Has anyone had severe nasal congestion taking Repatha?

Posted by con123 @con123, May 15 7:19am

I just took my first injection of Repatha. About 4 days after, I woke with terrible nasal congestion, which has persisted for a week. My ENT suspected it was a reaction to the drug.

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Janell, Volunteer Mentor | @jlharsh | May 15 11:56am

Hello @con123 ,
Did your ENT provide explanation as to why this would be happening? I didn’t have your particular side effect but do hear others comment about it. It can be outright annoying, can’t it? I am learning side effects may be an indication of something bad or even good happening, your body responding to the drug. Was it your ENT that prescribed Repatha?

Sue, Volunteer Mentor | @sueinmn | May 15 10:03pm

@con123, That happened after my first 2 doses of Repatha, in fact I felt for 4 days like I had a cold. After a month, it didn't happen again - when I looked it up, it was one of the top 5 side effects.
In about the 3rd month, I had a backache for a couple days after 2 injections, but that is also gone.
Now, after almost a year on Repatha, my only symptom is feeling very tired the day of or day after my injection.
I'll live with it - statins we're a nightmare for me, and Repatha lowered my LDL by over 50% at 5 months. Waiting on the latest lipid panel results.

con123 | @con123 | May 16 4:52am

In reply to @jlharsh "Hello @con123 , Did your ENT provide explanation as to why this would be happening? I..." + (show)

My cardiologist prescribed it due to statin intolerance. I deferred starting it due to chronic sinusitis since nasal congestion, cold and flu like symptoms are a common side effect. I had surgery to fix the sinusitis, and when I was feeling better, started Repatha. 3 or 4 days after the injection, I woke up severely congested. The ENT said to discuss it with my cardiologist as a probable side effect.

Janell, Volunteer Mentor | @jlharsh | May 16 8:06pm

In reply to @con123 "My cardiologist prescribed it due to statin intolerance. I deferred starting it due to chronic sinusitis..." + (show)

Ahhh, good plan @con123
I see Sue has encouraging information about her experience. I am super curious to hear what you learn.
Janell (jlharsh)

con123 | @con123 | May 17 7:39am

In reply to @sueinmn "@con123, That happened after my first 2 doses of Repatha, in fact I felt for 4..." + (show)

Strangely my LDL decreased 50% over the 8 months I was taking NO cholesterol meds. and was in desired range but he wanted me to take Repatha to get the total number lower. Horrible pain with statins. I’ve had this congestion for a full week and next shot is due on Tuesday. I’m skipping it and discussing with my Dr. I was hoping I could tolerate it. The bruise at the injection site is just starting to fade.

missey | @missey | May 17 9:00am

In reply to @con123 "My cardiologist prescribed it due to statin intolerance. I deferred starting it due to chronic sinusitis..." + (show)

It is a side effect. I take a Sudafed and use a Nettie pot and it seems to help. I also went to urgent care and they gave me a prescription for TobraDex even though it’s off label use that really helped a whole lot!

vaniag | @vaniag | May 17 9:04am

I had 3 months of side effects on Repatha. Mild flu symptoms and aches in all the joints I have injured. After that, no problem. I have been on it for nearly 5 years… My only complaint is that I wished it worked better for me - but am getting about 50% decrease in LDL I am also on Nexletol - I have had no side effects from Nexletol at all.

Take good care of yourself and hugs,

Vania

tcarter1908 | @tcarter1908 | 2 days ago

In reply to @con123 "My cardiologist prescribed it due to statin intolerance. I deferred starting it due to chronic sinusitis..." + (show)

I’ve been extremely sick after my 6 dose of Repatha, The sinusitis is wicked with severe angioedema. Don’t do it!!

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