Metabolic therapy for cancer

Posted by birdman518 @birdman518, Jun 20, 2023

I have several posts here about my newly-diagnosed metastatic melanoma, but I wanted this to be a new thread.
I was looking for alternative therapies for cancer, and I was afraid that most of them would seem, well, a little kooky (sorry, but that's what I thought).
I found one, however, that seems to be both outside the mainstream standard-of-care, but yet very well represented in the scientific literature, including at least one Nobel Prize (Warburg), and that is the metabolic theory of cancer. It seems as though its primary promoter is Dr Thomas Seyfried of Boston College. He is a professor of biology, genetics, and biochemistry at Boston College.
He has many books, articles, and videos online, so it is easy to learn about this theory.
I cannot go into it in detail, but its premise is that cancer is a metabolic disease, and not a genetic one. Please take the time to look at the details before shooting me. 🙂

My only question here is whether anyone else has looked into this, and what do you make of it? Did you ever ask your oncologist about it?

Interested in more discussions like this? Go to the Cancer Support Group.

Part II

We started the cannabinoid regimen on October 22nd, and also started both Ivermectin and Fenbendazole the following day. Whether any of this may have worked as a cure had we started earlier is impossible to say, but I can say that Jack was correct regarding the palliative effect. By November 10th I'd been able to dramatically reduce the morphine (just half a pill per day) and the Lyrica (one per day). I switched primarily to Tylenol for pain, though her reports of pain seemed to be much less as well. This could have been owing in large part to the IPC having been removed a few days prior. Her pleural effusion had become “multiloculated” so the IPC wasn’t draining anymore, and I believe the catheter was rubbing against some of the major nerve pathways.

In-home hospice care began on November 21st and on November 23rd I reported to some friends: “The CBD/THC seems to be working as Jack suggested (or it's a God thing, or God working through the circumstances which led us to Jack. It's still God anyway as He's the one who created hemp;-). There is only some noticeable pain when trying to move her, like for changing her briefs. I have only given her 1000mg of Tylenol once yesterday morning and again this morning, and she is now fully weaned off of morphine and the Lyrica. Overall she’s pretty peaceful, all things considered. Hospice will of course be providing other stuff to have on hand like Ativan, fentanyl patch, liquid morphine, but are fully supportive of our approach for now. If/when there comes a point that I can’t administer the cannabinoids in any of their delivery forms we’ll switch to the standard-of-care stuff.”

As it turned out we did not have to switch to SOC medications with one minor exception about 90 minutes prior to her last breath. Also, the fact that the delivery forms are coconut oil-based meant that my wife did not have any issues with opioid-induced constipation, and as such we did not need to administer any supplements to address this. When she was still on the morphine and Tramadol we had to add magnesium.

My wife’s passing was blessedly peaceful, in our home, with no agitation at all and almost no noticeable pain. She was in the presence of me, our two sons, and her sister. I had not needed to give my her any pain meds, or any other meds, over the last 4 days or so of her life, with the exception of .25ml of morphine with about an hour and a half left. I even cut back the cannabinoid use from once per day to once every two days. She simply slept most of the time.

I did not have an autopsy performed but I believe her death resulted directly from “cancer cachexia.” I perhaps witnessed a metabolic race of sorts, with the cancer eating away at her energy stores faster than whatever food she could take in would offset that process. It’s entirely possible (perhaps even probable, owing to what the last labs taken on October 31st showed) that the cancer stayed confined to the pleura and chest wall. There was zero indication of metastases beyond that. Perhaps the cannabinoids were creating apoptosis, just not quite enough to cure. All speculation of course. Nothing more.

This path we took may have been too little, too late from a curative perspective, or even if done sooner it may not have been curative at all. But it has deepened my conviction to hew more closely to the things the natural world can provide rather than what the medical-industrial complex wants to sell us (though not outright rejecting all of it). I think the work of Seyfried et al will eventually show this, along with more research into cannabinoids and other natural products. I also believe, as my wife did, that she already had the deck stacked against her owing to her earlier high carb diet, diabetes, hypothyroidism, loss of her appendix a couple years ago, along with the chemotherapy and hormone therapy 10 years ago.

Again, I tell this story both for some more closure and to contribute another avenue to look into for whoever might be curious. A friend suggested telling this story would be a way to pay forward some knowledge I gained from Jack, things which I may never have known about were it not for the connection through my son to his friend’s dad. If you look into that patent I mentioned above (which also encompasses some 40 or more other patents) you may find yourself believing (especially if you are of a conspiratorial bent) that these patents are held so as to limit exposure to and public knowledge of completely natural processes and products for use with cancer. My own story is full of speculation and it would be a disservice to suggest anything but a simple, “It seems worth looking into.”

REPLY

Thanks for telling your story. I know it helped someone. God bless you and your sons.

REPLY
@wildapple50

Thanks for telling your story. I know it helped someone. God bless you and your sons.

Jump to this post

You're welcome, and thank you!

REPLY
@mddrm

Part II

We started the cannabinoid regimen on October 22nd, and also started both Ivermectin and Fenbendazole the following day. Whether any of this may have worked as a cure had we started earlier is impossible to say, but I can say that Jack was correct regarding the palliative effect. By November 10th I'd been able to dramatically reduce the morphine (just half a pill per day) and the Lyrica (one per day). I switched primarily to Tylenol for pain, though her reports of pain seemed to be much less as well. This could have been owing in large part to the IPC having been removed a few days prior. Her pleural effusion had become “multiloculated” so the IPC wasn’t draining anymore, and I believe the catheter was rubbing against some of the major nerve pathways.

In-home hospice care began on November 21st and on November 23rd I reported to some friends: “The CBD/THC seems to be working as Jack suggested (or it's a God thing, or God working through the circumstances which led us to Jack. It's still God anyway as He's the one who created hemp;-). There is only some noticeable pain when trying to move her, like for changing her briefs. I have only given her 1000mg of Tylenol once yesterday morning and again this morning, and she is now fully weaned off of morphine and the Lyrica. Overall she’s pretty peaceful, all things considered. Hospice will of course be providing other stuff to have on hand like Ativan, fentanyl patch, liquid morphine, but are fully supportive of our approach for now. If/when there comes a point that I can’t administer the cannabinoids in any of their delivery forms we’ll switch to the standard-of-care stuff.”

As it turned out we did not have to switch to SOC medications with one minor exception about 90 minutes prior to her last breath. Also, the fact that the delivery forms are coconut oil-based meant that my wife did not have any issues with opioid-induced constipation, and as such we did not need to administer any supplements to address this. When she was still on the morphine and Tramadol we had to add magnesium.

My wife’s passing was blessedly peaceful, in our home, with no agitation at all and almost no noticeable pain. She was in the presence of me, our two sons, and her sister. I had not needed to give my her any pain meds, or any other meds, over the last 4 days or so of her life, with the exception of .25ml of morphine with about an hour and a half left. I even cut back the cannabinoid use from once per day to once every two days. She simply slept most of the time.

I did not have an autopsy performed but I believe her death resulted directly from “cancer cachexia.” I perhaps witnessed a metabolic race of sorts, with the cancer eating away at her energy stores faster than whatever food she could take in would offset that process. It’s entirely possible (perhaps even probable, owing to what the last labs taken on October 31st showed) that the cancer stayed confined to the pleura and chest wall. There was zero indication of metastases beyond that. Perhaps the cannabinoids were creating apoptosis, just not quite enough to cure. All speculation of course. Nothing more.

This path we took may have been too little, too late from a curative perspective, or even if done sooner it may not have been curative at all. But it has deepened my conviction to hew more closely to the things the natural world can provide rather than what the medical-industrial complex wants to sell us (though not outright rejecting all of it). I think the work of Seyfried et al will eventually show this, along with more research into cannabinoids and other natural products. I also believe, as my wife did, that she already had the deck stacked against her owing to her earlier high carb diet, diabetes, hypothyroidism, loss of her appendix a couple years ago, along with the chemotherapy and hormone therapy 10 years ago.

Again, I tell this story both for some more closure and to contribute another avenue to look into for whoever might be curious. A friend suggested telling this story would be a way to pay forward some knowledge I gained from Jack, things which I may never have known about were it not for the connection through my son to his friend’s dad. If you look into that patent I mentioned above (which also encompasses some 40 or more other patents) you may find yourself believing (especially if you are of a conspiratorial bent) that these patents are held so as to limit exposure to and public knowledge of completely natural processes and products for use with cancer. My own story is full of speculation and it would be a disservice to suggest anything but a simple, “It seems worth looking into.”

Jump to this post

Thank you for sharing. I am a total believer in the healing powers of CBD. My son is a distributor of the product his chemist holds a patent for. They have many many true life stories of people, including one of the owners mothers who kicked cancer with their CBD products and a Keyto diet. Given the fact that every cancer type is specific to each person, it becomes a challenge to understand why it will work for some but not others.
We can only continue to pray that maybe someday, sooner rather than later, that eyes and ears in the medical field will open their minds to the idea that God put these alternative medicines on this earth for a reason.
So sorry to hear about the passing of your wife. Sending prayers to you and your family.
Thank you again for sharing ❤️🙏

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@isadora2021

@eileenham

Interesting thank you for sharing. Why each of us has cancer, have how each of us are affected by our cancer and how we respond to treatment (whether FDA approved or not) is fascinating.

Personally I was diagnosed stage 4 appendix cancer in 2021, had a radical hysterectomy and debulking surgery, 6 months of Folfiri and Avastin then in mid 2022 HIPEC with cytoreductive surgery and a peritonectomy. I’ve been NED since then (surveillance scans and blood tests now 4 monthly) with almost no side effects from treatments (just need to watch my hydration and fibre intake due to a colon resection).

No way am I suing my doctor!! He’s been fabulous. He’s encouraged me to live holistically through, and then post, treatment as adjuvant therapies. Referred me to various holistic experts. I eat a Mediterranean diet, exercise well, sleep well, practice mindfulness, minimise stress, enjoy Pilates, yoga and aromatherapy etc etc.

I don’t do Botox and try to live clean. However, I drink minimal red wine as per the Mediterranean diet and I do worry that I should drink none at all as I did through treatment. Alcohol does have a level of toxicity.

Hopefully that lifestyle will help prolong my life before recurrence. My cancer is rare, cause unknown and cannot be cured.

Who knows what I will do when my cancer returns. It will depend on the research and possibly my level of desperation

Jump to this post

I think your approach to diet is very healthy. Nothing guarantees complete success in avoiding or curing cancer. Stressing out about it can subtract years from one's life due to harmful effects on the immune system. My motto is everything in moderation and stick to what we know is good, nutritious and healthy, (including little treats now and then).

Happy New Year to all and good health in 2025.

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@gisellef

I think your approach to diet is very healthy. Nothing guarantees complete success in avoiding or curing cancer. Stressing out about it can subtract years from one's life due to harmful effects on the immune system. My motto is everything in moderation and stick to what we know is good, nutritious and healthy, (including little treats now and then).

Happy New Year to all and good health in 2025.

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@gisellef My thinking too. When I was diagnosed with stage 4 appendix cancer I came to terms with the possibility of dying then found an excellent medical team who followed integrative treatments (conventional and holistic, not alternative although I’m sure they would have worked with me on alternative inclusions if I’d wanted them as long as they did not mess with the effectiveness of my chemo or cause harm to me).

Other than rejecting oxaliplatin in my first line I left the chemo and immunotherapy up to my team.

I chose constructive denial: I did not want to know any test results - just a heads up if it started looking like we may need to look to 2nd line. I didn’t want the stress. I still have no idea what my numbers were!! I still choose not to know. I’m now NED that’s enough.

Instead, I focussed on what I could control. Primarily my diet, exercise and mindfulness.

I didn’t take any supplements. I asked my team if I should to help my body fight. They said no, my bloods were good, to keep eating whatever I was eating and supplements would just be expensive pee!!

I remain a strong believer in diet. I don’t know what went wrong in my appendix, of all places. I do know I lived with massive stress in my job - which I thought I enjoyed.

I have done keto in the past and while I lost a lot of weight on it I found it impractical and a hassle trying to socialise and stay in ketosis. I also felt “off” and even though I was super fit cardio wise I tired easily while doing keto. It was not something I wanted to do again. It didn’t suit me.

Research keeps improving. Just one example is that, now medical cannabis has been legalised in many places, it’s also now possible for scientists actually to do the research and tinker how to make the most of its constituents.

Prayers and good wishes for everyone 🙏😊

REPLY
@myboysthree

Thank you for sharing. I am a total believer in the healing powers of CBD. My son is a distributor of the product his chemist holds a patent for. They have many many true life stories of people, including one of the owners mothers who kicked cancer with their CBD products and a Keyto diet. Given the fact that every cancer type is specific to each person, it becomes a challenge to understand why it will work for some but not others.
We can only continue to pray that maybe someday, sooner rather than later, that eyes and ears in the medical field will open their minds to the idea that God put these alternative medicines on this earth for a reason.
So sorry to hear about the passing of your wife. Sending prayers to you and your family.
Thank you again for sharing ❤️🙏

Jump to this post

@myboysthree I have read many testaments from people who have successfully used cbd gummies for pain relief and to sleep. They swear by them.

I’ve also read testaments from others who have suffered adverse side effects. The most bizarre was a post I read today in another group I belong to where someone who had been taking Rick Simpson Oil for only a month according to the instructions provided with the RSO. Already she seems to have developed CHS and was desperate to know what to do or where to turn. Cannabis is still illegal where she lives.

I’m no doctor so I’m not promoting the use or saying it should not be used. All I am saying is it’s important to be aware that not everyone is able to safely use cbd oil and that medical research is still catching up now that research can finally be legally done
https://jcannabisresearch.biomedcentral.com/articles/10.1186/s42238-019-0013-x
https://my.clevelandclinic.org/health/diseases/21665-cannabis-hyperemesis-syndrome

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I am of the belief cancer is a metabolic disease. There are many researchers who claim the history as well. there's many very good books on the subject. Most diseases are caused by some issue of a body that's not functioning as it was intended. When nutrition is addressed symptoms reduce or reverse.

I also don't believe you can starve cancer. The diet we eat will strengthen our body or starve our body of nutrients. I'm using an integrated approach to my cancer treatments. My thought is surgery and chemotherapy gave me time to figure out how I want to live knowing I had an aggressive cancer that is resistant to conventional therapy. I decided that it's my responsibility to live in a manner that will support my body. I am working with both a functional/holistic Doctor and an oncologist. I'm still early in my cancer experience and I'm not ready to try unproven, but interesting treatments weather that's a medical trial or alternative treatments.

I started following a metabolic syndrome diet before starting chemotherapy. It's not that easy especially if it's foreign to your old food patterns. I also used fast mimicking product around chemotherapy. I stayed metabolically healthy through the 4 1/2 months of chemotherapy. The main side effect was the diminished immune system and you don't feel that until there is an infection.

Going forward I plan to stay as close to this diet as possible. I don't think I can actually get to a point of ketosis. It's to difficult to cut out carbohydrates to 20 or 40 grams per day and keep the diet diverse and enjoyable.

I am also trying to follow the he 150 minutes per week of moderate exercise. There is also some pretty compelling research for exercise after a cancer diagnosis.

I'm trying to limit exposure to toxins but that's nearly impossible.

I've read some great books written by either PHDs or MDs that try to convince the reader that these are valid approaches. We will never have the level of research that chemical drugs have. Who would fund that the Leafy Green industry?

Fuel your body for success. I am. I've lost so much weight and I was just outside my BMI when I started. Now I'm skinny, but muscular. I'm not wasting. If it weren't for the wrinkles I look like I did 40 years ago. Because what I eat is dense in nutrients and low on calories I can not over eat.

I miss pineapples and I miss potatoes the most. I have cheat moments when I'll take a few off my daughter or Mel's plate. I've also ate chocolate pie at Thanksgiving. I've tried to cut highly processed foods. It's difficult because my partner keeps bringing chocolate bars and potato chips into the house. It's really hard when people around you don't get it and are commenting on my food choices and figure. "You need to put on weight"

Social networks are important, but the ones I have aren't always supportive of my path to health.

Denise

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@denisestlouie

I am of the belief cancer is a metabolic disease. There are many researchers who claim the history as well. there's many very good books on the subject. Most diseases are caused by some issue of a body that's not functioning as it was intended. When nutrition is addressed symptoms reduce or reverse.

I also don't believe you can starve cancer. The diet we eat will strengthen our body or starve our body of nutrients. I'm using an integrated approach to my cancer treatments. My thought is surgery and chemotherapy gave me time to figure out how I want to live knowing I had an aggressive cancer that is resistant to conventional therapy. I decided that it's my responsibility to live in a manner that will support my body. I am working with both a functional/holistic Doctor and an oncologist. I'm still early in my cancer experience and I'm not ready to try unproven, but interesting treatments weather that's a medical trial or alternative treatments.

I started following a metabolic syndrome diet before starting chemotherapy. It's not that easy especially if it's foreign to your old food patterns. I also used fast mimicking product around chemotherapy. I stayed metabolically healthy through the 4 1/2 months of chemotherapy. The main side effect was the diminished immune system and you don't feel that until there is an infection.

Going forward I plan to stay as close to this diet as possible. I don't think I can actually get to a point of ketosis. It's to difficult to cut out carbohydrates to 20 or 40 grams per day and keep the diet diverse and enjoyable.

I am also trying to follow the he 150 minutes per week of moderate exercise. There is also some pretty compelling research for exercise after a cancer diagnosis.

I'm trying to limit exposure to toxins but that's nearly impossible.

I've read some great books written by either PHDs or MDs that try to convince the reader that these are valid approaches. We will never have the level of research that chemical drugs have. Who would fund that the Leafy Green industry?

Fuel your body for success. I am. I've lost so much weight and I was just outside my BMI when I started. Now I'm skinny, but muscular. I'm not wasting. If it weren't for the wrinkles I look like I did 40 years ago. Because what I eat is dense in nutrients and low on calories I can not over eat.

I miss pineapples and I miss potatoes the most. I have cheat moments when I'll take a few off my daughter or Mel's plate. I've also ate chocolate pie at Thanksgiving. I've tried to cut highly processed foods. It's difficult because my partner keeps bringing chocolate bars and potato chips into the house. It's really hard when people around you don't get it and are commenting on my food choices and figure. "You need to put on weight"

Social networks are important, but the ones I have aren't always supportive of my path to health.

Denise

Jump to this post

I wholly support you and your diet/exercise program. I'm following a similar path to yours, but I also take supplements suggested by my naturopath. These are quercetin, reishi capsules, low dose Naltroxone, and melatonin. I also take Vit C, D3 with K2, and calcium. I've cut down on dairy -- still have it my coffee, red meat, and have added a lot more nuts and seeds to my diet.
Taken together, these modifications and additions have helped: I had severe pain in my pelvis and started bleeding well after my hysterectomy and chemo therapy. After taking the supplements for a while, the bleeding and the pain have stopped.
As there is a new walnut-sized growth that has appeared in my vaginal vault, I will probably take part in a clinical study, which I'm ambivalent about. Will have to wait and see what my next CT scan says and how well the minute dose of radiation to the new growth succeeds.

REPLY
@denisestlouie

I am of the belief cancer is a metabolic disease. There are many researchers who claim the history as well. there's many very good books on the subject. Most diseases are caused by some issue of a body that's not functioning as it was intended. When nutrition is addressed symptoms reduce or reverse.

I also don't believe you can starve cancer. The diet we eat will strengthen our body or starve our body of nutrients. I'm using an integrated approach to my cancer treatments. My thought is surgery and chemotherapy gave me time to figure out how I want to live knowing I had an aggressive cancer that is resistant to conventional therapy. I decided that it's my responsibility to live in a manner that will support my body. I am working with both a functional/holistic Doctor and an oncologist. I'm still early in my cancer experience and I'm not ready to try unproven, but interesting treatments weather that's a medical trial or alternative treatments.

I started following a metabolic syndrome diet before starting chemotherapy. It's not that easy especially if it's foreign to your old food patterns. I also used fast mimicking product around chemotherapy. I stayed metabolically healthy through the 4 1/2 months of chemotherapy. The main side effect was the diminished immune system and you don't feel that until there is an infection.

Going forward I plan to stay as close to this diet as possible. I don't think I can actually get to a point of ketosis. It's to difficult to cut out carbohydrates to 20 or 40 grams per day and keep the diet diverse and enjoyable.

I am also trying to follow the he 150 minutes per week of moderate exercise. There is also some pretty compelling research for exercise after a cancer diagnosis.

I'm trying to limit exposure to toxins but that's nearly impossible.

I've read some great books written by either PHDs or MDs that try to convince the reader that these are valid approaches. We will never have the level of research that chemical drugs have. Who would fund that the Leafy Green industry?

Fuel your body for success. I am. I've lost so much weight and I was just outside my BMI when I started. Now I'm skinny, but muscular. I'm not wasting. If it weren't for the wrinkles I look like I did 40 years ago. Because what I eat is dense in nutrients and low on calories I can not over eat.

I miss pineapples and I miss potatoes the most. I have cheat moments when I'll take a few off my daughter or Mel's plate. I've also ate chocolate pie at Thanksgiving. I've tried to cut highly processed foods. It's difficult because my partner keeps bringing chocolate bars and potato chips into the house. It's really hard when people around you don't get it and are commenting on my food choices and figure. "You need to put on weight"

Social networks are important, but the ones I have aren't always supportive of my path to health.

Denise

Jump to this post

Hi Denise:
All I can say is that you are an inspiration to all. I agree that it would be immensely difficult to achieve the dietary targets that your eating plan demands. In my humble opinion it may be enough to just cut out the junk food if you can portion control the higher carb foods plus add high nutritionally dense foods. The exercise component is very important as well as your ability to remain at a good BMI.
As far as exposure to chemicals is concerned, there are a couple of steps you and anyone on this thread can take if not doing so already:

1. Filter your water.
2. Buy more natural cleaning products that have less toxicity. Pesticides and herbicides also can harm the body. If use is unavoidable at least wear a mask and store these products where they are safely away from day to day access.
3 There are many problematic additives in creams, hair colour and other beauty products. There are wonderful products that do not include plastics. Read labels for this information.
4 Store foods in glass containers rather than plastic if possible.
5 Check your house for levels of Radon gas, which is a factor in lung cancer incidence.
6. Processed food that has a long shelf life contains preservatives that can be hard to metabolize. Make them from scratch when possible.
These are just a few things that we can control.
Best wishes.

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