Starting pemetrexed and carboplatin pembrolizumab: What to expect?
Hello, My husband is due to start his first treatment of pemetrexed and carboplatin pembrolizumab. I was wondering the side effects and anything that I can do to help lesson.
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I'm on the third day after my infusion now. The first two have been easy with my only side effect being fatigue, so I've been resting and sleeping more than I usually do, which I actually like, as I normally can't take naps. I'm feeling a little more nauseous today but trying to stay ahead of it with the anti-emetics they prescribed for me. Also starting to notice the taste of foods and drink - especially coffee - are starting to dull. The strange thing is that I had radiation pneumonitis in March and since the prednisone treatment finished I've been waking up in the mornings wheezing a little and coughing when I get up and walk around until my lungs clear. They've told me I have some slight COPD so I've attributed it to that. As of yesterday, I'm waking up with totally clear lungs. It's highly doubtful that it's the alimta and carbo somehow working this soon, but whatever is causing it I'll take it. I have no idea what to expect this week re: further side effects, will keep you posted if you'd like. I keep reading it tends to hit people harder on the 3rd and 4th days, I'll see what happens.
@professorc HiYa it’s Dave from Pa: I also went 1 yr before they confirmed my previously treated lung cancer had metastasis. We started the same chemo your husband is scheduled for as well as (5) rounds of radiation in July. My latest scan showed (8) of (10) tumors have shrunk or disappeared! We’re maintaining the KEYTRUDA immunotherapy every 6 weeks for now. Yes, the first few days following treatment can be a bit rough but with results like these I’ll tolerate it. Hang in there you’re on the right path. DgA
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Thank you so much. This was very helpful. He gets his first chemo treatment on Monday. I’ll let you know how he’s doing. I was also wondering if you do any protein buildup prior to treatment. If so, can you share what you do? I have a Fussy eater here!
@dougmck
Hi,
My husband starts his first chemotherapy on Monday. I hope he’s not real sick from it. Seems like these oncologists now have medication to help everyone with harsh side effects. That’s a big Blessing.
Have you changed your diet at all since your cancer diagnosis?
ProfessorC
Keeping in mind this is my first infusion and they supposedly become cumulatively a little more difficult, I'm still doing ok so far on my fifth day. I've taken the anti-nausea drugs they gave me every six hours and haven't experienced any nausea at all. Today I'm going to go without them altogether and see if I still need them. The fatigue also seems to be gone as of yesterday. Re: diet, I'm eating a little differently because as I mentioned earlier foods are losing their flavor. I've been eating more yoghurt, ice cream, some soups. I've been juicing vegetables and fruit for the last couple of weeks, but have slacked off for the last couple of days and need to get back into the practice of doing it again. Let me know how your husband is doing. From all that I'm reading, it seems like most people can handle these chemo drugs pretty well. In 2008 I was treated with six cycles of cisplatin and taxotere for a lung mass and felt like I had been hit by a truck compared to this regimen. I just hope it's working...