New to kappa light chain testing

Posted by rosemary73 @rosemary73, May 4, 2024

Hi! I am new to this free light chain results as I had blood work done last August by a hematologist. I had high Kappa free light chain of 26.0 but the other two tests lambda and ratio were normal. The hematologist said my tests that she tested me for were normal. After experiencing some health issues lately I did my own research and discovered my light chain results myself as my red blood count stays somewhat low. I informed my PCP of my find and she referred me to a cancer specialist. On his first findings my Kappa light chain has gone down to 22.2 and the other two tests were normal. I'm new at this and am scared to death that it could be Cancer etc. Can anyone that has had experience with this inform me a little more. I do have another appointment scheduled with my Cancer doctor. I haven't been diagnosed with anything yet but am so scared of a cancer diagnosis..

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Profile picture for kjoed53 @kjoed53

@barbarian1
Claude is an AI app. It's free. I use it to understand my blood work prior to my rheumatologist or hematologist/oncologist visits. I also used it to explain my PET scan results. I like knowing what to expect and what to ask at each visit. It helps me to process what I hear faster so I'm not dwelling on one point and missing the next.

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@kjoed53 oh yes I use AI ChatGPT for many subjects one being cancer and also legal issue they are great source. Like having free non court atty

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Profile picture for cousinvinney @cousinvinney

@barbarian1
Did my bone marrow and fat biopsy in March at the Mayo Clinic without sedation .. local only..no problem what so ever.
No worries

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@cousinvinney loved that movie and Joe Pesci one of my fav actors & the girl actress Marisa Tomei so hot❤️❤️

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My hematologist/oncologist said he was more concerned with the ratio than the free Kappa Lt chains by itself.

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Profile picture for kayabbott @kayabbott

@barbarian1 and @cousinvinney, elevated ImmunoGlobulinM antibodies indicate infection, inflammation, and/or various blood disorders (normal is around 40-250). M spike is different than IGM; it is a measure of monoclonal antibodies in the blood. As in the case of an M spike (0.1 to 0.4 g/dL is detection limit so if yours is 0.056 g/dl it is OK) results need to be evaluated by the oncologist because individual numbers can have multiple causes. https://my.clevelandclinic.org/health/body/igm This link is for MM, but it does explain various blood and other test results and normal ranges: chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://themmrf.org/wp-content/uploads/2023/07/Learn-Your-Labs_patient-toolkit.pdf

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@kayabbott
Yes my M spike results were interrogated at the Mayo Rochester with Bone marrow sampling. They did find plasma cells however. too low for diagnosis purposes. Therefore they ruled out MM but I did earn the MGUS classification. Now it's just a watch, verify, a wait and see issue.

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Profile picture for cousinvinney @cousinvinney

@kayabbott
Yes my M spike results were interrogated at the Mayo Rochester with Bone marrow sampling. They did find plasma cells however. too low for diagnosis purposes. Therefore they ruled out MM but I did earn the MGUS classification. Now it's just a watch, verify, a wait and see issue.

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@cousinvinney Hopefully it continues as MGUS and never turns into SMM or MM. That is the case with most MGUS.

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Please breathe. I tend to over-think my health. I was diagnosed earlier this year and thought I would lose my mind. Then I woke up the next day, and the next....
Dr visits still induce stress, but I am still here. So will you. Breathe.

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