LVOT Gradient Increase

Posted by joycehocm @joycehocm, 5 days ago

Hi all - I am a 74 year old female who was diagnosed with HOCM a year ago - at Johns Hopkins which is a COE. My cardiologist put me on jardiance and verapamil which has been wonderful - no side effects and a great decrease in breathlessness. I am only breathless after meals. However, a recent echo shows that my LVOT has increased from 18 to 83 at rest. Probably this is a lot. I haven't talked to my cardiologist a Hopkins yet but will next week. Meanwhile, can anyone tell me anything about what this high gradient typically means regarding treatment? Thanks!

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ebony3 | @ebony3 | 4 days ago

My LVOT increased with my last echo. My provider corresponded with me so I think perhaps you should contact your cardiologist and ask why.
My dr. thought it could have been caused by a recent surgery. So we shall see with my next echo.
I have had no notable symptoms that might indicate that the obstruction had increased.

jmr091805 | @jmr091805 | 3 days ago

Has your hypertrophic cardiomyopathy become obstructive? And if so, are you taking Camzyos?

debrasheila | @debrasheila | 3 days ago

Mine has and I started camzyos about a month ago. Gradient down from 53 to 9.

joycehocm | @joycehocm | 3 days ago

In reply to @jmr091805 "Has your hypertrophic cardiomyopathy become obstructive? And if so, are you taking Camzyos?" + (show)

@jmr091805 yes - I have HOCM but since the LVOT was 18 at the last echo my cardiologist did not put me on Camzyos (yet?). This steep increase is odd since I am not having additional symptoms. I have sent him an email and I am sure he will respond today or Monday. Just looking for input and education from the Mayo community. Thanks!