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on my third dose of the big 3 what can i expect for common side effects and how long before i feel any better ???? and are all of you taking the 3 the same day how are you dosing ??
I am taking the Big 3 3 days a week, Monday, Wednesday and Friday…..
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I am starting the Big 3 today after a long Covid delay. My Dr. is introducing them one at a time, but I am wondering what time of day you take your drugs? With or without food? I am requesting clarification from the physician but curious to know what the schedule looks like for others. Thank you! Nancy
My pharmacist was very helpful in scheduling my Big 3. I take every Monday, Wednesday and Friday – 2 Rifampin first thing in the morning ( no food ), then 3 1/2 Ethambutol at lunch and then 1 Azithramycin at dinner. Hope this helps and I absolutely hope you can tolerate your meds. Best of luck to you !
@n4seth The schedule for taking the Big 3 has to be what is best for you and how you can tolerate them. What Toni1132 said is probably quite good. The only thing I would add is if you need a probiotic you should probably take that first in the morning on an empty stomach. Rifampin can be one hour before or two hours after a meal with a full glass of water. Ethambutol and azithromycin can be taken after breakfast with a full glass of water eight hours before or four hours after your daily multivitamin. Your vitamins and probiotics should be separated from the antibiotics by at least four hours. NOW foods probiotic-10 or Ultra Jarro- Dophilus (50 billion per capsule) are good ones. I follow a schedule a former mentor used during her MAC journey. irene5
Everyone has great suggestions. Welcome to this group. You will find a lot of support here. I learned about nebulizing 7% sodium chloride here and it has really helped. I take Rifampin first thing and I split up the other two. Ethambutol at noon with lunch and Azithromycin at dinner. Taking more than 3 pills at a time can really upset your stomach. But, everyone is different. Welcome and hang in there!
Thank you to everyone who has replied. Day 1 went well…..tomorrow I add the ethambutol. Keeping my fingers crossed!
Finishing up on 15 months of the Big 3 at the end of May. At least I hope so. CT of Chest coming up soon so I will know if I can quit altogether. IDC doc had already reduced the azithromycin to one/day as I was showing signs of clearing. I have taken a good probiotic and ClearLungs by Ridgecrest every night. Rifampin before breakfast, azithromycin 1 hr after and ethambutol 2 hrs. after. Luckily, no side affects other than a bit of hearing loss – but I guess to be expected at 73! One thing I've done which might help you is I was able to considerably reduce the cost of the drugs. I had my dr. request approval of a Tier Exception by my insurance carrier Humana. They agreed to reduce to a Tier 1 copay which lowered my copay considerably. Best of luck with the antibiotics – get plenty of exercise and fresh air – breathe deeply!!
Thank you…. and congratulations on nearing the end!
Hi there! Was wondering how you are doing on the ethambutol?
Thanks for checking in! I am keeping my fingers crossed-so far, so good. I just completed my first week on all three drugs and have had mild nausea and headache along with my perpetual fatigue. On my off days, I am doing well although I am experiencing more coughing and insomnia than normal. I am guessing it may have nothing to do with the medication and everything to do with the huge amount of pine pollen floating around right now. All in all, I expected the drugs to be much worse and if it continues like this, it is doable. Nancy
@n4seth That’s 3/4 of the battle – being able to tolerate the Big 3. Yay you! irene5
@n4seth Nancy – Are you using a good probiotic to help your digestive system as you continue on the antibiotics? In my experience, which one doesn't matter as much as using regularly.
Sue, thanks for checking in. Not only am I drinking kefir, eating sauerkraut and yogurt, I am learning to cook with miso. Also taking Florajen. I will try anything that helps! Nancy
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