getting mucus out of multifocal areas

Hi scoop. The 1200 mg extended releaserskiej - obce or twice a day

Hello ling. When I asked my pulmonologist and dr Griffith at NJH about it( I have the same issue) they said that mucus plugs pop up here and there, some disappear some new form, bubble like champagne, and except of airway clearance I do ( albuterol vest 7% sodium and Budesonide and my husband clapping on the most dense areas) I still have very little coughed up, some clear staff only, and the new ones form) there is not more I can do. I have a new cluster formed and dr Griffith said if time comes it will be removed surgically. Scary? Yes. May be it’s people who don’t cough up anything or very little. In the meantime I just do what I do and go day by day with my life probably like all of us. If others have heard something different on this issue please post a comment. Thank you

My husband does chest PT every evening. I am getting a vest in 2 weeks and do nebulizer treatments am and pm. Sometimes i bring up plugs but mostly clear mucous.
We do everything right but not good enough.
Had to start Ethambutol+ Azithromycin MWF

Directions say not to exceed 2 tablets in 24 hours. One tablet every 12 hours. I take 1-2 tablets every day but have only been using it for the last week!

I hope the diminishing returns others have posted about does not happen. The only other supplements I take are calcium with D3.

Arlo, Please keep us posted on your experiment. Splitting pills is generally ok but I have never tried on an extended release because of not being able to get a "true split."

If I read this article correctly there are two kinds of mucus in lungs, MUC5AC and MUC5B found in different parts/layers of the lungs. According to the article mucinex (aka GGE) significantly inhibited MUC5AC secretion, which I think means that mucinex reduces some mucus production. Maybe that's why we feel a bit better less congested on it?

It is a bit confusing. I thought the whole point of Mucinex was to help loosen the mucus you have so it can be expelled more easily? But if it reduces some mucus production that would support some saying it can have a drying effect? One thing I came across recently was that guaifenesin is a mild immune suppressant. I know sometimes when I take Mucinex I will feel better than usual that day. Other times no help at all. Maybe worse the next day?

Thank you so much for sharing your experiences. And i am sorry o hear that even you do everything right, you still could not get the plugs out. I wonder if the plugs are causing any infections because they are alway there in the lungs. And why it happens to some people. I hope we can find an answer and solution.
Take care and best luck!

Ling

if you search it comes up easily but here is one reference to that effect of guaifenesin (which is what Mucinex is)
https://mpkb.org/home/othertreatments/guaifenesin#:~:text=Even%20at%20normal%20over%20the%20counter%20doses%20guaifenesin%20is%20mildly%20immunosuppressive.