Getting off of Seroquel

Posted by anniegk @anniegk, Jun 8, 2018

I have been on 300 mgs. Seroquel ER for over a year for augmenting my antidepressant which is 45 mgs. Of Mirtazapine. I decided to try and get off of the Seroquel. I was on 300mgs ER (extended release). I titrated down to 250 mg ER for 2 months without too many problems.than i titrated down to 200mgs ER just 5 days ago. My plan is to try to titrate off using ER tablets. My thinking is that perhaps the drug will remove its self from my system more gradually. I have had some nausea and a couple of episodes of diarrhea. I also have a very irregular heart beat and was started on 60 mgs of Propranolol ER (extended release) 4 weeks ago. It seems to be helping my heartbeat. I have wondered if the nausea and light headness is from the Propranolol, a Beta Blocker, or the dose reduction of the Seroquel. I also wonder if the way iam titrating the Seroquel is safe. My doctor says it will only take a couple of weeks…I think that is too fast of a taper after being on a drug for over a year. What do you think?

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@sears

And the powers that be say Benzos are bad? I think Effexor and Seroquel are much worse.

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Far worse. Coming off Klonopin was easier than Seroquel. It's so tricky and devious that most people (myself included) have no withdrawal until they're completely off of it. All I got from seroquel was 50 pounds of fat, damaged cholesterol, restless legs, infected head acne that required a trip to the hospital more than once. And it didn't even put me to sleep! It was unethically prescribed off-label and all it did was make me worse. Astra Seneca paid millions of dollars in fines for this exact reason:

"In April 2010, the U. S. Department of Justice fined Astra-Zeneca $520 million for the company's aggressive marketing of Seroquel for off-label uses. According to the Department of Justice, "the company recruited doctors to serve as authors of articles that were ghostwritten by medical literature companies and about studies the doctors in question did not conduct."

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Been doing ok. My nights are good (due to klonopin), appetite is great, any weight after the withdrawals came back. Anxiety is still a problem though. I'm 38 and this has always been an issue. Sometimes its mild and can be walked off, other times it leads to feeling ominous and sick. Klonopin has been helping, started from 0.75 then 0.5 and on to 0.25 but that last one was ineffective, had to move back up to 0.5/0.6 to restabilze. Also had to switch brands from accord to solco, accord is unpredictable and can cause headaches but it works fast. Solco takes its time (1-2 hours) but is more comfortable. Another problem that came up, for the last couple of days, at noon, I've been drowsy and wanted to nap. But doing so leads to anxiety, this is normal for me because my nights are affected. I was able to exercise at the park to relieve it, but it came back a few hours later and was treated with klonopin (a few hours before bed).

tl;dr When you quit seroquel: The symptoms you were using it to treat will more than likely come back, worse than before. In my case, its night/sleep time anxiety. That said, in my opinion, I feel using a low dose of a benzo is far safer than the side effects of seroquel.

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Was doing good for a while, exercise helped. Then got better, stopped exercise and within days the nausea and vomit came back. I went back home but want to go back to my parents. I've also increased my paxil from 10 to 20mg, I hope it helps. The klonopin does nothing anymore. Wish me luck.

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@chrisjc

Been doing ok. My nights are good (due to klonopin), appetite is great, any weight after the withdrawals came back. Anxiety is still a problem though. I'm 38 and this has always been an issue. Sometimes its mild and can be walked off, other times it leads to feeling ominous and sick. Klonopin has been helping, started from 0.75 then 0.5 and on to 0.25 but that last one was ineffective, had to move back up to 0.5/0.6 to restabilze. Also had to switch brands from accord to solco, accord is unpredictable and can cause headaches but it works fast. Solco takes its time (1-2 hours) but is more comfortable. Another problem that came up, for the last couple of days, at noon, I've been drowsy and wanted to nap. But doing so leads to anxiety, this is normal for me because my nights are affected. I was able to exercise at the park to relieve it, but it came back a few hours later and was treated with klonopin (a few hours before bed).

tl;dr When you quit seroquel: The symptoms you were using it to treat will more than likely come back, worse than before. In my case, its night/sleep time anxiety. That said, in my opinion, I feel using a low dose of a benzo is far safer than the side effects of seroquel.

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I agree! I think Seroquel and Effexor are far worse than any benzo.

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@sears

I agree! I think Seroquel and Effexor are far worse than any benzo.

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Days are ok, I'm exercising 2-3 hours. Appetite is alright. Nights and early mornings are dreadful. Early morning I'll have Intense panic attacks, and if I close my eyes to go back to sleep I immediately feel a sense of death and dread and have violent dry heaving. Its painful, to say the least. The past few nights were ok, fell asleep normally but last night I had insomnia. Couldn't close my eyes without the aforementioned panic attacks and vomiting. So I just stayed up watching TV. I eventually slept for maybe 2-3 hours, then woke up sick again. Took a low dose of klonopin, it warded off the vomiting but everything else remained. Shook it off, went for a walk at the park to clear my head. Exercise really helps the panic attacks and vomiting spells.

This is really messing up my life. I can't go back on it either, this has been more than a month since i went clean. Last time I fell back, I kept having to increase the dose to avoid withdrawal and with it came the old side effects that I've been away from for so long.

I'm also taking paxil, was on 10 for years but recently increase to 15, planning to increase to 20 after two weeks.

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Paxil has been at 15 for two weeks and 20 for almost a week. Things are getting better and the klonopin is working again.

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Please be careful with the paxil. Do some research, talk to your doctor.

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Yes, Sears, be careful with Paxil. It made me fall and my daughter is on it now and having bad effects.

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Can be worse than a benzo when trying to taper.

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lilypaws Hi pharris022. I was on Seroquel and had very bad side effects and had to get off of it right away. My daughter can tolerate it. I think you slowly going off of it is a good idea. Sounds like you have other problems too. I hope you get feeling better. Try smiling at yourself in the mirror everyday as fiesty76 suggested. Take care and they are bad drugs. I will talk to my daughter about getting off of Seroquel. She has trouble getting to sleep. She takes a lot of different meds to help her to get to sleep. I am on Lexapro and it's the best one I have ever taken. Of course I'm on Klonopin too. I have to take 2 mg of klonopin, a muscle relaxant, and Ambien to get to sleep. But it works and I wake up wide awake. But when I have my surgery the surgeon is putting me on Percocet, Tramadol, and Valium. Won't need those other meds then.

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@lilypaws

lilypaws Hi pharris022. I was on Seroquel and had very bad side effects and had to get off of it right away. My daughter can tolerate it. I think you slowly going off of it is a good idea. Sounds like you have other problems too. I hope you get feeling better. Try smiling at yourself in the mirror everyday as fiesty76 suggested. Take care and they are bad drugs. I will talk to my daughter about getting off of Seroquel. She has trouble getting to sleep. She takes a lot of different meds to help her to get to sleep. I am on Lexapro and it's the best one I have ever taken. Of course I'm on Klonopin too. I have to take 2 mg of klonopin, a muscle relaxant, and Ambien to get to sleep. But it works and I wake up wide awake. But when I have my surgery the surgeon is putting me on Percocet, Tramadol, and Valium. Won't need those other meds then.

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Why is he changing you to Valium? Klonopin has a very long half life also.

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@tiffanyvillier

Has anyone successfully “gotten off” seroquel?

I’ve been taking it for 5 years (100mgXR). I tried my own slow taper, cutting down by 25mg every 3 weeks. Once off, I ended up in psychiatric care for 2 weeks, and put right back on it. I also got a new diagnosis of “Schizophrenic” as a result of the stay.

I’m going to see my Psychiatrist in November and I’m going to ask about a supervised-taper of sorts.

The effects I don’t want to deal with anymore:
-Dead libido
-Yawning/Tremors from waking until around 6 hours later
-General feeling of malaise

Is it possible to be completely free of mood stabilizers? Or, are there any proven medications that don’t come with typical side-effects?

Some background:
My first manic episode was at 31 years of age. I was diagnosed as manic bipolar after being mostly awake for 6 days straight. (I would nod off and not realize I had gone to sleep.) I also quit drinking heavily, cold-turkey, 2 weeks prior.

Thanks for any input!

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Hi I was on a small 2.5mg lexapro a day antidepressant for depression and Lamotrigine 200mg for mood swings and bipolar.That was perfect for years even with some alcohol.I told them I was a bit flat at night and looked to alcohol for an upper so they put me on Seroquel and I don’t like it ,I wake at 1am ? Or 4 am then if I ever have a few beers with this stuff I choke at night and keep waking.Then I tried to chuck it away but then gets worse I can’t sleep at all for days ,anyway I’m taping off gradually with my doctor now and it’s going good.

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