1. < MAC & Bronchiectasis

Losing voice on tobramycin

Posted by Stella Tucson @fraytv, Mar 5, 2023

This is my third attempt to post this question so bear with me. Dr is starting me on tobramycin, have read about the side effects. Question is for those who lost their voice was it permanently or temporary & how many days were you without a voice? Also dr said I would be on it 3 months, & I have read you take it for 28 days then go off, and then go back on it again. I am already experiencing some hearing loss due to antibiotics I was on. Is the tobramycin as bad as the big 3, I already went through that 12 years ago? Any advice would be appreciated! Thank you!

Interested in more discussions like this? Go to the MAC & Bronchiectasis Support Group.

pjas972j | @pjas972j | Mar 6, 2023

I've been on inhaled tobramycin since last July - 2 weeks on, 2 weeks off, as per NJH prescription. I didn't lose my voice the first couple of rounds, but now lose it for about a week but it comes right back. My ENT advised me to nebulize 0.9% saline after the Toby as a vocal cord rinse and that seems to be helping. I've never been on the Big 3 but Toby has not been difficult to manage. I hope you feel better soon!

REPLY
1 reply
Stella Tucson | @fraytv | Mar 6, 2023
In reply to @pjas972j "I've been on inhaled tobramycin since last July - 2 weeks on, 2 weeks off, as..." + (show)
@pjas972j

I've been on inhaled tobramycin since last July - 2 weeks on, 2 weeks off, as per NJH prescription. I didn't lose my voice the first couple of rounds, but now lose it for about a week but it comes right back. My ENT advised me to nebulize 0.9% saline after the Toby as a vocal cord rinse and that seems to be helping. I've never been on the Big 3 but Toby has not been difficult to manage. I hope you feel better soon!

Jump to this post

Thank you for the reply.

REPLY
b4499 | @b4499 | May 10 12:05pm

Does it restore your voice?

REPLY
1 reply
Stella Tucson | @fraytv | May 10 3:33pm
In reply to @b4499 "Does it restore your voice?" + (show)
@b4499

Does it restore your voice?

Jump to this post

I eventually got my voice back but it was after I stopped using the Toby.

REPLY
pegs | @pegs | May 11 4:13pm

Hi Stella,
I was on Tobi since last October, one week/month and lasted 7 months. Yes, I'd lose my voice every week, then would get it back in another week. Finally, I had an intolerance to that drug, but everyone is different, nothing to do with losing your voice. I am now off of Tobi and doing airway clearance 2X/day with 7% hypertonic saline hoping to keep the lungs clear. Best wishes, Peg

REPLY
Please sign in or register to post a reply.