Looking for advice: Could this be MGUS, because of low m-spike?

Posted by oliviahutson @oliviahutson, Aug 1, 2023

Hello,
I am hoping someone can help better understand my labs and symptoms.
IgA Kappa with .88 m-spike
IgA 1000
Blood in urine
Low RBC
High number in the Betta region
Lower lumber MRI shows heterogeneous bone marrow noted within the pelvis?? Don’t know if that means anything.
Extreme pain in pelvis, lower back and right ribs
Chronic sinus infections
Dizzy all the time
Extreme fatigue
Night sweats
Shortness of breath
Heart pains (sometimes)
Numbness/tingling in both lower legs and feet
Ringing in ears
Vision issues
Weakness in legs and arms
Weight loss 22 lbs in 6 months

Could this just be MGUS, because of low m-spike??

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Honestly, hematology is such a complicated area no one but a specialist can tell you those answers and interpret your lab findings.
It could be MGUS, but the bone pain, weight loss, night sweats & extreme fatigue is a little concerning. Have you met with a myeloma specialist to discuss those?
I know we often get results on the portal before the appointment which can cause a lot of anxiety while we wait.
Let us know what you find out, okay? Leslie

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The low RBC could be due to blood in the urine; perhaps a urinary tract infection. Any fever?

"Extreme pain in pelvis, lower back and right ribs" could also indicate kidneys.

Are you diabetic?

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@leslie2121

Honestly, hematology is such a complicated area no one but a specialist can tell you those answers and interpret your lab findings.
It could be MGUS, but the bone pain, weight loss, night sweats & extreme fatigue is a little concerning. Have you met with a myeloma specialist to discuss those?
I know we often get results on the portal before the appointment which can cause a lot of anxiety while we wait.
Let us know what you find out, okay? Leslie

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Thank you for responding. I have two different doc appointments with hematologist/oncologist on two weeks.
Thank you so much for responding!

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@corsair9

The low RBC could be due to blood in the urine; perhaps a urinary tract infection. Any fever?

"Extreme pain in pelvis, lower back and right ribs" could also indicate kidneys.

Are you diabetic?

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I was a fit 42 yr old CrossFitter. Not diabetic. Had a hysterectomy so not blood from menses. No UTI. They did all the tests to see if I had low iron. I do not. I had a kidney disease as a kid and this is a deep bone pain, not kidney pain. I

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@corsair9

The low RBC could be due to blood in the urine; perhaps a urinary tract infection. Any fever?

"Extreme pain in pelvis, lower back and right ribs" could also indicate kidneys.

Are you diabetic?

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And thank you for responding to me.

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@oliviahutson

And thank you for responding to me.

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"And thank you for responding to me"

For sure. I was just pointing out some of the obvious potential issues. You might consider a bone marrow biopsy if you haven't already had one. I pray that you find a workable resolution. Blessings :^) IR

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@corsair9

"And thank you for responding to me"

For sure. I was just pointing out some of the obvious potential issues. You might consider a bone marrow biopsy if you haven't already had one. I pray that you find a workable resolution. Blessings :^) IR

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Thank you!! I haven’t had a bone marrow biopsy yet. Thinking that’s the next step.

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@oliviahutson Welcome to Mayo Clinic Connect. I'm glad to see some members have already stepped up and answered your concerns. It's always difficult when we don't know what might be happening with us, and trying to cobble a variety of symptoms together can be confusing.

May I suggest you keep a journal of the symptoms you experience. Include time of day, before/after meal/activity, intensity. Write down any questions that come to mind; don't rely on your memory. While your hematologist/oncologist may not be able to give you something definite right away, any helpful notes you take will be a key to getting things figured out!

As an LEO wife, you probably are aware of the thought process to look at everything, and not jump to conclusions until all the facts are in. The same goes here. Do you have any questions I can help you with?
Ginger

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@gingerw

@oliviahutson Welcome to Mayo Clinic Connect. I'm glad to see some members have already stepped up and answered your concerns. It's always difficult when we don't know what might be happening with us, and trying to cobble a variety of symptoms together can be confusing.

May I suggest you keep a journal of the symptoms you experience. Include time of day, before/after meal/activity, intensity. Write down any questions that come to mind; don't rely on your memory. While your hematologist/oncologist may not be able to give you something definite right away, any helpful notes you take will be a key to getting things figured out!

As an LEO wife, you probably are aware of the thought process to look at everything, and not jump to conclusions until all the facts are in. The same goes here. Do you have any questions I can help you with?
Ginger

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Thank you so much! My husband has encouraged me to write down everything (detective/LEO mind) lol.
I am trying to bring everything to the table whne I meet with my two hematologist/oncologist next week. I have a tendency to over look symptoms. Maybe because I am used to being uncomfortable from CrossFit for years. Lol

I guess now, I need to recognize and write down.

Thank you for your support Ginger! God bless all of you! Grateful

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