Long term effects of heavy antibiotics on motivation, personality

Many years ago I suffered from a burst intestine while in hospital. Was rushed into emergency surgery, cut me from sternum to groin, removed all insides, flushed me out, and was in ICU for several days on extremely heavy antibiotics.

Prior to this emergency, I was extremely active, positive, motivated, and lived a full, exciting, adventurous life. After this procedure, I lost my usual energy levels, motivation, zest for adventure and life. It has never returned, I am not "myself" as I know I used to be, and as everyone knew me to be. I believe the antibiotics destroyed my gut biome, and I've never been able to get that same biome back again, despite taking many pro and pre biotics etc.

I recently discovered an alternative drug to Ritalin called Vyvanse, and when I take it, I am back to my old self, got energy, drive, motivation, positive outlook, focus etc, and life is as good as it was pre my emergency surgery.

Has anyone else experienced permanent personality/mood/motivation problems etc following heavy life-saving antibiotic treatment?