1. < Kidney Conditions
Profile picture for kayabbott

Jardiance for stage 3a CKD or Acute Kidney Injury (AKI)

Posted by kayabbott @kayabbott, Jul 11, 2025

A month after a nasty case of Norovirus on 12/23 my creatinine levels ramped up and my eGFR went from 77 to 35. Other than being 71 yo, I have no risk factors for kidney disease, not family history, BP, pre-diabetic, or diet. I have elevated proteins in my urine now so started on 10 mg Jardiance sglt2 inhibitor (I don't tolerate ACE II) to protect my cardiovascular system and slow/stop progression of CKD or AKI. I will find out side effects, but was wondering if any of you have had irksome ones. My glucose has never been elevated so I'll probably carry hard candies now because Jardiance decreases blood glucose. I will have to drink more water and start chugging cranberry juice (preventative for UTI, lessens the ability of bacteria to adhere to urethral walls). Being a lab rat is getting a bit tiring.

Interested in more discussions like this? Go to the Kidney Conditions Support Group.

Profile picture for happyquilter
happyquilter | @happyquilter | 2 days ago

I am also on Jardiance and have CKD3b. My doctors didn't bother to tell me anything about my kidneys until they reached stage 3b. Great Florida doctors. Also deal with blood pressure and sugar. Was just put on a remote blood pressure monitor by my Nephorologist, taking my BP every morning when I get up and transmitting it to the doctor (or monitoring center) electronically. The kidney doctor feels this is necessary so it's now a daily routine. Anyone else ever had to do this? If so, for how long? I don't have any established time frame from my doctor just instructions to do it every morning first thing. No idea what this costs me either.

REPLY
Profile picture for martychambers
martychambers | @martychambers | 1 day ago
In reply to @mcgirene "I was put on forxiga to improve my kidneys. After about two weeks I felt awful...." + (show)
Profile picture for mcgirene @mcgirene

I was put on forxiga to improve my kidneys. After about two weeks I felt awful. Blood test revealed an eGFR of 23. I’d been stable at 30-33 for years. Nephrologist told me stop taking forxiga immediately. She said for some people with CKD it makes things worse. She said that I would probably need to take Jardiance eventually but not now. Final thing she said was that trying to treat lower side eGFR before it is critical can cause more problems. So I am waiting for things to get worse before I take any new treatments.

Jump to this post

@why wait to start Jardiance. Wish I had started it 3 years ago when it was approved to slow ckd. Take GennaMD a cranberry juice extract with 36 mg the minimum. No side effects.

REPLY
1 reply
Profile picture for mcgirene
mcgirene | @mcgirene | 1 day ago
In reply to @martychambers "@why wait to start Jardiance. Wish I had started it 3 years ago when it was..." + (show)
Profile picture for martychambers @martychambers

@why wait to start Jardiance. Wish I had started it 3 years ago when it was approved to slow ckd. Take GennaMD a cranberry juice extract with 36 mg the minimum. No side effects.

Jump to this post

@martychambers I was told by my nephrologist that I would be taking it eventually but it was premature to start now. I trust her - she’s an excellent doctor. I’m glad it is working for you. I like to hear good news! Cheers

REPLY
Profile picture for Ginger, Volunteer Mentor
Mentor
Ginger, Volunteer Mentor | @gingerw | 1 day ago
In reply to @nanigena "I hope your kidney function improves as you recover. Many people tolerate Jardiance well, but it's..." + (show)
Profile picture for nanigena @nanigena

I hope your kidney function improves as you recover. Many people tolerate Jardiance well, but it's a good idea to watch for dehydration and UTIs, especially after an illness. I also found it helpful to keep track of my lab results using a Creatinine Clearance (CrCl) Calculator alongside my eGFR before discussing them with my doctor. Wishing you the best with your follow-up tests.

Jump to this post

@nanigena Welcome to Mayo Clinic Connect! You're right, keeping track of our labwork, and watching for trends in results, will helps us understand what is going on.

What brought you to Mayo Clinic Connect? What prompted you to join in to respond? What CKD condition do you live with?
Ginger

REPLY
Please sign in or register to post a reply.