Has anyone had Folfirinox stop working and had to start a new chemo dr
I have stage IV pancreatic cancer. I had a cyst which turned out to be cancerous. Long story short, I had 20 sessions of Folfirinox when I noticed the CA19s were creeping upwards from Jan-April 2023. I had already made contact with MSK about CT guided high dose radiation and I was scheduled for 15 sessions in May which targeted the primary tumor and the area where they first saw a tiny spot in my liver. My subsequent CT scans could find no detectable area of concern in my liver so they targeted the area of the liver originally noted in in my very first scan.
I stopped chemo to let the radiation work and had 5 good months of feeling almost back to normal. I flew back to NYC this week for follow up, hoping I had several more chemo free months in front of me. Unfortunately, while primary pancreatic tumor is unchanged, the CT scan showed a new small spot on the liver. So doctors recommended I get back on chemo and suggested gemcitabine and/or other meds.
Can anyone tell me if they have had to switch chemo meds? What is the Gemcitabine Chemo like as far as side effects? Also, I was told that biopsies prior to chemo are needed to determine eligibility for clinical trials. Originally I was told that my biopsy had insufficient tissue to be conclusive. Since this is a new spot of concern should I have another biopsy prior to starting chemo again?
I do not live near a pancreatic cancer center so some of these trials may not be an option for me but I’m obviously willing to travel to an extent if need be. Thank you for any input.