Orgovyx extreme fatigue side effects

Animals are a good source of exercise too, keeps ya busy feeding and cleaning the litter box

I've been getting a lot of leg cramps I attribute to Orgovyx but not general stiffness.

I’m 70 with stage 2 and will start radiation in a few weeks. I’ve been on Orgovyx for 2 months. I took it around 8 am the first month and experienced the same fatigue but switched to taking it around 7 pm which seems to have helped my days feel better. No sleep problems noticed so far other than the usual trips to the bathroom.
Getting daily varied exercise even when you don’t feel up to it also helps. I’m very fortunate to have a beautiful new YMCA. gym and indoor lap pool 5 minutes from my home. I always say that the hardest part of my old man workout is talking myself into driving there and always feel better afterwards.

Funny you mention leg cramps. I too was getting leg cramps and I had a theory that the hot flashes/sweating was depleting my electrolytes and causing dehydration. Dehydration can cause leg cramps. So, I have been drinking fluids like Gatorade and the leg cramps have diminished significantly. This doesn't validate my theory, but, it seems to make sense.

@markslice7, you mention muscle stiffness. I found a couple of related discussions that may help:
- Severe stiffness in fingers after starting Eligard.
https://connect.mayoclinic.org/discussion/severe-stiffness-if-fingers-after-starting-eligard/
- Orgovyx and Zytiga combined
https://connect.mayoclinic.org/discussion/orgovyx-and-zytiga-combined/
Can you describe the muscle stiffness? Is it painful, weak, or just hard to get moving? Is the stiffness in a particular muscle group like legs or fingers? Has it gotten better since you first posted?

What kind of proteins? Whey supplement? Vega Sport? Or whcih foods?

I'm 88 and 150lbs, too. ave you added muscle?

Thank you so much for your experience, I am definitely going to alter and try that based on your experience. I do not suffer debilitating fatigue but some, so any decrease would be welcome.

just started with ORGOVYX ( 1 month) - so yes I have the hot flashes ( no too bad but noticeable), fatigue , cant sleep at times, it has made me feel jittery/anxious, loss of appetite at times..and generally made my life much less than what it was...what a torturous rememdy for us guys with PC.

I viewed it as a new me kind of thing. Orgovyx knocked me down some, added to my already sleep issues but didn't stop me from doing anything. Exercise really helped and the focus was doing the push away to get exercising and it always helped me feel better.