Is anyone else confused about all those inhalers?
Is Anyone Else Confused by all the inhalers prescribed for our lungs?
After a lengthy visit with my pulmonologist yesterday, I came away with a new set of medications and a whole lot of confusion!
This morning, I sat down and made list of all the drugs I use/have used, all the drugs we talked about yesterday, and several that have been suggested or mentioned here on Connect. Then I got busy and figured out what they are and why we use them.
Here is a summary…incomplete for sure, listing the classes of drugs with a short explanation of each class, and individual drug names (not the Brand Name or Combo name).
“Rescue” drugs – may be inhalers, or in some cases nebulizer solutions
Short Acting Beta Agonist (SABA) Opens airways quickly, relaxes airways, but doesn’t last long
• Albuterol (Common Brand Names: ProAir, Ventolin, Proventil)
• Levalbuterol (Xopenex)
• Salbutamol
Short Acting Muscarinic Agonist (SAMA) Like SABA, opens airways, or prevents bronchospasm. Less often used than SABA
• Irpatropium Bromide (Atrovent)
• Tiotropium Bromide (Spiriva)
Long Term or Daily Use Medications
Inhaled Steroids Direct dosage to lungs compared to oral steroids which are systemic. Reduces inflammation which helps keep airways open.
Inhaled Corticosteroid (ICS)
• Budosenide (Pulmicort, Entocort, Rhinocort)
• Mometasone (only in combinations)
Inhaled Glucosteroid (IGS)
• Fluticasone Propionate (Flovent, Allerflo)
Long Acting Beta Agonist (LABA) Acts to keep airways open – usually used in combination with an inhaled steroid
• Formoterol Fumarate (Foradil)
• Salmeterol Xinafoate (Serevent)
• Vilanterol (only in combinations)
Long Acting Muscarinic Agents (LAMA) Relaxes muscles around airways for 12-24 hours to reduce asthma attacks
• Tiotropium bromide (Spiriva)
• Umeclidinium bromide (Incruse)
Here is a summary of the most commonly prescribed Name Brand medications and what drugs are in each one.
Advair - Fluticasone propionate (IGS), Salmeterol (LABA)
AirDuo - Fluticasone propionate (IGS), Salmeterol (LABA)
Anoro- Umeclidineum (LAMA), Vilanterol (LABA)
Breo - Fluticasone Furoate(ICS), Vilanterol (LABA)
Combivent - Irpatropium Bromide (SAMA), Albuterol (SABA)
Dulera - Mometasone (ICS), Formoterol (LABA)
DuoNeb - Irpatropium Bromide (SAMA), Albuterol (SABA)
Nebulizer Solution
Symbicort - Budosenide (ICS), Formoterol (LABA)
Trelegy - Fluticasone (IGS), Umeclidinium (LAMA), Vilanterol
(LABA) Explanation
This is not a list of inhalers you should use, just a list of those that are often used for Asthma, Bronchiectasis & COPD - some of us have only one of these diseases, some of us have several.
I have attached a PDF file if you would like to print this list.
Sue
Interested in more discussions like this? Go to the MAC & Bronchiectasis Support Group.
Connect

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629914/
"Fluticasone propionate is associated with an increased risk of pneumonia compared to budesonide in patients with COPD. In addition, the risk of pneumonia increased at higher ICS doses. Therefore, the types of ICSs and ICS doses need to be carefully considered in the treatment of COPD with ICS."
Even though this is a COPD study, having bronchiectasis we share symptoms with COPD.
Essentially, if one has asthma better to be on a budesonide inhaler vs. a fluticasone inhaler. Important to work with doctor to find the minimum effective dose.
Thanks. I didn't think so but it's always nice to have reassurance!
Albuterol alone is not a steroid.
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1 ReactionI prefer nebulizing the albuterol also for the added "moisture". Maybe that's a psychological effect but if so, that's ok too. However, I never used it or needed it as a rescue inhaler sort of thing. I assume that is for someone that has asthma? And, if I understand it correctly, albuterol used for nebulizing is not a steroid right?
Albuterol is available in vial form for use in a nebulizer and also in a inhaler.
I prefer the nebulizer as it is mixed with saline and slowly administered over 10 minutes but is difficult if you are in the go. The small handheld inhaler is good for traveling or rescue type applications
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2 ReactionsI read over this post and the other comments and I must say it was enough to make my head spin! I am very thankful I do not have asthma to deal with along with MAC and Bronchiectasis. I empathize with those that have a more complicated picture to sort out. I did want to ask, after reading, I saw Albuterol (which I use twice daily followed by 7% saline as part of routine airway clearance) was listed as a rescue inhaler. However, it is not a steroid, just a bronchodilator? Just making certain as I don't want to have anything to do with steroids if not necessary! Some things are unavoidable, as with those with asthma must use something, but in my case I don't want to unnecessarily complicate the situation.
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1 Reaction@harrynsc Well you are probably not wrong. Steroid inhalers do a lot of good, but steroids as a whole increase your risk. I only recently learned that - well within the past year after getting RSV. @scoop is correct about the albuterol and saline. It’s a catch 22 really. You need to get rid of all the yuckiness in your airways. There is a great article @rstel7272 shared a few months ago on the subject. Pulmonologists who know this fact about steroids ( all should) try to do a balancing act with it all, but we do need to breathe! @irene5
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2 ReactionsI was on Trelegy for two years and I'm convinced that the steroid in it dialed down
my immune system and that's why I got MAC.
Harry
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2 ReactionsThat site is something I'll revisit. Since we suffer with "rare" disease it's difficult to know if something works for one if it will work for the other. The creator seems to have significant co-morbidities, further blurring things. While medicine today is far from perfect, it is evidence based, with many drugs taking years to research, develop, test and approve. How I wish I could throw away the inhalers, and only use albuterol and 7% saline! Have you tried doing that?
Scoop, are you a member of the facebook group "lung matters"? If not, you should join and read the guide lines, especially the chapter "𝗕𝗿𝗼𝗺𝗶𝗱𝗲𝘀 & 𝗦𝘁𝗲𝗿𝗼𝗶𝗱𝘀". This chapter saved my life.
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