Ovarian cancer - not responding to chemo

Posted by ktoth @ktoth, Jul 27 1:03pm

I have high grade serous carcinoma ovarian cancer. I have a 12cm tumor on my left ovary, the cancer has spread to two lymph nodes and also both of my lungs. I have had 4 rounds of paclitaxel and carboplatin. A CT scan was done post round 3 of chemo. The results show that the chemo is not working. The cancer lesions in my lungs have grown. The surgical oncologist said that I am currently not a candidate for surgery as the benefit doesn't outweigh the risk. We meet with the medical oncologist this Friday, July 31, 2026.

What other options are out there for me at this point since my cancer is platin resistant and that is typically the gold standard for treating ovarian cancer.

Does the Mayo clinic have more advanced options for someone like me in my current situation? I live in British Columbia Canada. Debating if I should seek treatment abroad where more advanced care would potentially be available for me.

I feel like I have just lost 3 precious months undergoing a chemotherapy that wasn’t working.

Interested in more discussions like this? Go to the Gynecologic Cancers Support Group.

maghera | @maghera | 2 days ago

In reply to @naturegirl5 "@maghera Approved in Canada but not paid for by your province (British Columbia)?" + (show)

@I wonder how we can change that. I believe the cost is out of reach for most people.

I did sign the form asking our premier to try and make this happen.

maghera | @maghera | 2 days ago

In reply to @naturegirl5 "@maghera Approved in Canada but not paid for by your province (British Columbia)?" + (show)

@naturegirl5 thank you for this. I am going to start a new round of Chemo and this drug may be suggested.
Affording it would be difficult.

cookercooker | @cookercooker | 1 day ago

Approved for endometrial cancer? I'll follow that up, not that I can afford to pay for it.

cookercooker | @cookercooker | 1 day ago

In reply to @maghera "@I wonder how we can change that. I believe the cost is out of reach for..." + (show)

@maghera
I missed that. What form?

maghera | @maghera | 1 day ago

In reply to @ktoth "@maghera they have stopped the current treatment as my CT scan that was done on July..." + (show)

@ktoth
My chemo did not work for at least 4 rounds.

maghera | @maghera | 1 day ago

In reply to @cookercooker "@maghera I missed that. What form?" + (show)

@cookercooker

it was snt out by the drug company.

cookercooker | @cookercooker | 1 day ago

In reply to @maghera "@cookercooker it was snt out by the drug company." + (show)

Oh. I didn't get that. As far as the info on the web goes, it isn't approved for gynecological cancer in Canada — yet. But there are exceptions.
And, did you see this? https://recherche-essais-cliniques.canada.ca/en/clinical-trial/300790-endometrial-cancer

Helen, Volunteer Mentor | @naturegirl5 | 1 day ago

In reply to @cookercooker "Oh. I didn't get that. As far as the info on the web goes, it isn't..." + (show)

@cookercooker Thank you for adding the clinical trials link for Canada.

cookercooker | @cookercooker | 1 day ago

In reply to @naturegirl5 "@cookercooker Thank you for adding the clinical trials link for Canada." + (show)

@naturegirl5 you're welcome. I hope they're still recruiting and somewhere in BC. There is likelt site that has the locations, but I haven't found it yet.

keirahaley | @keirahaley | 1 hour ago

My friend is having great success (has tried many other treatments) with the GSK trial - you can call them and see If you can get in - there is a BC sector and there are numbers you can call. I was holding on to this option for myself if needed - I have low grade which is slow growing but difficult to find efficient treatments. This trial has boasted a 60% positive response. Worth a shot. Here is a link https://www.google.com/search

Sending tonnes of love to You!!!