I cycle M,W,F, about 28 – 38 mi. each day. It used to be over 50. The statin has kept my muscles sore for 10 yrs but, my cardiologist said,”the numbers are perfect”. When I checked on the Repatha site it was mostly about adding Repatha to an existing statin. Just trying to come back to comfortable exercise. Any experience or suggestions would be helpful. By the way on 4 July I quit the statin when there was trouble getting up to stand. After vacation of about 3 weeks I am riding much better. Other riders are commenting about how well I am even doing uphill. Obviously, I have to get back on something beside Cholestramine.