How to beat diabetes on prednisolone?

Posted by mmr1984 @mmr1984, Dec 20, 2020

If you have steroid induced diabetes then this may be for you. The key is to prolong the time between prednisolone dose and largest meal as much as possible. Before I used to take prednisolone with tacrolimus in am and by lunch time the two meds would be really high in my blood. Both meds synergistically spike blood sugar so when I had my heavy meal.at lunch my blood sugar spiked even after taking diabetic meds. So, what I did was take the heavy meal that is lunch for me at a time when the levels of prednisolone and tacrolimus are low in my blood. Prednisolone becomes low after 12 hours you take it so I started taking both tacrolimus and prednisolone at pm and very light meal if any I take at night. Now i don’t need to take any diabetic meds even after lunch. The trick is the two meds tacrolimus and prednisolone are no higher in my blood when I take largest meal. You can give this technique a try. Also, my hunger has lessened.

@mmr1984 Welcome to Mayo Connect. I see you have been here just a short while. Congratulations on your liver transplant. It sounds like things are going well for you!

Thank you for telling us about your medication finds. I am interested in hearing how you came about finding out to do this? What has the response been from your transplant team?
Ginger

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@gingerw

@mmr1984 Welcome to Mayo Connect. I see you have been here just a short while. Congratulations on your liver transplant. It sounds like things are going well for you!

Thank you for telling us about your medication finds. I am interested in hearing how you came about finding out to do this? What has the response been from your transplant team?
Ginger

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I just assumed what if the medications were low in my system and I took them separately? I also read medicines can together cause synergism. My doc says no problem.

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