Does anybody have good results taking Azilect as a mono therapy?
Hi does anybody have good results taking Azilect as a mono therapy in early PD? Some say it also slows PD progression. I have moderate tremor of my left hand and arm. Thanks.
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Since 2020, has anyone else had experience with MAO-B inhibitors, like Azilect (rasagiline)? My husband has right-side tremors, mainly in his hand and we're looking for something for him to take that works with few (or no) side effects, based on others' experience. Thanks!
I started Azilect 10+ years ago as a mono therapy. Until a few years ago, my left-side tremor dominant PD was manageable with just Azilect and a low dose of Sinemet. Recently, I have had to add Amantadine to the Rytary and Sinemet I take. Observationally and comparatively, I feel it has had a positive impact on my PD progression.
I am now noticing some hesitancy in executive decision making. I have physical challenges which may or may not relate to PD, including foot fall and neuropathy. I also have anemia and MDS which are not linked to PD, as far as I can tell.
Keep in mind that Azilect is a difficult med to manage. It does not play well with some other meds. The food issue is not a major problem. PCP are not familiar with it and more than once I have had Rx’s prescribed by physicians (other than my Movement Disorder Specialist) pulled at my pharmacy because of contraindications. Azilect also seems to enhance the effects of other meds. I have tried twice to stop taking it in prep for surgery. The withdrawal symptoms were so severe I went back on it after the surgeries.
Would I take it again? I think I would look very carefully at the research as well as its compatibility with other meds you might be prescribed . When I started, there were some studies from Israel that seemed to indicate it could slow progression. Other info was pretty thin.