Iwasaki Lab Shows Long COVID Antibodies Trigger Pain in Mice — The Dat

Indeed, when you answer the question: How's your immune system? you will be on the right path to solving your pain issues. Please consider a complete T-Cell work up with one blood draw and find out.
https://www.news-medical.net/news/20260324/Long-COVID-antibodies-induce-persistent-pain-like-symptoms-in-mice.aspx
Summary Antibodies that transfer symptoms:
In the study, researchers injected immunoglobulin G (IgG) - a major class of antibodies – derived from blood of 34 patients with Long COVID, into mice. The result was striking as the animals developed persistent pain-like hypersensitivity. This effect lasted for at least two weeks. Even more notable, IgG collected from the same patients two years later reproduced the same symptoms when administered to mice.

This finding suggests that the underlying disease mechanism may persist long after the initial infection, potentially explaining why many patients experience long-term symptoms."

Prof. Niels Eijkelkamp, PhD, co-study lead, Center for Translational Immunology, UMC Utrecht