Generic Escitalopram Oxalate (Lexapro)

Dear Sir/Madam,
My name is Peter Klinski and I signed up to a support group called I need someone to
talk to. I'm sorry, but I just can't do it. It brings my depression on. Half of their problems
and medications I don't know a thing about. I thought I would be comforting them.
I'm sorry.

> Sincerely,
>
Peter J. Klinski

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> 03/20/2024 9:43 PM CDT Mayo Clinic Connect < nf+f29cb524+3011821@n1.hubapplication.com> wrote:
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> Mayo Clinic Connect
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> @mikeinohio https://connect.mayoclinic.org/member/00-45c09f47c8ecbc38388539/?utm_source=connect.mayoclinic.org&utm_medium=email&utm_campaign=greeter&utm_content=greeter_intro_userlink made their first post to depression & Anxiety Support Group.
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> Their discussion:
> Generic Escitalopram Oxalate (Lexapro)
> I have been on Lexapro and the generics for over 10 years. Not necessarily for anxiety or depression but more for anger management, or dark tunnel vision as my mother called it. Never physically violent but extremely angry and overstimulated. The medication has brightened my vision and allowed me to know that, if I am upset about something, it is legitimate. A true life changer!
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> I take 20 mg per day. At the point in which Lexapro became extremely expensive and no longer covered by insurance, I was lucky to be put on the generic made by Accord (a U.S. company). Over the last year or two, they have stopped production in the States. I have since found that every generic of this medication is definitely not the same, as I guess would make sense with chemistry of the brain. I have read other posts by people who have loved Accord and are nowlooking for an alternative. I was given the Solco version (China) and had extreme paranoia and even hallucinations. It’s a shame that most pharmacies currently seem to be pushing this one. I tried Torrent (India) and that had about zero effect, consistent with what I have read from others. I have taken two 10 mg Accord for several months, but that obviously does not have the same release rate of one 20 mg, and now that dose is just about gone as well.
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> I was hoping to find others with a similar issue and determine what manufactures of generic escitalopram oxalate are available in the U.S., as this is not very well publicized. And I’m open to recommendations for another Selective Serotonin Reuptake Inhibitor (SSRI) like Zoloft or Celexa and whether folks familiar with those generics have noticed significant variability and side effects between manufactures.
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@mikeinohio Welcome to Mayo Clinic Connect! It is true that sometimes the manufacturers of generics may use different "carrying agents" of the active ingredient. so they effects may not all be the same. I myself use Celexa, with no side issues. Some people experience weight gain with this medication, but I do not.

What does your prescribing doctor say about what you are seeing for side effects? Do they have any suggestions?
Ginger

The side effects are basically it doesn’t work at all or I get extreme paranoia/jitters/bit of hallucinations. Not anything like weight change or dry mouth or such. Or at least I wouldn’t mind those comparatively. Have you had various generic manufacturers of the Celexa with limited difference?

@mikeinohio I have been on Celexa three different times. in the last 20 years. In my own experience, there has been no marked difference in side effects, nor in efficacy. I am on a low dose of 10mg once a day.

I will be curious as other members chime in with their experience.
Ginger

It’s true that when I was on lexapro that it kept my anger at a normal level. I quit taking it because after over 12 years on it my anxiety and impatience started coming back and after quitting helped it to calm down. I still have little moments that I have to calm down and gather my anger up and cool off. I take propranolol 40g daily to help.

Thank you for sharing. I have read that the chemistry can change over the years.