialists so often that he could be in much better physical shape if he just exercised a bit and ate right. He refuses to eat half the time when he is in one of his mood swings. Sad, but true, he probably makes himself feel terrible with the way he treats his own body. he won't listen either, every time anyone makes a suggestion to him to gain weight or exercise he just blows them off and says he doesn't need to. He thinks people are demanding when they are just suggesting better more healthy ways for him to live. His rational thinking has gone out the window when it comes to his health. .

JanWhitebear likes this

Posted by @jcallison, Oct 29, 2011

Native Floridian,
You are in a very difficult situation, but I don't think that it is being caused by Prednisone.

This fellow is angry about feeling ill, and would most likely rage with or without Prednisone. Is he REALLY ill, or is he a hypochondriac?

And are you sure you are not supplying the masochistic component to his supplying the sadistic component in a sadomasochistic relationship?



Posted by @nativefloridian, Oct 31, 2011

Whew, now that's something to look into! I'll do the research and get back to ya! Thanks.


Posted by @jcallison, Oct 31, 2011

Hey NF,

Hearing that this fellow has been having health problems for fifteen years and has been taking Prednisone on and off for ten of those fifteen years, and that he has become a person who is ready to rage at the drop of a hat, along with your having stood by him through all of this, is an indication that even though the situation is obviously extremely difficult and stressful, there must be something that keeps you from breaking out of the situation.

Am not sure if you are familiar with "game theory", but the book "The Games People Play" by Eric Berne is a wonderfully insightful book on the mechanics of human relationships, and how to deal with difficult situations such as the one you describe.

Might I add that mood swings such as is exhibited in bi-polar (manic/depressive) behavior is another indication that one is unhappy about something, in this case, it is apparently his ill health.

Depression is "passive anger" and mania is "agressive anger". Manic/depressive behavior is oft times the way the bi-polar person "controls" those around them.

You wrote: "I think... that he could be in much better physical shape if he just exercised a bit and ate right. He refuses to eat half the time when he is in one of his mood swings."

If he ate better and exercised, he would be in better physical shape. If he was in better physical shape, he wouldn't be able to rage about his illness. If he were not able to rage at those around him, the wouldn't have as much control over them. So perhaps he is using his illness as a tool to maintain domination. This is a strategy used by the basically insecure person. And one would think that all one had to do was make this person feel secure, and everything would be alright. Alas, showing a person that they have no need to be insecure only reinforces the efficacy of their strategy.

As was said previously, you are in a very difficult situation.

BTW, sadomasochistic relationship can be quite rewarding and satisfying if the game players know what they are doing. For a very insightful example, the movie "Who's Afraid of Virginia Wolfe" with Liz Taylor and Richard Burton is quite a nice romp thorough the mechanics of a sadomasochistic relationship. Alas, few people who are in that kind of relationship recognize it as such. They think it is "real", which is another reason to come to understand "game theory".

There are, BTW, quite a few books along with "The Games People Play" on "game theory", such as "Finite and Infinite Games" by James P. Carse, and "The Master Game" by Robert S. DeRopp.

Also if you will Google "Game Theory" you will find, the whole world is viewed by those running the world as a huge game, with "actors", its own language, and an entire set of very specific rules.

Anyway, NF, will await with abated breath that which you find in your research.

Take excellent care, and here's hoping you are well.


Native Floridian likes this

Posted by @nativefloridian, Nov 1, 2011


I don't think I am supplying any part of a sadomasochistic relationship. That doesn't mean this person isn't self defeating. Lately, I have taken a step back and am looking at my life much differently. Professionals tend to agree with you, insecurity is the root problem. Unfortunately, I can not change someone else's insecurities, only mine. What he has been through in the past few years causes him to be more insecure. Alot of us are insecure in many ways and it is just part of human nature.

I am well and glad so many comments were made here. I am sorry that you don't believe that prednisone taken long term can have bad affects. Maybe the combination of drugs you are on keeps that from taking place? I just know that this man has only taken that one drug and refuses to take anything else. He won't even take an aspirin, tylenol, or advil. He is a tough nut to crack, very set in his ways, and yes, he comes from a long line of hypochondriacs which basically drive me crazy talking about all of their ailments every time I see them! That does not mean he has not had his share of true medical conditions, but it does mean that he has cried wolf one too many times. I get my facts straight from his doctors now and make my own conclusions from test results. No more discussions with a hypochondriac.

I'll be doing some reading and movie watching soon, thanks for the titles!


Posted by @eskimo, Aug 2, 2012

I take 60 mg/day of prednisone for an optic neuritis, and for a month now since taking it have only felt very happy and highly energetic. I have felt some hunger, but I've been able to control it with snacking on fruits. I also take a mood stabilizer and I'm not certain if this is the reason why I'm not feeling the strange irritable mood swings like others here have stated. I am pretty sure the mood stabilizer is controlling the mood swings. Maybe this could be helpful to others as something they could discuss with their doctors and experiment with. I was able to get sufficient hours of sleep, but my body is hardwired to wake up like 5 am each day probably because I'm a morning person.


Posted by @nativefloridian, Aug 17, 2012

Sounds like the mood stabilizer is a good thing. Thank goodness my husband finally has stopped taking the prednisone. It gave him cataracts after he took it for a long time (10 years). Hope you don't have to stay on it too long.


Posted by @jcallison, Oct 29, 2011

Hey Debera,
Prednisone does NOT harm the liver long term. And it has not made ME mean.



Posted by @charte1983, Aug 1, 2013

Using prednisode long term does have an affect on the liver. Fatty liver.

JanWhitebear likes this

Posted by @bettyann, Oct 29, 2011

Several months ago I had cataract surgery and was given Prednizolone eye drops right before and for a few weeks after the surgeries. They literally made me sick to my stomach. I finally found a doctor who agreed with me. I finally found a way to take them so they would not run down my sinuses and into my stomach. Prednizone of any kind can be an awesome drug...and a horrid drug. I so hope someone will listen to you so that you can get him switched to another drug. Another solution DOES exist. Best wishes to you.


Posted by @klcreations, Nov 2, 2011

My father was on & off prednisone for years. We called his prednisone personality predno boy. IT WAS AWFUL! He was rude, sarcastic & short. It was very difficult to be around him & more difficult to try to be supportive. Nothing was good enough & nothing was right. He hated the way that it made him feel & that was part of the reason that he acted out but I back you 100% in believing that prednisone causes mood swings & angry outbursts - not to mention a definate personality change. Sorry I don't have anything more helpful but thought I would let you know that my (and my family's) experience was the same as yours.


Posted by @nativefloridian, Nov 2, 2011

Thanks for your post. It is a roller coaster ride, he is up and down....i am even keel since starting marriage counseling with predman. It is better mostly.

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Posted by @klcreations, Nov 2, 2011

Yay! Glad to hear you are on the up & up. Sounds like you are in a tough situation. Hope things continue to get better!

Native Floridian likes this

Posted by @nativefloridian, Nov 3, 2011

Yay is right! He is going out to watch football with some friends Sat. night and seems happy about it. Sigh, what a relief to see him smile a little. Hopefully, his friends will realize how much he needs them in his life. Had a long talk with one of them when he called with the invite and I feel much better just knowing he will be with some other people besides me and the kids this weekend. Say a prayer for the weekend to go well (for a change). It is time for a real breakthrough for this guy. A woman can only take so much grief from one man!

Fibro-sufferer likes this

Posted by @peacekeeper, Nov 14, 2011

This has been removed for violation of our terms of use.


Posted by @nativefloridian, Nov 16, 2011

Peace Keeper, I understand your philosophy but there are people that truly need this Master Physician to work through human physicians in order to heal them. I don't think that discouraging others to seek medical attention is a productive thing to do on this forum. Not everyone on this earth gets a miraculous healing like you. I am not discounting your experience and believe your experience is your reality. Please realize this and know that although everyone's opinion is respected here many have been helped by medical doctors. I am happy for you and happy to hear you are enjoying life again. Blessings!


Posted by @marigold, Nov 24, 2011

Native Floridian- that was well stated and I couldn't have said it better. Thank you for your comments to Peace Keeper


Posted by @fibrosufferer, Nov 22, 2011

Peace Keeper- Is that what you do?? Preach?? This is about reaching out for Help from our peers...its not
I've read a ton of discussions and most of them have a comment made by you talking about god...well let me tell you something....not everyone believes in god...especially when we are in such disparity of being alone in our illnesses..I personally do believe in our savior, Jesus, but not everyone does and frankly I'm tired of seeing your comment about it on EVERY discussion!!


Posted by @ckellis, Dec 20, 2011

I was on 100mg a day off and on for 8 years. My husband is a Saint, to have stayed with me. I did just what you are saying, mean is a nice way of putting it.
It IS the medication!! Not him, he cannot help it. However, we do not have a choice sometimes. I found that taking a Bach remedy helped a lot. I took "impatiens" a few drops in my drinking water took off most of the explosive edge. all natural over the counter, but make sure you share what he is doing with his Dr. You can get past all of this!


Posted by @nativefloridian, Dec 21, 2011

We have since separated because he is noncompliant with his surgeon. He has gone to another physician to get prednisone again, against his surgeon's advice. This man is addicted to prednisone and unfortunately, a very miserable person to live with. I am much happier since he has moved out. My depression has lifted and life is good again. He is still miserable, just that now he is alone and not making me miserable also.


Posted by @ckellis, Dec 21, 2011

Understood. All the best to you!

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