Anyone know about daridorexant (Quviviq) for insomnia?

Posted by chuckiepoo1 @chuckiepoo1, Oct 25, 2022

I just very recently read about a new insomnia sleep medication by the company Idorsia. It is QUVIVIQ( daridorexant). I asked my PCP about it and he had not heard of it but did find it through his resources. Has anyone had any experience with this new drug? Also wondering, since it is new or relatively new whether most insurances will pay for it.

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Profile picture for Colleen Young, Connect Director @colleenyoung

@netter9064, I moved your query about daridorexant (Quviviq) for insomnia to this existing discussion:

- Anyone know about daridorexant (Quviviq) for insomnia? https://connect.mayoclinic.org/discussion/new-insomniasleep-medication/

I did this to bring everyone talking about this medication and insomnia into one discussion like @chuckiepoo1 @cmd @sleepy40 @ripley @lauralouisenelson @rocketjs @timbrownfl

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It's a game changer!

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Profile picture for sodog1989 @sodog1989

I tried it for the first time last night. I cant recommend it.
It did not make me sleepy. It did for some reason make a song play over and over in my head. I thought maybe I took too low of a dose and after 3 hours awake I took one more. I finaly fell asleep after another hour. But it was fitful spasmatic sleep. I had a few panic filled dreams. And still the constant replaying of the same song. Has anyone else had a similar experience? I cant imagine this drug making it through trails based on my experience. I may try it again but it will not be on a work day.

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Give it a month to work.

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Profile picture for aethos @aethos

I tried it and didn’t like it. I felt sleepy but couldn’t get to sleep very well. It gave me a hangover the next day…gave it four try’s….

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Give it a month, the hang over goes away and it works better with time.

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I tried Quivivic last year, and had mixed results with it. The first night, it gave me the worst nightmare of my life. I woke up from it and for about a solid minute, couldn't determine if it was a dream or reality. I kept trying it, and it got better as I was able to tell myself "it's only a dream" if the dream was a bad one. But it did give me a sort of "out of body" experience too, like I was watching myself trying to sleep. It is expensive, but insurance covered most of it.

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Quvivcq works Great for me. My problem is I get up In the middle of the night Several times and I have a hard time falling back asleep. This drug is amazing, I now have no problem falling back asleep when I wake up in the middle of the night. I've had no issues with the drug. And now that I'm getting a good night's sleep every night. I feel my memory and cognitive abilities have increased significantly.. This thing is the Holy Grail Of sleep medication. It's still on patent, so it's expensive if you don't have insurance, but it's well worth it. For me It worked the first night I took it. I guess it just depends on the person. My suggestion is give it a try and stick with it.

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If you have insurance but the copay is higher than you want to pay, you may be eligible for copay assistance. This brought my payment through my insurance from $395/month to $25/month. Otherwise, the pharmacy hopefully has discount options available. Check out:

Copay assistance card:
https://www.quviviq.com/savings/
or
https://www.goodrx.com/go/homepage-lander-sem-7
or
https://www.singlecare.com/
or
whatever your pharmacy has to recommend

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Doxepin and Gabapentin

Anybody with experience taking doxepin and Gabapentin together?

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