Keytruda side effects: How did you manage them?

62 year-old male, previously in good health and physically active until my world was turned upside down with a diagnosis of Stage 3b Clear Cell renal cell carcinoma in December of 2024. Complete right nephrectomy at the end of that month, now getting immunotherapy in hopes of preventing the cancer from returning or spreading.

3 weeks into Keytruda (I’m on 400mg every 6 weeks) and main side effects so far are joint pain, with tingling/slight numbness feeling in left hand fingers. Joint pain seems more centered in left hand and left knee - ironically my left wrist has been broken twice and my left knee has been operated on twice. I also have low back pain, where I’ve had herniated disks in the past.

Does anyone know if this correlates to the drug being most likely to affect areas where arthritis may have been starting? And does anyone who has experienced the pain and tingling/numbness in their hand(s) had it improve during immunotherapy, stay the same, or get worse?

I’m asking largely because I can’t work with the symptoms as they are (I need control for fine motor skills), but could return to work when the symptoms are gone. Thanks in advance for the replies.