Stopping Carvedilol (Coreg): When will the effects wear off?

Posted by teatime @teatime, Apr 28, 2016

Hi everyone,

I am glad to be a part of this community. Please foregive the long post. I was wondering if anyone has had a hard time while being on and going off Carvedilol (Coreg).

I am an active 45 year old mom of a young child. I have always tried to eat healthily and keep in shape (I do yoga, pilates and, run about 5k 2x per week). My BP has always been pretty good, but since my 40´s it has gone up a bit (heredity factors play a role). My BP and heart rate also "spike" when I get stressed or anxious, but for the most part are pretty level during normal times. I do have anxious moments, but I would not say anxiety has been a major life problem. At my last check (Feb 2016), and after wearing a 24 hour BP monitor, my cardiologist suggested I start Carvedilol 6.25 1x per day (quite a low dose) for the spikes and to keep the heart from getting too excited. I agreed that maybe it was a good idea and started over two months ago. Other than stimulating rapid bowel movements, I did not notice any side effects at first. I would say about three to four weeks into taking the Carvedilol, I began not sleeping well. I also noticed my heart pounding, like a bass drum, slowly and steadily, at times. Then the heart pounding began to wake me up at night (it turns out my HR was down in the high 40s at night). Some nights I even felt my chest muscles vibrate, as if a phone on silence mode was on top of my chest. I started to notice this more and more and then I would have a few normal nights, so I figured I would just talk about this at my next cardio check (booked out in June). I also noticed I was getting more and more anxious. I wasn't too sure why little things were beginning to bother me. I thought it was hormones, PMS, whatever, and started looking for someone like a therapist to talk to.

The previous week was bad. I woke up from a few nightmares and I started to panic in bed, just woken up from sleep. I had three nights of waking up to panic attacks and body shakes. The experiences made me very nervous. At this point I started looking into the side effects of Carvedilol and I was seeing not only chest pounding, but in rare cases reported effects of nightmares, visual disturbances, tremors, anxiety. I also know one does not simply stop a beta blocker, so we talked about tapering down. I tapered down for four days, and then I got in to see another cardiologist on Monday and he said just stop immediately. The effects are rare, but they have been noted. Going off this medication has been frightening. I feel weak and shaky all the time, and I get sporadic periods of pounding and muscle tremors in my legs, anxiety and fuzzy vision. I frequently get so cold I begin to shake. Yesterday I went back to the clinic for an EKG (normal) and some blood tests (including thyroid) and everything was normal. I am just assuming this is my body reacting and readapting itself after being on beta blockers. It has only been five days, but I am wondering if anyone out there has had similar experiences. How long did it take you to feel normal again? I ran a 5k just two weekends ago and yesterday I could hardly take a walk. Thanks for listening.

Interested in more discussions like this? Go to the Heart & Blood Health Support Group.

Hello, great! I ever heard of that. I will google it. I did take my first glass of water with 1 tblsp. of ACV mid morning. I still feel off balance and vision etc. I am sure it will take some time to adjust. I am also now going to google if it gets rid of plaque. I was told I also have asthereoclorosis , spelling?

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@oliver8112000

Hello my first post. My Cardiologist put me on lowest dose of Entresto to take 2 X a day Heart Failure/ MVP. I was then to add Carvedilol 3.125mg the following week 2 X day. Stooped Entresto the third day due to SE. Carvedilol no better!! Balance issues, vertigo, sleepiness, vision issues. Ended up in ER. Thought I was having T.I.A. or Heart Attack. Mind you my BP runs Low Normal. Not High. Have history of two cancers. First one Leukemia 1981 had Bone Marrow Transplant. Chemo and Total Body Radiation. Then BC 2007. Have many ‘late effects’ from all the TX’S. So I stopped taking Carvedilol on my own two days ago. I have only been taking it once a day at night. One 3.125mg little pill. I was also on Rosuvastatin 5mg since April 2023, 3 days week for DX of Cholesterol. Note, have bad Neuropathy, feet fingers hands. Always thinking from radiation , that was so long ago. And last Chemo TX for BC was 2/5/2008.
Neuropathy did not start until 4/11/2011. Three years later!
Statins can cause Neuropathy and make existing Neuropathy worse! So I have been racking my brain, why did it go down hill and has been getting so worse since summer, June of 2023? Bam! I started the Statin Drug Rosuvastatin that April and five months ago I decided to, like my Dr. Wanted me to do to get my Cholesterol even lower go from taking 5mg three days a week take it every day! I truly believe, based on what I researched last night, the Rosuvastatin has worsened my neuropathy. Thoughts?
Also, Apple Cider Vinegar mixed with water has lowered Cholesterol levels.
🤔
Thank you and I apologize for the long post. I am at my wits end.

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I have been injecting Repatha for 9 to 10 months now, and feel so much better. My LDL is down to 18!

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Hello my first post. My Cardiologist put me on lowest dose of Entresto to take 2 X a day Heart Failure/ MVP. I was then to add Carvedilol 3.125mg the following week 2 X day. Stooped Entresto the third day due to SE. Carvedilol no better!! Balance issues, vertigo, sleepiness, vision issues. Ended up in ER. Thought I was having T.I.A. or Heart Attack. Mind you my BP runs Low Normal. Not High. Have history of two cancers. First one Leukemia 1981 had Bone Marrow Transplant. Chemo and Total Body Radiation. Then BC 2007. Have many ‘late effects’ from all the TX’S. So I stopped taking Carvedilol on my own two days ago. I have only been taking it once a day at night. One 3.125mg little pill. I was also on Rosuvastatin 5mg since April 2023, 3 days week for DX of Cholesterol. Note, have bad Neuropathy, feet fingers hands. Always thinking from radiation , that was so long ago. And last Chemo TX for BC was 2/5/2008.
Neuropathy did not start until 4/11/2011. Three years later!
Statins can cause Neuropathy and make existing Neuropathy worse! So I have been racking my brain, why did it go down hill and has been getting so worse since summer, June of 2023? Bam! I started the Statin Drug Rosuvastatin that April and five months ago I decided to, like my Dr. Wanted me to do to get my Cholesterol even lower go from taking 5mg three days a week take it every day! I truly believe, based on what I researched last night, the Rosuvastatin has worsened my neuropathy. Thoughts?
Also, Apple Cider Vinegar mixed with water has lowered Cholesterol levels.
🤔
Thank you and I apologize for the long post. I am at my wits end.

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This is interesting. I take Coreg twice a day and have severe headaches almost daily. I never would have attributed the headaches to Coreg. This is food for thought.

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@krj1213

What do you mean by antihypertensive I really think that I have been over medicated I wish I never started taking blood pressure medicine I tried to stop coreg on my own but my heart was beating fast so I popped a pill of coreg and it settled down
it's crazy I was just searching about coreg and I ran across my own post and ur response crazy.....my BP is doing OK 158/91 little high but it's been steady for weeks but it seems I been ticking my own med my Doctor's are dumb as hell and seem like they know nothing I'm telling my cardiologist what to do know any doctors in jersey good with BP email me, anybody HELP!!!!

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Hello! I know this post is from 2017 but I’m curious to know if you were able to come off of Coreg? I was put on it for blood pressure as well and when I try to stop it my heart rate increases smh. The doctors are idiots and don’t believe that this is a side effect of the drug.

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@vbrooks82

@eileena.... You are exactly right you have to gradually take yourself off this drug... My doses have been decreased but its still hard for me to get. It out of my system... How long were you on it... Im kind of angry that i was giving this drug as an aide for my blood pressure but it actually keeps my blood pressure high and my never before anxiety even higher... Its a very scary drug and i pray its not damaging my heart when there wasnt an issue with my heart.. im soo scared and it really seems there is nothing i can do.. Ive been given anxiety meds but i dont want to rely on those i just want to feel better and get this medication out of my body

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I know this was all
The way back in 2017 but did Coreg make you have heart arrhythmias when trying to stop it?? I am also on it bc of my blood pressure and when trying to stop it I go in Afib smh

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@colleenyoung

Welcome @teatime,
Great first post! What a shock to go from running a 5k two weeks ago to hardly able to take a walk yesterday. I'm tagging @murryone @neeci @sittingscribe1 and @momma78 on this discussion, as they have mentioned that they are taking Carvedilol (Coreg) too. I'd also like to introduce you to @cynaburst @lynnkay1956 @PatMattos @Sensation @ronaldpetrovich @FrancineFafard @lepadelford

May I ask what heart condition you're taking the medication for?

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I really appreciate Mayo Connect, and have been participating in the Chronic Pain forum. Now I’d love some feedback about medications for hypertension and headaches. I’m taking Coreg and yes I’ve encountered head and gum “tightness “. When doctors have added anything else; calcium channel blockers and diuretics, the headaches become pounding. My PC just discerned that the added diuretic was most likely the problem, therefore I’m here asking for feedback from anyone who may have had a similar experience. Did you find any solution?
Thanks!
Sandy

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(reply to original post by teatime) Hi! Obviously, I have a similar problem, and just happened to be looking through the internet when I saw this post and joined the forum. You may have written further posts on this topic and I am interetsed in what happened with you. After I post I will check some of the other posts. Whatever the case, I see this post was written some time ago, and Im sure you're better now.
So I am a 72 year old man who has had high blood pressure for many years. I no longer smoke, I exercise and am at a reasonable weight. However it seems HBP runs in the family, regardless. I have taken Nifedipine for many years, too, and it did a great job until recently. Also, I have had on and off again problems with anxiety. My Dr prescribed Coreg, 6.25 twice a day, in addition to the Nifedipine.
It has been almost a month. No problem until a week or so ago. My BP was managed well, heart rate down. Then, I began to feel fatigue. At first I thought it was depression, but there was no sadness, no low self-esteem, just overwhelming fatigue!
I finally contacted to Dr after hours, tonight, and he said to simply quit taking it. The way he reacted made me think he has heard this from other patients before. I asked him if he would like to prescribe another BP med to take its place, and he said that we would discuss this next week when I was "back to normal". He also said that I was in no danger if my BP went up somewhat. We'll see.
I know this stuff works by calming the body down from the effects of adrenaline, and it did that job well, much TOO well, as a matter of fact, I felt my motivation and energy dissipate to almost nothing. Good thing I am retired, I doubt if I could work under this drug.
Not sure if I will have any withdrawal symptoms. I took the 6.25 twice a day, in fact. some days I took a half pill. I have now found I cannot tolerate this drug at all.

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Been on carvediol 40 mg. for about 4 years now. Given this drug because I have tried over 20 others over 30 year period. My bp was 230/95 at er 30 years ago. After 6 or more doctors no one got my bp below 140 with 2-3 meds daily. Went to a cardio surgen who put me on this med. My bp dropped to the 120's /70..........but my heart rate was down to 40. I was told that that was the rate of a marathon runner. A year ago I ended up in er with 20 heart rate and 900 blood sugar. After research I found this drug can trigger diabetes. Doctors can not see how I was walking and driving. This year I ended up in hospital with clogged kidneys from 7.4 diameter stones. They did not want to operate because my 40 h/r I told them that was normal for me. They thought I was crazy. Was taken off all meds in hospital. No blood pressure meds no Jardiance or insulin. I questioned this but they were the doctors. Was given 2 units of insulin after 4 days...........my normal dose is 40 units daily. Was taken off carvediol after discharge from hospital. My heart rate is about 56 now. Sleeping a lot better too. Was tired all the time before......told was my age. Not as tired all the time like before.

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I just want to note that almost everything that you mentioned in your feed I went through the same thing. I cannot believe they have this drug on the market without further testing it's capacity. I am a 55-year-old man. I also have hypertension which runs in the family lucky me right? Well just to reiterate I saw my cardiologist today and he took me off carvedilol today but I already read of last week on how to wing off of it you should never just try to stop all at once as there will be greater effects. I am now going on day five and I feel perfectly fine every now and then I get a little bit of heavy breathing where I'm trying to catch my breath The doctor says a couple more days and I will be fine. I had a lot of horrible nightmares and I noticed several days ago I had uncontrollable anxiety while out at dinner and I felt like I was so agitated by everyone talking around me that I just wanted to get up and scream. Now I am good I feel like this drug is finally making its way out of my system. The effects of the drug can linger up to 2 weeks the doctor said but not intensely so I am counting everyday until this drug wears itself out. On a good note it turns out that none of my heart arteries are blocked which was the reason why he put me on this medication 2 months ago. I really feel bad for the next person who has to take this and feels like they are actually doing something to progress their health when they realize this drug turns you into Jekyll or maybe hide they will definitely discontinue like we did hahaha Good luck and much success on your recovery from this drug also read all the reviews on Reddit you will be up almost all night reading all the horror stories that other people have experienced from this drug!

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