Shifting from Prednisone to Hydroxychloroquine

Posted by charlena @charlena, Jan 22, 2020

My husband is now completely off prednisone. He transitioned from the prednisone to hydroxychloroquine. Has anyone else transitioned from the prednisone to the hydroxychloroquine? I would like to hear results of other people doing this. Thank you!

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I’ve been taking hydroxychloroquine for 17 years and never had any reactions. I’m wondering if the dose is too strong. I also have PMR and the hydroxy did nothing for that pain. I’m on prednisone in addition to hydroxy.

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@reets70

I’ve been taking hydroxychloroquine for 17 years and never had any reactions. I’m wondering if the dose is too strong. I also have PMR and the hydroxy did nothing for that pain. I’m on prednisone in addition to hydroxy.

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My rheumy put me on Hydroxychloroquine with the Prednisone straight away and I've been taking it for three years now. I think it somehow helps with the Prednisone . However, I'm now down to 1 mg. Prednisone and hope to be off it by mid August.

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@ncgal

My rheumy put me on Hydroxychloroquine with the Prednisone straight away and I've been taking it for three years now. I think it somehow helps with the Prednisone . However, I'm now down to 1 mg. Prednisone and hope to be off it by mid August.

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Sounds like the combination worked for you - great! I think the result really varies person to person. My rheumy added hydroxychloroquine to my treatment with prednisone about 8 months into my first year of PMR. I had an immediate massive flare up and that was the end of that. I'm at 6+ years of PMR now but am down to 1.5 mg of prednisone and holding. I'm sure that part of the reason I've been on pred so long is because I have continued to work throughout my treatment. That makes it tougher to try any kind of faster reduction with prednisone. Patience has been required lol.

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@raven1955

Sounds like the combination worked for you - great! I think the result really varies person to person. My rheumy added hydroxychloroquine to my treatment with prednisone about 8 months into my first year of PMR. I had an immediate massive flare up and that was the end of that. I'm at 6+ years of PMR now but am down to 1.5 mg of prednisone and holding. I'm sure that part of the reason I've been on pred so long is because I have continued to work throughout my treatment. That makes it tougher to try any kind of faster reduction with prednisone. Patience has been required lol.

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That's a lot of years. Good luck with getting off Prednisone.

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I have had PMR for 30 years. Been on and off prednisone (P) for much of that time. Most recently I was on 5 mg P daily and Aleve 220 mg twice a day. Had to go off Aleve and went to 7.5 mg P. It didn't do the trick so went on 10 mg P. Now I am back on 7.5 P and hydroxychloroquine 200 mg twice a day. It seems to be working. I will reduce my P to 5 mg per day in a couple of weeks. I am surprised how well hydroxychloroquine is working. I will keep you posted. Will see my rheumatologist in August.

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@angelique407

Hello,
I'm curious if this medication Plaquenil aka Hydroxychloroquine has helped anyone?

I'm not tolerating prednisone at all. Took prednisone about 8 months of 5-10 mg when the side effects hit, by constant all over body cramps.
Weaning off the prednisone brought to light that I apparently have PMR. Already diagnosed with CREST scleroderma. 2 mg I was extremely fatigued and in pain. 1 mg was worse. Cramps nearly gone at that time. Couldn't take the fatigue and pain. Back up to 5 mg. Back to cramps again. Let me add I am on magnesium and potassium daily with hopes it was relieve cramps.

My Rheumatologist wants to put me on Hydroxychloroquine to replace prednisone. I've never had a normal sed rate in nearly 2 yrs. Always 55-105.

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I just started hydroxychloroquine for my Erosive osteoarthritis of the hands. No side affects yet. Been prolonging taking it but in order for hands to slow down because they are a progressive EOA. Figured I give it a shot. Not a fan of any type of meds. But....

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