Has anyone microdosed with HOCM (in lieu of anti-depressants)?

I would ask the Cardiologist since I think this question requires professional help regarding side effects.

Hello @rmhc123. This is a very complex question. So much so, that even medical professionals warrant that more research needs to be done, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661823/.

In your case, @manuelpo gives simple, but prudent, advice. You'll likely need to talk with your provider. Because there is ongoing research, it may come down to what your cardiologist thinks is safe based on your situation. If you don't mind sharing, are you currently on anti-depressants? Do those have any contraindications with your HOCM?

i macrodosed with mushrooms taking metropol 25 mg. 2x 1.5 g and was fine have done it several times. deep spiritual healing

have HOCM with gradient 50-75

@joanallione, please inform your cardiologist that you also use mushrooms. Mushrooms and their active ingredient psilocybin are being researched for their potential to treat a range of psychiatric and behavioral disorders. But mushrooms are not regulated and are not yet approved by the FDA for any use.

You can also talk to your pharmacist about possible interactions to find out if psilocybin may reduce the effectiveness of your prescribed medications.

Joan, did your cardiologist recommend your current dosage of
metoprolol?