1. < MAC & Bronchiectasis

mucus menifests pattern?

Posted by @ling @wangling, 2 days ago

Hi everyone,
It seems to me that someday I produce much more mucus than normal, then the day after that, I produce much less mucus than normal. Does anyone have a similar experience?
My pulmonologist told me that when I have less mucus out, don't think that you are getting better. I think it is good to remember that. But the fact is someday I do produce much less mucus than normal, especially when I have much more the day before. How could that be possible, since our body continuously produces mucus? I think some environmental reason might cause producing more mucus than normal, but why less than normal I don't understand. When I have less mucus out, I get nervous about it. Your experience is much appreciated.
Ling

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jill6063 | @jill6063 | 14 hours ago

Hi friends -

I just had an appointment with Dr. Daley last week and he said Brensocatib would reduce inflammation and exacerbations and reduce the decline of lung function. He said it decreased exacerbations by 20%, which he said is "huge in the medical field" because not all infections are bacterial (and there is nothing we can do about the viral infections). He also said that this improvement was shown over 52 weeks, and that perhaps the longer it goes out the more effective it will be.

I know of Brensocatib and Arikayce - are there are drugs in trial that may be coming our way??

Thanks for any info!

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cyndanna | @cyndanna | 14 hours ago
In reply to @scoop "Sometimes we can have both neutrophilic and eosinophilic features. For example, my last sputum test showed..." + (show)
@scoop

Sometimes we can have both neutrophilic and eosinophilic features. For example, my last sputum test showed 4+ polys, which is a high level of neutrophils, suggesting neutrophilic inflammation. BUT, I also have an IgE over 600, suggesting eosinophilic inflammation. If we are willing to try brensocatib it seems like that's the only real way to see if it helps. Fingers crossed!

Jump to this post

Thank you, my eosinophils are typically high. This makes sense.

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lilianna | @lilianna | 14 hours ago
In reply to @scoop "Sometimes we can have both neutrophilic and eosinophilic features. For example, my last sputum test showed..." + (show)
@scoop

Sometimes we can have both neutrophilic and eosinophilic features. For example, my last sputum test showed 4+ polys, which is a high level of neutrophils, suggesting neutrophilic inflammation. BUT, I also have an IgE over 600, suggesting eosinophilic inflammation. If we are willing to try brensocatib it seems like that's the only real way to see if it helps. Fingers crossed!

Jump to this post

Scoop good morning. I read Your post And thought how often are yoyr IgE and neutrophils checked. And who does it- a PC or a pulmonologist. Thank you

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1 reply
scoop | @scoop | 12 hours ago
In reply to @lilianna "Scoop good morning. I read Your post And thought how often are yoyr IgE and neutrophils..." + (show)
@lilianna

Scoop good morning. I read Your post And thought how often are yoyr IgE and neutrophils checked. And who does it- a PC or a pulmonologist. Thank you

Jump to this post

Neutrophils are collected with a CBC and Differential ordered annually by PCP (or immunologist). IgE was ordered by pulmonary.

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1 reply
lilianna | @lilianna | 11 hours ago
In reply to @scoop "Neutrophils are collected with a CBC and Differential ordered annually by PCP (or immunologist). IgE was..." + (show)
@scoop

Neutrophils are collected with a CBC and Differential ordered annually by PCP (or immunologist). IgE was ordered by pulmonary.

Jump to this post

Thank you

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namd | @namd | 8 hours ago

Hi, I am exactly the same. No 2 days are the same. I do airway clearance twice daily - morning and evening. I get very nervous about it all. I get lots of coughing fits during the day but sometimes it is a dry cough. Weather affects me - cold, damp weather is not good. Humidity is even worse! It is such a difficult situation to deal with and the fatigue is awful too! Good luck

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