My bone markers would seem to show no effect on Evenity, but I just did two years of Tymlos. So sorry that you did 12 months with no results. I hope it at least prevented further loss.
@ingridbergman so it kept you from losing but didn't give you any gains. What will you do next? Do you think Evenity helped with bone quality if not density? I wonder what your doctor has to say on this.
i had full dose reclast after evenity. the dexa was at the same facility, but not the same machine. the endocrinologist felt i had the evenity too close to my last reclast with only a year between my previous reclast and the evenity. she thought that was the reason.
Hi @ingridbergman - Following Reclast with Evenity will reduce the results for sure, but you still should have seem some benefit. Attached is a chart that shows some trial data.
My primary care doctor has not had good luck with Evenity and I'm not sure why. I also had poor results, but I contribute it to my hypercalciuria. You can't make bone if you are losing calcium faster than you can absorb it from your diet. Have you checked your 24 hour urine calcium? Also, you might want to get your 1,25(OH)2D measured just in case something whacky is going on there. Get your phosphorus checked as well. Disorders of low serum phosphorus can also be an issue. A few things for you to check out.
Hi @ingridbergman - Following Reclast with Evenity will reduce the results for sure, but you still should have seem some benefit. Attached is a chart that shows some trial data.
My primary care doctor has not had good luck with Evenity and I'm not sure why. I also had poor results, but I contribute it to my hypercalciuria. You can't make bone if you are losing calcium faster than you can absorb it from your diet. Have you checked your 24 hour urine calcium? Also, you might want to get your 1,25(OH)2D measured just in case something whacky is going on there. Get your phosphorus checked as well. Disorders of low serum phosphorus can also be an issue. A few things for you to check out.
I just finished my year of Evenity. My spine scores improved significantly (-1.9 from -2.9), however my hips not much improvement. Total hip (-2.6 from -2.5) and femoral neck (-1.8 from -1.9). My CTX marker was 514 before treatment, dipped down to 143 mid way and landed at 201. Still waiting for the PINP results however it was decreasing throughout the Evenity treatment.
I have read that Evenity works best on the spine. I am weighing my options for next steps which I am told to start immediately to lock in gains. . My doc recommends 3 - 4 shots of Prolia followed by a Reclast infusion or straight to Reclast. The Prolia would hopefully extend some of the benefits of the Evenity. I guess my hope of taking a drug holiday will not happen for a while.
Does anyone have any sequencing protocols to share?
I just finished my year of Evenity. My spine scores improved significantly (-1.9 from -2.9), however my hips not much improvement. Total hip (-2.6 from -2.5) and femoral neck (-1.8 from -1.9). My CTX marker was 514 before treatment, dipped down to 143 mid way and landed at 201. Still waiting for the PINP results however it was decreasing throughout the Evenity treatment.
I have read that Evenity works best on the spine. I am weighing my options for next steps which I am told to start immediately to lock in gains. . My doc recommends 3 - 4 shots of Prolia followed by a Reclast infusion or straight to Reclast. The Prolia would hopefully extend some of the benefits of the Evenity. I guess my hope of taking a drug holiday will not happen for a while.
Does anyone have any sequencing protocols to share?
Connect
Connect
Like
Helpful
Hug
My bone markers would seem to show no effect on Evenity, but I just did two years of Tymlos. So sorry that you did 12 months with no results. I hope it at least prevented further loss.
thank you for your reply.
my dexa scan showed no improvement or loss with evenity. i did not have bone markers.
@ingridbergman so it kept you from losing but didn't give you any gains. What will you do next? Do you think Evenity helped with bone quality if not density? I wonder what your doctor has to say on this.
Curious, were you on a drug prior to Evenity? Did you use the same facility for DEXA? Really sorry to hear this yet glad you didn't lose.
-
Like -
Helpful -
Hug
2 Reactionsi had full dose reclast after evenity. the dexa was at the same facility, but not the same machine. the endocrinologist felt i had the evenity too close to my last reclast with only a year between my previous reclast and the evenity. she thought that was the reason.
-
Like -
Helpful -
Hug
1 ReactionHi @ingridbergman - Following Reclast with Evenity will reduce the results for sure, but you still should have seem some benefit. Attached is a chart that shows some trial data.
My primary care doctor has not had good luck with Evenity and I'm not sure why. I also had poor results, but I contribute it to my hypercalciuria. You can't make bone if you are losing calcium faster than you can absorb it from your diet. Have you checked your 24 hour urine calcium? Also, you might want to get your 1,25(OH)2D measured just in case something whacky is going on there. Get your phosphorus checked as well. Disorders of low serum phosphorus can also be an issue. A few things for you to check out.
-
Like -
Helpful -
Hug
5 Reactionsthank you. i will check these tests out.
my serum calcium has always been normal.
I just finished my year of Evenity. My spine scores improved significantly (-1.9 from -2.9), however my hips not much improvement. Total hip (-2.6 from -2.5) and femoral neck (-1.8 from -1.9). My CTX marker was 514 before treatment, dipped down to 143 mid way and landed at 201. Still waiting for the PINP results however it was decreasing throughout the Evenity treatment.
I have read that Evenity works best on the spine. I am weighing my options for next steps which I am told to start immediately to lock in gains. . My doc recommends 3 - 4 shots of Prolia followed by a Reclast infusion or straight to Reclast. The Prolia would hopefully extend some of the benefits of the Evenity. I guess my hope of taking a drug holiday will not happen for a while.
Does anyone have any sequencing protocols to share?
What was your experience during your Evenity treatment, any side effects to mention? Thanks.